Factors associated with antipsychotic medication adherence in community-based patients with schizophrenia in Hong Kong: A cross sectional study

International Journal of Mental Health Nursing

Volumn 22, Issue 1, 2013, Pages 35-46

  Bressington, Dan ^a   Mui, Jolene ^c   Gray, Richard ^b  

^a CANTERBURY CHRIST CHURCH UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF EAST ANGLIA   (United Kingdom)

^c CASTLE PEAK HOSPITAL   (Hong Kong)

Author keywords

Adherence; Antipsychotic; Insight; Schizophrenia; Treatment attitude

Indexed keywords

NEUROLEPTIC AGENT;

ADOLESCENT; ADULT; AGED; ARTICLE; AWARENESS; BRIEF PSYCHIATRIC RATING SCALE; CHECKLIST; COMMUNITY MENTAL HEALTH CENTER; CROSS-SECTIONAL STUDY; FEMALE; HUMAN; MALE; MEDICATION COMPLIANCE; MIDDLE AGED; NURSING; PATIENT EDUCATION; PSYCHIATRIC NURSING; PSYCHOLOGICAL ASPECT; PSYCHOLOGY; SCHIZOPHRENIA; VERY ELDERLY; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; ANTIPSYCHOTIC AGENTS; AWARENESS; BRIEF PSYCHIATRIC RATING SCALE; CHECKLIST; COMMUNITY MENTAL HEALTH CENTERS; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MALE; MEDICATION ADHERENCE; MIDDLE AGED; PATIENT MEDICATION KNOWLEDGE; PSYCHIATRIC NURSING; SCHIZOPHRENIA; SCHIZOPHRENIC PSYCHOLOGY; YOUNG ADULT;

EID: 84872664875     PISSN: 14458330     EISSN: 14470349     Source Type: Journal    
DOI: 10.1111/j.1447-0349.2012.00830.x     Document Type: Article

References (51)

