The Edinger-Westphal nucleus II: Hypothalamic afferents in the rat

Journal of Chemical Neuroanatomy

Volumn 54, Issue , 2013, Pages 5-19

  da Silva, André V ^a,b   Torres, Kelly R ^a,b   Haemmerle, Carlos A ^a   Céspedes, Isabel C ^a,c   Bittencourt, Jackson C ^a  

^a UNIVERSITY OF SÃO PAULO   (Brazil)

^b SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^c FEDERAL UNIVERSITY OF SÃO PAULO   (Brazil)

Author keywords

Afferents; Corticotropin releasing factor; Long Evans rats; Neuronal tracers; Stress response; Urocortin 1

Indexed keywords

AMINE; ANTISERUM; DEXTRAN; FLUOROGOLD; UROCORTIN I;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTIBODY SPECIFICITY; ARCUATE NUCLEUS; ARTICLE; BIOTINYLATION; CELL LABELING; CONTROLLED STUDY; EDINGER WESTPHAL NUCLEUS; HYPOTHALAMIC PARAVENTRICULAR NUCLEUS; HYPOTHALAMUS; HYPOTHALAMUS NUCLEUS; IMMUNOREACTIVITY; INTERPOSITUS NUCLEUS; LATERAL HYPOTHALAMUS; MALE; MEDIAL VESTIBULAR NUCLEUS; NERVE FIBER TRANSPORT; NONHUMAN; POSTERIOR HYPOTHALAMUS; PRIORITY JOURNAL; RAT; RETROGRADE NERVE FIBER TRANSPORT; SENSORY NERVE; SUBFORNICAL ORGAN; SYNAPTIC POTENTIAL; ZONA INCERTA;

AFFERENTS; ARC; ARCUATE NUCLEUS; BDA; BIOTINYLATED DEXTRAN AMINE; CART; CHAT; CHOLINE ACETYLTRANSFERASE; COCAINE- AND AMPHETAMINE-REGULATED TRANSCRIPT; CORTICOTROPIN-RELEASING FACTOR; CRF; CY; CYANINE; DAB; DIAMINOBENZIDINE TETRAHYDROCHLORIDE; DK; EDINGER-WESTPHAL; EDINGER-WESTPHAL CENTRAL PROJECTIONS; EW; EWCP; FAST BLUE; FB; FG; FLUORO-GOLD; IMMUNOREACTIVITY; IR; KPBS; LATERAL HYPOTHALAMIC AREA; LATERAL HYPOTHALAMIC AREA, ANTERIOR PART; LATERAL HYPOTHALAMIC AREA, POSTERIOR (MAMMILLARY) PART; LATERAL HYPOTHALAMIC AREA, TUBERAL PART; LATERAL PREOPTIC AREA; LC; LHA; LHA(A); LHA(P); LHA(T); LOCUS COERULEUS; LONG-EVANS RATS; LPO; NEURONAL TRACERS; NUCLEUS OF DARKSCHEWITSCH; ORGANUM VASCULOSUM OF THE LAMINA TERMINALIS; OVLT; PARAVENTRICULAR NUCLEUS OF THE HYPOTHALAMUS; PH; POSTERIOR HYPOTHALAMIC NUCLEUS; POTASSIUM PHOSPHATE-BUFFERED SALINE; PVH; SFO; SO; STRESS RESPONSE; SUBFORNICAL ORGAN; SUPRAOPTIC NUCLEUS; UCN1; UROCORTIN 1;

AFFERENT PATHWAYS; ANIMALS; BRAIN STEM; HYPOTHALAMUS; IMMUNOHISTOCHEMISTRY; MALE; RATS; RATS, LONG-EVANS;

EID: 84888429479     PISSN: 08910618     EISSN: 18736300     Source Type: Journal    
DOI: 10.1016/j.jchemneu.2013.04.001     Document Type: Article

References (51)

