Factors influencing adherence in long-term use of statins

Pharmacoepidemiology and Drug Safety

Volumn 22, Issue 12, 2013, Pages 1298-1307

  Warren, James R ^a,b   Falster, Michael O ^b   Fox, Danushka ^c,d   Jorm, Louisa ^b,c  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF WESTERN SYDNEY   (Australia)

^c SAX INSTITUTE   (Australia)

^d NSW Ministry of Health   (Australia)

Author keywords

Epidemiologic determinants; Medication adherence; Pharmacoepidemiology; Statins

Indexed keywords

HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR;

ADULT; AGED; ARTICLE; DISTRESS SYNDROME; EDUCATIONAL STATUS; EMPLOYMENT STATUS; FEMALE; HEALTH CARE ACCESS; HEALTH SERVICE; HUMAN; INCOME; LANGUAGE; MAJOR CLINICAL STUDY; MALE; MEDICATION COMPLIANCE; PRESCRIPTION; PRIORITY JOURNAL; PRIVATE HEALTH INSURANCE; REIMBURSEMENT; SENSITIVITY ANALYSIS; SMOKING;

EPIDEMIOLOGIC DETERMINANTS; MEDICATION ADHERENCE; PHARMACOEPIDEMIOLOGY; STATINS;

COMMUNICATION BARRIERS; DATABASES, FACTUAL; FEMALE; HEALTH SERVICES ACCESSIBILITY; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; INSURANCE, PHARMACEUTICAL SERVICES; LANGUAGE; MALE; MEDICATION ADHERENCE; MIDDLE AGED; NEW SOUTH WALES; PHARMACOEPIDEMIOLOGY; SMOKING; STRESS, PSYCHOLOGICAL;

EID: 84888437445     PISSN: 10538569     EISSN: 10991557     Source Type: Journal    
DOI: 10.1002/pds.3526     Document Type: Article

References (49)