1. Adams, S. G., Jr. & Howe, J. T. (1993). Predicting medication compliance in a psychotic population. Journal of Nervous and Mental Disorders, 181, 558-560.
2. Adewuya, A. O., Ola, B. A., Mosaku, S. K., Fatoye, F. O. & Eegunranti, A. B. (2006). Attitude towards antipsychotics among out-patients with schizophrenia in Nigeria. Acta Psychiatrica Scandinavica, 2006, 1-5.
3. Ascher-Svanum, H., Zhu, B., Faries, D., Landbloom, R., Swartz, M. & Swanson, J. (2006). Time to discontinuation of atypical versus typical antipsychotics in the naturalistic treatment of schizophrenia. BMC Psychiatry (Serial online) 6, 8 [Cited 1 Nov 2011]. Available from: URL: http://www.biomedcentral.com/content/pdf/1471-244X-6-8.pdf
4. Baby, R. S., Gupta, S. & Sagar, R. (2009). Attitudes and subjective reasons of medication compliance among outpatients with schizophrenia in India. Internet Journal of Epidemiology (Serial online) 7, 1 [Cited 1 Dec 2011]. Available from: URL: http://www.ispub.com/journal/the-internet-journal-of-epidemiology/volume-7-number-1/attitudes-and-subjective-reasons-of-medication-compliance-and-noncompliance-among-outpatients-with-schizophrenia-in-india.html
5. Barbui, C., Kikkert, M., Mazzi, M. A. etal (2009). Comparison of patient and clinician perspectives in the assessment of antipsychotic medication adherence. Psychopathology, 42 (5), 311-317.
6. Birchwood, M., Smith, J., Drury, V., Healy, J., Macmillan, F. & Slade, M. (1994). A self-report insight scale for psychosis: Reliability, validity and sensitivity to change. Acta Psychiatrica Scandinavica, 89 (1), 62-67.
7. Byrne, M. K. & Deane, F. (2011). Enhancing patient adherence: Outcomes of medication alliance training on therapeutic alliance, insight, adherence, and psychopathology with mental health patients. International Journal of Mental Health Nursing, 20, 284-295.
8. Chung, K. F. & Wong, M. C. (2004). Experience of stigma in Chinese mental health patients in Hong Kong. The Psychiatrist, 28, 451-454.
9. Day, J. C., Wood, G., Dewey, M. & Bentall, R. P. (1995). Liverpool university neuroleptic side effect rating scale. British Journal of Psychiatry, 166, 650-653.
10. Day, J. C., Bentall, R. P., Robert, C. etal. (2005). Attitudes toward antipsychotic medication: The impact of clinical variables and relationships with health professionals. Archives of General Psychiatry, 62 (7), 717-724.
11. Dolder, C. R., Lacro, J. P., Dunn, L. B. & Jeste, D. V. (2002). Antipsychotic medication adherence: Is there a difference between typical and atypical agents? American Journal of Psychiatry, 159, 103-108.
12. Fialko, L., Garety, P. A., Kuipers, E. etal. (2008). A large-scale validation study of the Medication Adherence Rating Scale (MARS). Schizophrenia Research, 100 (1-3), 53-59.
13. Fleischhacker, W. W., Meise, U., Gunther, V. & Kurz, M. (1994). Compliance with antipsychotic drug treatment: Influence of side effects. Acta Psychiatrica Scandinavica. Supplementum, 382, 11-15.
14. Gianfrancesco, F. D., Rajagopalan, K., Sajatovic, M. & Wang, R. (2006). Treatment adherence among patients with schizophrenia treated with atypical and typical antipsychotics. Psychiatry Research, 144, 177-189.
15. Gray, R., Bressington, D., Lathlean, J. & Mills, A. (2008). Relationship between adherence, symptoms, treatment attitudes, satisfaction and side effects in prisoners taking antipsychotic medication. Journal of Forensic Psychology and Psychiatry, 19 (3), 335-351.
16. Hofer, A., Kemmler, G., Eder, U., Honeder, M., Hummer, M. & Fleischhacker, W. W. (2002). Attitudes toward antipsychotics among outpatient clinic attendees with schizophrenia. Journal of Clinical Psychiatry, 63, 49-53.
17. Hogan, T. P., Awad, A. G. & Eastwood, R. (1983). A self-report scale predictive of drug compliance in schizophrenics: Reliability and discriminative validity. Psychological Medicine, 13, 177-183.
18. Hui, C. L. M., Chen, E. Y. C., Kan, C. S., Yip, K. C., Law, C. W. & Chiu, C. P. Y. (2006). Anti-psychotics adherence among out-patients with schizophrenia in Hong Kong. Keio Journal of Medicine, 55 (1), 9-14.
19. Johnstone, E. C., Macmillan, J. F., Frith, C. D., Benn, D. K. & Crow, T. J. (1990). Further investigation of the predictors of outcome following first schizophrenic episodes. British Journal of Psychiatry, 157, 182-189.
20. Kane, J. M. (2003). Strategies for improving compliance in treatment of schizophrenia by using a long-acting formulation of an antipsychotic: Clinical studies. Journal of Clinical Psychiatry, 64 (Suppl. 16), 34-40.
21. Kikkert, M. J., Schene, A. H., Koeter, M. W. J. etal. (2006). Medication adherence in schizophrenia: Exploring patients', carers' and professionals' views. Schizophrenia Bulletin, 32, 786-794.
22. Kikkert, M. J., Koeter, M. W. J., Dekker, J. J. M. etal. (2011). The predictive validity of subjective adherence measures in patients with schizophrenia. International Journal of Methods in Psychiatric Research, 20 (2), 73-81.
23. Lacro, J. P., Dunn, L. B., Dolder, C. R. etal. (2002). Prevalence of and risk factors for medication nonadherence in patients with schizophrenia: A comprehensive review of recent literature. Journal of Clinical Psychiatry, 63, 892-909.
24. Lang, K., Meyers, J. L., Korn, J. R. etal. (2010). Medication adherence and hospitalization among patients with schizophrenia treated with antipsychotics. Psychiatric Services, 61, 1239-1247.
