Dual drug release of triamterene and aminophylline from poly (N-isopropylacrylamide) hydrogels

Nanomaterials and Nanotechnology

Volumn 2, Issue 1, 2012, Pages

  Castro, Emilio ^a   Mosquera, Víctor ^a   Katime, Issa ^b  

^a UNIVERSITY OF SANTIAGO DE COMPOSTELA   (Spain)

^b UNIVERSITY OF THE BASQUE COUNTRY UPV EHU   (Spain)

Author keywords

Diffusion; Drug delivery systems; Hydrogels; Polyamides; UV Vis spectroscopy

Indexed keywords

ACRYLIC MONOMERS; AMIDES; DIFFUSION; DRUG PRODUCTS; HYDROGELS; LIGHT SCATTERING; POLYAMIDES; PORE SIZE; TARGETED DRUG DELIVERY; ULTRAVIOLET VISIBLE SPECTROSCOPY;

ACTIVE INGREDIENTS; CONTROLLED RELEASE; DRUG DELIVERY SYSTEM; ENVIRONMENTAL ELECTRONICS; EXTERNAL STIMULUS; QUASI ELASTIC LIGHT SCATTERINGS; TEMPERATURE SENSITIVE; UV-VIS SPECTROSCOPY;

CONTROLLED DRUG DELIVERY;

EID: 84888589607     PISSN: None     EISSN: 18479804     Source Type: Journal    
DOI: 10.5772/50338     Document Type: Article

References (33)

