DNA immunization with eukaryotic initiation factor-2α of Toxoplasma gondii induces protective immunity against acute and chronic toxoplasmosis in mice

Vaccine

Volumn 31, Issue 52, 2013, Pages 6225-6231

  Chen, Jia ^a   Huang, Si Yang ^a   Zhou, Dong Hui ^a   Li, Zhong Yuan ^a   Petersen, Eskild ^b   Song, Hui Qun ^a   Zhu, Xing Quan ^a,c  

^a INSTITUTE OF PLANT PROTECTION   (China)

^b AARHUS UNIVERSITY   (Denmark)

^c HEILONGJIANG BAYI AGRICULTURAL UNIVERSITY   (China)

Author keywords

DNA vaccine; Eukaryotic initiation factor 2 (TgIF2 ); Mice; Protective immunity; Toxoplasma gondii; Toxoplasmosis

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; DNA VACCINE; GAMMA INTERFERON; IMMUNOGLOBULIN G ANTIBODY; IMMUNOGLOBULIN G1; IMMUNOGLOBULIN G2A; INITIATION FACTOR 2ALPHA; INTERLEUKIN 2; PLASMID DNA; PROTECTIVE AGENT;

ANIMAL CELL; ARTICLE; BRAIN CYST; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CONTROLLED STUDY; DNA IMMUNIZATION; DNA VECTOR; DRUG CYTOTOXICITY; DRUG EFFICACY; DRUG POTENTIATION; FEMALE; HUMORAL IMMUNITY; IMMUNOFLUORESCENCE TEST; IMMUNOGENICITY; IMMUNOGLOBULIN PRODUCTION; IN VITRO STUDY; KUNMING MOUSE; MICROBIAL IMMUNITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SURVIVAL TIME; TH1 CELL; TOXOPLASMA GONDII; TOXOPLASMOSIS;

DNA VACCINE; EUKARYOTIC INITIATION FACTOR-2Α (TGIF2Α); MICE; PROTECTIVE IMMUNITY; TOXOPLASMA GONDII; TOXOPLASMOSIS;

ANIMALS; ANTIBODIES, PROTOZOAN; BRAIN; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; EUKARYOTIC INITIATION FACTOR-2; FEMALE; IMMUNOGLOBULIN G; INJECTIONS, INTRAMUSCULAR; INTERFERON-GAMMA; INTERLEUKIN-2; MICE; PROTOZOAN PROTEINS; PROTOZOAN VACCINES; SURVIVAL ANALYSIS; TH1 CELLS; TOXOPLASMA; TOXOPLASMOSIS, ANIMAL; VACCINES, DNA; VIRULENCE FACTORS;

EID: 84888438771     PISSN: 0264410X     EISSN: 18732518     Source Type: Journal    
DOI: 10.1016/j.vaccine.2013.10.034     Document Type: Article

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