1. Abrahamson E.E., Moore R.Y. The posterior hypothalamic area: chemoarchitecture and afferent connections. Brain Research 2001, 889:1-22.
2. Bachtell R.K., Weitemier A.Z., Galvan-Rosas A., Tsivkovskaia N.O., Risinger F.O., Phillips T.J., Grahame N.J., Ryabinin A.E. The Edinger-Westphal-lateral septum urocortin pathway and its relationship to alcohol consumption. Journal of Neuroscience 2003, 23:2477-2487.
3. Bienkowski M.S., Rinaman L. Common and distinct neural inputs to the medial central nucleus of the amygdala and anterior ventrolateral bed nucleus of stria terminalis in rats. Brain Structure & Function 2013, 218:187-208.
4. Bittencourt J.C., Vaughan J., Arias C., Rissman R.A., Vale W.W., Sawchenko P.E. Urocortin expression in rat brain: evidence against a pervasive relationship of urocortin-containing projections with targets bearing type 2 CRF receptors. Journal of Comparative Neurology 1999, 415:285-312.
5. Bland B.H., Konopacki J., Kirk I.J., Oddie S.D., Dickson C.T. Discharge patterns of hippocampal theta-related cells in the caudal diencephalon of the urethan-anesthetized rat. Journal of Neurophysiology 1995, 74:322-333.
6. Brailoiu G.C., Dun S.L., Brailoiu E., Inan S., Yang J., Chang J.K., Dun N.J. Nesfatin-1: distribution and interaction with a G protein-coupled receptor in the rat brain. Endocrinology 2007, 148:5088-5094.
7. Breen L.A., Burde R.M., Loewy A.D. Brainstem connections to the Edinger-Westphal nucleus of the cat: a retrograde tracer study. Brain Research 1983, 261:303-306.
8. Buccafusco J.J., Brezenoff H.E. Pharmacological study of a cholinergic mechanism within the rat posterior hypothalamic nucleus which mediates a hypertensive response. Brain Research 1979, 165:295-310.
9. Camacho A., Phillips M.I. Horseradish peroxidase study in rat of the neural connections of the organum vasculosum of the lamina terminalis. Neuroscience Letters 1981, 25:201-204.
10. Cespedes I.C., de Oliveira A.R., da Silva J.M., da Silva A.V., Sita L.V., Bittencourt J.C. mRNA expression of corticotropin-releasing factor and urocortin 1 after restraint and foot shock together with alprazolam administration. Peptides 2010, 31:2200-2208.
11. Douglass J., Daoud S. Characterization of the human cDNA and genomic DNA encoding CART: a cocaine- and amphetamine-regulated transcript. Gene 1996, 169:241-245.
12. Foo K.S., Brismar H., Broberger C. Distribution and neuropeptide coexistence of nucleobindin-2 mRNA/nesfatin-like immunoreactivity in the rat CNS. Neuroscience 2008, 156:563-579.
13. Gamlin P.D., Reiner A. The Edinger-Westphal nucleus: sources of input influencing accommodation, pupilloconstriction, and choroidal blood flow. Journal of Comparative Neurology 1991, 306:425-438.
14. Gaszner B., Csernus V., Kozicz T. Urocortinergic neurons respond in a differentiated manner to various acute stressors in the Edinger-Westphal nucleus in the rat. Journal of Comparative Neurology 2004, 480:170-179.
15. Geerling J.C., Shin J.W., Chimenti P.C., Loewy A.D. Paraventricular hypothalamic nucleus: axonal projections to the brainstem. Journal of Comparative Neurology 2010, 518:1460-1499.
16. Hillebrand J.J., de Wied D., Adan R.A. Neuropeptides, food intake and body weight regulation: a hypothalamic focus. Peptides 2002, 23:2283-2306.
17. Kakiya S., Yokoi H., Arima H., Iwasaki Y., Oki Y., Oiso Y. Central administration of urocortin inhibits vasopressin release in conscious rats. Neuroscience Letters 1998, 248:144-146.
18. Korosi A., Schotanus S., Olivier B., Roubos E.W., Kozicz T. Chronic ether stress-induced response of urocortin 1 neurons in the Edinger-Westphal nucleus in the mouse. Brain Research 2005, 1046:172-179.
19. Koylu E.O., Couceyro P.R., Lambert P.D., Kuhar M.J. Cocaine- and amphetamine-regulated transcript peptide immunohistochemical localization in the rat brain. Journal of Comparative Neurology 1998, 391:115-132.
20. Kozicz T., Bittencourt J.C., May P.J., Reiner A., Gamlin P.D., Palkovits M., Horn A.K., Toledo C.A., Ryabinin A.E. The Edinger-Westphal nucleus: a historical, structural, and functional perspective on a dichotomous terminology. Journal of Comparative Neurology 2011, 519:1413-1434.