25. Lanouette, N. M., Folsom, D. P., Sciolla, A. & Jeste, D. V. (2009). Psychotropic medication nonadherence among United States Latinos: A comprehensive literature review. Psychiatric Services, 60, 157-174.
26. Lee, S., Chiu, M. Y. L., Tsang, A., Chui, H. & Kleinman, A. (2006). Stigmatizing experience and structural discrimination associated with the treatment of schizophrenia in Hong Kong. Social Science and Medicine, 62 (7), 1685-1696.
27. Lingjaerde, O., Ahlfors, U. G., Bech, P., Dencker, S. J. & Elgen, K. (1987). The UKU side effect rating scale. A new comprehensive rating scale for psychotropic drugs and a crosssectional study of side effects in neuroleptic-treated patients. Acta Psychiatrica Scandinavica. Supplementum, 334, 1-100.
28. Marder, S. R. (2003). Overview of partial compliance. Journal of Clinical Psychiatry, 64 (Suppl. 16), 3-9.
29. Masand, P. S. & Narasimhan, M. (2006). Improving adherence to antipsychotic pharmacotherapy. Current Clinical Pharmacology, 1, 47-56.
30. McEvoy, J. P., Howe, A. C. & Hogarty, G. E. (1984). Differences in the nature of relapse and subsequent inpatient course between medication-compliant and noncompliant schizophrenic patients. Journal Nervous and Mental Disorders, 172, 412-416.
31. Mills, A., Lathlean, J., Bressington, D., Forrester, A., van Veenhuyzen, W. & Gray, R. (2010). Prisoners' experiences of antipsychotic medication: Influences on adherence. Journal of Forensic Psychology and Psychiatry, 2010, 1-16.
32. NICE (2008). National Institute for Health and Clinical Excellence implementation uptake report: Atypical antipsychotic drugs for the treatment of schizophrenia. NICE Technology Appraisal, 43, 1-5.
33. Novick, D., Haro, J. M., Suarez, D., Perez, V., Dittmann, R. W. & Haddad, P. M. (2010). Predictors and clinical consequences of non-adherence with antipsychotic medication in the outpatient treatment of schizophrenia. Psychiatry Research, 176, 109-113.
34. Olfson, M., Mechanic, D., Hansell, S., Boyer, C. A., Walkup, J. & Weiden, P. (2000). Predicting medication noncompliance after hospital discharge among patients with schizophrenia. Psychiatric Services, 51 (2), 216-222.
35. Opolka, J. L., Rascati, K. L., Brown, C. M. & Gibson, P. J. (2003). The role of ethnicity in predicting medication adherence. The Annals of Pharmacotherapy, 37 (5), 625-630.
36. Overall, J. E. & Gorham, D. R. (1962). The brief psychiatric rating scale. Psychological Reports, 10, 799-812.
37. Perkins, D. (1990). Adherence to antipsychotic medications. Journal of Clinical Psychiatry, 60 (Suppl. 21), 25-30.
38. Perkins, D. (2002). Predictors of non-compliance in patients with schizophrenia. Journal of Clinical Psychiatry, 63, 1121-1128.
39. Puschner, B., Born, A., Giebler, A., Helm, H., Leese, M. & Bindman, J. (2006). Adherence to medication and quality of life in people with schizophrenia: Results of a European multicentre study. Journal of Nervous and Mental Disease, 194, 746-752.
40. Robinson, D. R., Woerner, M. G., Ma, J. etal. (1999). Predictors of relapse following response from a first episode of schizophrenia or schizoaffective disorder. Archives General Psychiatry, 56, 241-247.
41. Rosenheck, R., Chang, S., Choe, Y. etal. (2000). Medication continuation and compliance: A comparison of patients treated with clozapine and haloperidol. Journal of Clinical Psychiatry, 61 (5), 382-386.
42. Rossi, A., Pacifico, R. & Stratta, P. (2009). Attitudes toward medication and the clinical variables in schizophrenia: Structural equation models. Patient Preference and Adherence, 3, 305-309.
43. Schwartz, R. C., Cohen, B. N. & Grubaugh, A. (1997). Does insight affect long-term inpatient treatment outcome in chronic schizophrenia? Comprehensive Psychiatry, 38, 283-288.
44. Shi, L., Ascher-Svanum, H., Zhu, B., Faries, D., Montgomery, W. & Marder, S. R. (2007). Taking first-generation depot antipsychotics or oral antipsychotics for schizophrenia. Psychiatric Services, 58, 482-488.
45. Thompson, K., Kulkarni, J. & Sergejew, A. A. (2000). Reliability and validity of a new Medication Adherence Rating Scale (MARS) for the psychoses. Schizophrenia Research, 42, 241-247.
46. Trauer, T. & Sacks, T. (2000). The relationship between insight and medication adherence in severely mentally ill clients treated in the community. Acta Psychiatrica Scandinavica, 102, 211-216.
47. Valenstein, M., Blow, F. C., Copeland, L. A. etal. (2004). Poor antipsychotic adherence among patients with schizophrenia: Medication and patient factors. Schizophrenia Bulletin, 30 (2), 255-264.
48. Valenstein, M., Ganoczy, D., McCarthy, J. F., Myra Kim, H., Lee, T. A. & Blow, F. C. (2006). Antipsychotic adherence over time among patients receiving treatment for schizophrenia: A retrospective review. Journal of Clinical Psychiatry, 67, 1542-1550.
49. Ventura, J., Green, M., Schaner, A. & Liberman, R. (1993). Training and quality assurance with the Brief Psychiatric Rating Scale: The 'drift busters'. International Journal of Methods in Psychiatric Research, 3, 221-244.
50. Voruganti, L., Oyewumi, L., Cernovsky, Z., Zirul, S. & Awad, A. (2000). Comparative evaluation of conventional and novel antipsychotic drugs with reference to their subjective tolerability, side-effect profile and impact on quality of life. Schizophrenia Research, 43, 135-145.
51. Weiden, P. J., Kozma, C., Grogg, A. & Locklear, J. (2004). Partial compliance and risk of rehospitalisation among California Medicaid patients with schizophrenia. Psychiatric Services, 55, 886-891.