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Volumn 21, Issue 24, 2013, Pages 7604-7611
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Synthesis, docking and pharmacological evaluation of novel homo- and hetero-bis 3-piperazinylpropylindole derivatives at SERT and 5-HT1A receptor
a
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Author keywords
5 Hydroxytryptamine 1A receptor; Bivalent ligands; Docking; Piperazinylpropylindole derivatives; Serotonin transporter
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Indexed keywords
1,4 BIS[3 (1H 3 INDOLYL)PROPYL]PIPERAZINE;
1,4 BIS[3 (5 BROMO 1H 3 INDOLYL)PROPYL]PIPERAZINE;
1,4 BIS[3 (5 FLUORO 1H 3 INDOLYL]PROPYL)PIPERAZINE;
1,4 BIS[3 (5 METHOXY 1H 3 INDOLYL]PROPYL)PIPERAZINE;
3 [3 [4 [3 (1H 3 INDOLYL)PROPYL] 1 PIPERAZINYL]PROPYL] 5 BROMO 1H INDOL;
3 [3 [4 [3 (1H 3 INDOLYL)PROPYL] 1 PIPERAZINYL]PROPYL] 5 FLUORO 1H INDOL;
3 [3 [4 [3 (1H 3 INDOLYL)PROPYL] 1 PIPERAZINYL]PROPYL] 5 METHOXY 1H INDOL;
3 [3 [4 [3 (1H INDOL 3 YL)PROPYL]PIPERAZIN 1 YL]PROPYL] 1H INDOLE DERIVATIVE;
5 BROMO 3 [3 [4 [3 (5 FLUORO 1H 3 INDOLYL)PROPYL]PIPERAZINYL]PROPYL] 1H INDOL;
5 BROMO 3 [3 [4 [3 (5 METHOXY 1H 3 INDOLYL)PROPYL]PIPERAZINYL]PROPYL] 1H INDOL;
5 FLUORO 3 [3 [4 [3 (5 METHOXY 1H 3 INDOLYL)PROPYL]PIPERAZINYL]PROPYL] 1H INDOL;
CITALOPRAM;
INDOLE DERIVATIVE;
SEROTONIN 1A RECEPTOR;
SEROTONIN TRANSPORTER;
UNCLASSIFIED DRUG;
ANIMAL TISSUE;
ARTICLE;
BINDING AFFINITY;
CONTROLLED STUDY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HUMAN;
HUMAN CELL;
IN VITRO STUDY;
MOLECULAR DOCKING;
NONHUMAN;
RAT;
5-HYDROXYTRYPTAMINE 1A RECEPTOR;
BIVALENT LIGANDS;
DOCKING;
PIPERAZINYLPROPYLINDOLE DERIVATIVES;
SEROTONIN TRANSPORTER;
DOSE-RESPONSE RELATIONSHIP, DRUG;
HUMANS;
INDOLES;
MODELS, MOLECULAR;
MOLECULAR DOCKING SIMULATION;
MOLECULAR STRUCTURE;
PIPERAZINES;
RECEPTOR, SEROTONIN, 5-HT1A;
SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;
STRUCTURE-ACTIVITY RELATIONSHIP;
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EID: 84888432240
PISSN: 09680896
EISSN: 14643391
Source Type: Journal
DOI: 10.1016/j.bmc.2013.10.036 Document Type: Article |
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Times cited : (12)
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References (24)
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