1. Rodgers PT, Ruffin DM. Medication nonadherence--Part I: The health and humanistic consequences. Manag Care Interface 1998; 11(8): 58-60.
2. Heisler M, Hogan MM, Hofer TP, Schmittdiel JA, Pladevall M, Kerr EA. When more is not better: treatment intensification among hypertensive patients with poor medication adherence. Circulation 2008; 117(22): 2884-2892.
3. Pittman DG, Fenton C, Chen W, Haffner S, Pendergrass M. Relation of statin nonadherence and treatment intensification. Am J Cardiol 2012; 110(10): 1459-1463.
4. National Vascular Disease Prevention Alliance. Guidelines for the management of absolute cardiovascular disease risk: National Stroke Foundation; 2012.
5. Perk J, De Backer G, Gohlke H, et al. European Guidelines on cardiovascular disease prevention in clinical practice (version 2012). The Fifth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of nine societies and by invited experts). Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J 2012; 33(13): 1635-1701.
6. Benner JS, Glynn RJ, Mogun H, Neumann PJ, Weinstein MC, Avorn J. Long-term persistence in use of statin therapy in elderly patients. Jama 2002; 288(4): 455-461.
7. Thornley S, Marshall R, Chan WC, et al. Four out of ten patients are not taking statins regularly during the 12 months after an acute coronary event. Eur J Prev Cardiol 2012; 19(3): 349-357.
8. Rasmussen JN, Chong A, Alter DA. Relationship between adherence to evidence-based pharmacotherapy and long-term mortality after acute myocardial infarction. Jama 2007; 297(2): 177-186.
9. Ho PM, Magid DJ, Shetterly SM, et al. Medication nonadherence is associated with a broad range of adverse outcomes in patients with coronary artery disease. Am Heart J 2008; 155(4): 772-779.
10. Banks E, Redman S, Jorm L, et al. Cohort profile: the 45 and up study. Int J Epidemiol 2008; 37(5): 941-947.
11. Australian Government - Department of Health and Ageing. Pharmaceutical Benefits Scheme (PBS) - About the PBS. 2012; http://www.pbs.gov.au/pbs/about-the-pbs. [16 November 2012].
12. Australian Government - Department of Health and Ageing. New PBS Safety Net Thresholds. 2012; http://www.health.gov.au/internet/main/publishing.nsf/Content/pbs-safetynet-changes. [16 November 2012].
13. Australian Government - Department of Human Services. Concession and Health Care Cards. 2012; http://www.humanservices.gov.au/customer/subjects/concession-and-health-care-cards. [16 November 2012].
14. Andrade SE, Kahler KH, Frech F, Chan KA. Methods for evaluation of medication adherence and persistence using automated databases. Pharmacoepidemiol Drug Saf 2006; 15(8): 565-574; discussion 575-577.
15. WHO Collaborating Centre for Drug Statistics Methodology. ATC/DDD Index. 2011; http://www.whocc.no/atc_ddd_index/. [16 November 2012].
16. Spiegelman D, Hertzmark E. Easy SAS calculations for risk or prevalence ratios and differences. Am J Epidemiol 2005; 162(3): 199-200.
17. Zou G. A modified poisson regression approach to prospective studies with binary data. Am J Epidemiol 2004; 159(7): 702-706.
18. Andersen RM. Revisiting the behavioral model and access to medical care: does it matter? J Health Soc Behav 1995; 36(1): 1-10.
19. Fransen GA, Mesters I, Janssen MJ, Knottnerus JA, Muris JW. Which patient-related factors determine self-perceived patient adherence to prescribed dyspepsia medication? Health Educ Res 2009; 24(5): 788-798.
20. Jorm LR, Walter SR, Lujic S, Byles JE, Kendig HL. Home and community care services: a major opportunity for preventive health care. BMC Geriatr 2010; 10: 26.
21. Mabbott V, Robinson M, Segrave A, Brennan Q. Australian Statistics on Medicines 2010 edition: Australian Government - Department of Health and Ageing; 2012.
22. Kessler R, Mroczek D. Final Version of our Non-Specific Psychological Distress Scale [memo dated 3/10/94]. Survey Research Center of the Institute for Social Research: University of Michigan: Ann Arbor (MI), 1994.
23. Mehta S, Wells S, Riddell T, et al. Under-utilisation of preventive medication in patients with cardiovascular disease is greatest in younger age groups (PREDICT-CVD 15). J Prim Health Care 2011; 3(2): 93-101.
24. Gadkari AS, McHorney CA. Unintentional non-adherence to chronic prescription medications: how unintentional is it really? BMC Health Serv Res 2012; 12: 98.
25. Naderi SH, Bestwick JP, Wald DS. Adherence to drugs that prevent cardiovascular disease: meta-analysis on 376, 162 patients. Am J Med 2012; 125(9): 882-887 e881.