1. L. Wei, C. Cai, J. Lin, T. Chen, Dual-drug delivery system based on hydrogel/micelle composites, Biomaterials, 30 (2009) 2606-2613.
2. D. Ma, K. Tu, L.-M. Zhang, Bioactive supramolecular hydrogel with controlled dual drug release characteristics, Biomacromolecules, 11 (2010) 2204- 2212.
3. M.D. Baumann, C.E. Kang, J.C. Stanwick, Y. Wang, H. Kim, Y. Lapitsky, M.S. Shoichet, An injectable drug delivery platform for sustained combination therapy, J. Control. Release, 138 (2009) 205-213.
4. U. Manna, S. Patil, Dual drug delivery microcapsules via layer-by-layer self-assembly, Langmuir, 25 (2009) 10515-10522.
5. L.Y. Qiu, Y.H. Bae, Self-assembled polyethyleniminegraft- poly(e-caprolactone) micelles as potential dual carriers of genes and anticancer drugs, Biomaterials, 28 (2007) 4132-4142.
6. X. Song, Y. Zhao, S. Hou, F. Xu, R. Zhao, J. He, Z. Cai, Y. Li, Q. Chen, Dual agents loaded PLGA nanoparticles: Systematic study of particle size and drug entrapment efficiency, Eur. J. Pharm. Biopharm., 69 (2008) 445-453.
7. W. Xia, J. Chang, J. Lin, J. Zhu, The pH-controlled dualdrug release from mesoporous bioactive glass/polypeptide graft copolymer nanomicelle composites, Eur. J. Pharm. Biopharm., 69 (2008) 546-552.
8. B.-J. Lee, S.-G. Ryu, J.-H. Cui, Controlled release of dual drug-loaded hydroxypropyl methylcellulose matrix tablet using drug-containing polymeric coatings, Int. J. Pharm., 188 (1999) 71-80.
9. J.S. Lee, J.W. Bae, Y.K. Joung, S.J. Lee, D.K. Han, K.D. Park, Controlled dual release of basic fibroblast growth factor and indomethacin from heparinconjugated polymeric micelle, Int. J. Pharm., 346 (2008) 57-63.
10. I. Katime, R. Novoa, E.D. de Apocada, E. Rodríguez, Release of theophylline and aminophylline from acrylic acid/n-alkyl methacrylate hydrogels, J. Polym. Sci. Part A, Polym. Chem., 42 (2004) 2756-2765.
11. Y.H. Lim, D. Kim, D.S. Lee, Drug releasing characteristics of thermo- and pH-sensitive interpenetrating polymer networks based on poly(Nisopropylacrylamide), J. Appl. Polym. Sci., 64 (1997) 2647-2655.
12. S.-X. Cheng, J.-T. Zhang, R.-X. Zhuo, Macroporous poly(N-isopropylacrylamide) hydrogels with fast response rates and improved protein release properties, J. Biomed. Res. Part A, 67 (2003) 96-103.
13. D.C. Coughlan, F.P. Quilty, O.I. Corrigan, Effect of drug physicochemical properties on swelling/deswelling kinetics and pulsatile drug release from thermoresponsive poly(N-isopropylacrylamide) hydrogels, J. Control. Release, 98 (2004) 97-114.
14. J.-Y. Wu, S.-Q. Liu, P. W.-S. Heng, Y.-Y. Yang, Evaluating proteins release from, and their interactions with, thermosensitive poly (Nisopropylacrylamide) hydrogels, J. Control. Release, 102 (2005) 361-372.
15. X.-Z. Zhang, Y.-Y. Yang, T.-S. Chung, K.-X. Ma, Preparation and characterization of fast response macroporous poly (N-isopropylacrylamide) hydrogels, Langmuir, 17 (2001) 6094-6099.
16. J.-T. Zhang, S.-X. Cheng, S.-W. Huang, R.-X. Zhuo, Temperature-sensitive poly(N-isopropylacrylamide) hydrogels with macroporous structure and fast response rate, Macromol. Rapid Commun., 24 (2003) 447-451.
17. W. Xue, I.W. Hamley, M.B. Huglin, Rapid swelling and deswelling of thermoreversible hydrophobically modified poly(N-isopropylacrylamide) hydrogels prepared by freezing polymerisation, Polymer, 43 (2002) 5181-5186.
18. J.-Y. Tsao, H.-H. Tsai, C.-P. Wu, P.-Y. Lin, S.-Y. Su, L.- D.Chen, F.-J, Tsai, Y. Tsai, Release of paeonol-@-CD complex from thermo-sensitive poly(Nisopropylacrylamide) hydrogels, Int. J. Pharm., 402 (2010) 123-128.
19. Y.-Y. Liu, X.-D. Fan, H. Hu, Z.-H. Tang, Release of chlorambucil from poly(N-isopropylacrylamide) hydrogels with @-cyclodextrin moieties, Macromol. Biosci., 4 (2004) 729-736.
20. C.S. Brazel, N.A. Peppas, Pulsatile local delivery of thrombolytic and antithrombotic agents using poly(N-isopropylacrylamide-co-methacrylic acid) hydrogels, J. Control. Release, 39 (1996) 57-64.
21. H. Zhang, C. Zhao, H. Cao, G. Wang, L. Song, G. Niu, H. Yang, J. Ma, S. Zhu, Hyperbranched poly(amineester) based hydrogels for controlled multi-drug release in combination chemotherapy, Biomaterials, 31 (2010) 5445- 5454.
22. N. Zhang, M. Liu, Y. Shen, J. Chen, L. Dai, C. Gao, Preparation, properties, and drug release of thermoand pH-sensitive poly((2-dimethylamino)ethyl methacrylate)/ poly(N,N-diethylacrylamide) semi- IPN hydrogels, J. Mater. Sci., 46 (2011) 1523-1534.
23. J. Chen, M. Liu, H. Liu, L. Ma, Synthesis, swelling and drug release behavior of poly(N,Ndiethylacrylamide- co-N-hydroxymethyl acrylamide) hydrogel, Mater. Sci. Eng. C, 29 (2009) 2116-2123.
24. I. Katime, N. Valderruten, J.R. Quintana, Controlled release of aminophylline from poly (Nisopropylacrylamide- co-itaconic acid) hydrogels, Polymer Int., 50 (2001) 869-874.
25. X. Huang, C.S. Brazel, On the importance and mechanisms of burst release in matrix-controlled drug delivery system, J. Control. Release, 73 (2001) 121-136.
26. P.L. Ritger, N.A. Peppas, A simple equation for description of solute release I. Fickian and non- Fickian release from non-swellable devices in the form of slabs, spheres, cylinders or discs, J. Control. Release, 5 (1987) 23-36.
27. R.W. Korsmeyer, R. Gunny, E. Doelker, P. Buri, N.A. Peppas, Mechanisms of solute release from porous hydrophilic polymers, Int. J. Pharm., 15 (1983) 25-35.
28. N.A. Peppas, G. Ponchol, D. Duchêne, Bioadhesive analysis of controlled-release systems. II. Time- Dependent bioadhesive stress in poly(acrylic acid)- containing systems, J. Control. Release., 5 (1987) 143- 149.
29. R.W. Korsmeyer, N.A. Peppas, Solute and penetrant diffusion in swellable polymers. III. Drug release from glassy poly(HEMA-co-NVP) copolymers, J. Control. Release, 1 (1984) 89-98.
30. C.S. Brazel, N.A. Peppas, Mechanisms of solute and drug transport in relaxing, swellable, hydrophilic glassy polymers, Polymer, 40 (1999) 3383-3398.
31. R. Pjanovic, N. Boskovic-Vragolovic, J. Veljkovic- Giga, R. Garic-Grulovic, S. Pejanovic, B. Bugarski, Diffusion of drugs from hydrogels and liposomes as drug carriers. J. Chem. Technol. Biotechnol., 85 (2010) 639-698.
32. M.D. Blanco, S. Guerrero, C. Teijon, R. Olmo, L. Pastrana, I. Katime, J.M. Teijon, Preparation and characterization of nanoparticulate poly(Nisopropylacrylamide) hydrogel for the controlled release of anti-tumour drugs. Polymer Int., 57 (2008) 1215-1225.
33. V. Sáez, E. Heráez, N.E. Valderruten, J.R. Quintana, I. Katime, Release kinetics of several drugs from polymeric hydrogels, Curr. Trends Polym. Sci., 7 (2002) 173-183.