26. Lemstra M, Blackburn D, Crawley A, Fung R. Proportion and risk indicators of nonadherence to statin therapy: a meta-analysis. Can J Cardiol 2012; 28(5): 574-580.
27. George J, Shalansky SJ. Predictors of refill non-adherence in patients with heart failure. Br J Clin Pharmacol 2007; 63(4): 488-493.
28. Gehi AK, Ali S, Na B, Whooley MA. Self-reported medication adherence and cardiovascular events in patients with stable coronary heart disease: the heart and soul study. Arch Intern Med 2007; 167(16): 1798-1803.
29. Kulkarni SP, Alexander KP, Lytle B, Heiss G, Peterson ED. Long-term adherence with cardiovascular drug regimens. Am Heart J 2006; 151(1): 185-191.
30. Trivedi RB, Ayotte B, Edelman D, Bosworth HB. The association of emotional well-being and marital status with treatment adherence among patients with hypertension. J Behav Med 2008; 31(6): 489-497.
31. Lai EJ, Grubisic M, Palepu A, Quan H, King KM, Khan NA. Cardiac medication prescribing and adherence after acute myocardial infarction in Chinese and South Asian Canadian patients. BMC Cardiovasc Disord 2011; 11: 56.
32. Wisnivesky JP, Krauskopf K, Wolf MS, et al. The association between language proficiency and outcomes of elderly patients with asthma. Ann Allergy Asthma Immunol 2012; 109(3): 179-184.
33. Padilla R, Steiner JF, Havranek EP, Beaty B, Davidson AJ, Bull S. A comparison of different measures of acculturation with cardiovascular risk factors in Latinos with hypertension. J Immigr Minor Health 2011; 13(2): 284-292.
34. Cole JA, Norman H, Weatherby LB, Walker AM. Drug copayment and adherence in chronic heart failure: effect on cost and outcomes. Pharmacotherapy 2006; 26(8): 1157-1164.
35. Karaca-Mandic P, Swenson T, Abraham JM, Kane RL. Association of Medicare Part D medication out-of-pocket costs with utilization of statin medications. Health Serv Res 2012; 48(4): 1311-1333.
36. Doran E, Robertson J, Salkeld G. Pharmaceutical Benefits Scheme cost sharing, patient cost consciousness and prescription affordability. Aust Health Rev 2011; 35(1): 37-44.
37. Kemp A, Glover J, Preen DB, Bulsara M, Semmens J, Roughead EE. From the city to the bush: increases in patient co-payments for medicines have impacted on medicine use across Australia. Aust Health Rev 2013; 37(1): 4-10.
38. Karakurt P, Kasikci M. Factors affecting medication adherence in patients with hypertension. J Vasc Nurs 2012; 30(4): 118-126.
39. Underhill C, Bartel R, Goldstein D, et al. Mapping oncology services in regional and rural Australia. Aust J Rural Health 2009; 17(6): 321-329.
40. Mealing NM, Banks E, Jorm LR, Steel DG, Clements MS, Rogers KD. Investigation of relative risk estimates from studies of the same population with contrasting response rates and designs. BMC Med Res Methodol 2010; 10: 26.
41. Steiner JF, Prochazka AV. The assessment of refill compliance using pharmacy records: methods, validity, and applications. J Clin Epidemiol 1997; 50(1): 105-116.
42. Vermeire E, Hearnshaw H, Van Royen P, Denekens J. Patient adherence to treatment: three decades of research. A comprehensive review. J Clin Pharm Ther 2001; 26(5): 331-342.
43. Mabotuwana T, Warren J, Harrison J, Kenealy T. What can primary care prescribing data tell us about individual adherence to long-term medication?-comparison to pharmacy dispensing data. Pharmacoepidemiol Drug Saf 2009; 18(10): 956-964.
44. Ponsonby AL, Dwyer T, Couper D. Is this finding relevant? Generalisation and epidemiology. Aust N Z J Public Health 1996; 20(1): 54-56.
45. Tran DT, Jorm L, Lujic S, Bambrick H, Johnson M. Country of birth recording in Australian hospital morbidity data: accuracy and predictors. Aust N Z J Public Health 2012; 36(4): 310-316.
46. Ng SP, Korda R, Clements M, et al. Validity of self-reported height and weight and derived body mass index in middle-aged and elderly individuals in Australia. Aust N Z J Public Health 2011; 35(6): 557-563.
47. Bressington D, Mui J, Gray R. Factors associated with antipsychotic medication adherence in community-based patients with schizophrenia in Hong Kong: A cross sectional study. Int J Ment Health Nurs 2013; 22(1): 35-46.
48. Stewart A, Kamberg CJ. Physical functioning measures. In Measuring Functioning and Well-Being: the Medical Outcomes Study Approach, Stewart A, Ware J (eds), Durham (NC): Duke University Press; 1992.
49. Australian Institute of Health and Welfare. Rural Regional and Remote Health: A guide to remoteness classifications. Canberra: Australian Institute of Health and Welfare; 2004.