21. Kozicz T., Bordewin L.A., Czeh B., Fuchs E., Roubos E.W. Chronic psychosocial stress affects corticotropin-releasing factor in the paraventricular nucleus and central extended amygdala as well as urocortin 1 in the non-preganglionic Edinger-Westphal nucleus of the tree shrew. Psychoneuroendocrinology 2008, 33:741-754.
22. Kozicz T., Korosi A., Korsman C., Tilburg-Ouwens D., Groenink L., Veening J., van Der Gugten J., Roubos E., Olivier B. Urocortin expression in the Edinger-Westphal nucleus is down-regulated in transgenic mice over-expressing neuronal corticotropin-releasing factor. Neuroscience 2004, 123:589-594.
23. Kozicz T., Li M., Arimura A. The activation of urocortin immunoreactive neurons in the Einger-Westphal nucleus following stress in rats. Stress 2001, 4:85-90.
24. Kozicz T., Yanaihara H., Arimura A. Distribution of urocortin-like immunoreactivity in the central nervous system of the rat. Journal of Comparative Neurology 1998, 391:1-10.
25. Martin J.R., Knuepfer M.M., Beinfeld M.C., Westfall T.C. Mechanism of pressor response to posterior hypothalamic injection of neuropeptide Y. American Journal of Physiology 1989, 257:H791-H798.
26. Miselis R.R. The subfornical organ's neural connections and their role in water balance. Peptides 1982, 3:501-502.
27. Miselis R.R., Shapiro R.E., Hand P.J. Subfornical organ efferents to neural systems for control of body water. Science 1979, 205:1022-1025.
28. National Research Council Guidelines for the Care and Use of Mammals in Neuroscience and Behavioral Research 2003, The National Academies Press, Washington.
29. Okere B., Xu L., Roubos E.W., Sonetti D., Kozicz T. Restraint stress alters the secretory activity of neurons co-expressing urocortin-1, cocaine- and amphetamine-regulated transcript peptide and nesfatin-1 in the mouse Edinger-Westphal nucleus. Brain Research 2010, 1317:92-99.
30. Paxinos G., Watson C. The Rat Brain in Stereotaxic Coordinates 2007, Elsevier, Amsterdam.
31. Roste G.K., Dietrichs E. Cerebellar cortical and nuclear afferents from the Edinger-Westphal nucleus in the cat. Anatomy and Embryology 1988, 178:59-65.
32. Rouwette T., Klemann K., Gaszner B., Scheffer G.J., Roubos E.W., Scheenen W.J., Vissers K., Kozicz T. Differential responses of corticotropin-releasing factor and urocortin 1 to acute pain stress in the rat brain. Neuroscience 2011, 183:15-24.
33. Sakai K., Yoshimoto Y., Luppi P.H., Fort P., el Mansari M., Salvert D., Jouvet M. Lower brainstem afferents to the cat posterior hypothalamus: a double-labeling study. Brain Research Bulletin 1990, 24:437-455.
34. Santos-Júnior, E.D.dos, 2005. Neurochemical characterization and study of the oculomotor accessory nucleus projections, Anatomy. University of Sao Paulo, Sao Paulo, p. 89.
35. Saper C.B., Swanson L.W., Cowan W.M. An autoradiographic study of the efferent connections of the lateral hypothalamic area in the rat. Journal of Comparative Neurology 1979, 183:689-706.
36. Schmued L.C., Fallon J.H. Fluoro-Gold: a new fluorescent retrograde axonal tracer with numerous unique properties. Brain Research 1986, 377:147-154.
37. Schmued L.C., Heimer L. Iontophoretic injection of fluoro-gold and other fluorescent tracers. Journal of Histochemistry and Cytochemistry 1990, 38:721-723.
38. Simerly R.B. Anatomical substrates of hypothalamic integration. The Rat Nervous System 2004, 335-368. Elsevier, San Diego. 3rd ed. G. Paxinos (Ed.).
39. Spina M., Merlo-Pich E., Chan R.K., Basso A.M., Rivier J., Vale W., Koob G.F. Appetite-suppressing effects of urocortin, a CRF-related neuropeptide. Science 1996, 273:1561-1564.
40. Strassman A., Mason P., Eckenstein F., Baughman R.W., Maciewicz R. Choline acetyltransferase immunocytochemistry of Edinger-Westphal and ciliary ganglion afferent neurons in the cat. Brain Research 1987, 423:293-304.
41. Swanson L.W. The hypothalamus. Handbook of Chemical Neuroanatomy 1987, 1-124. Elsevier, Amsterdam. A. Bjorklund, T. Hokfelt, L.W. Swanson (Eds.).
42. Szabadi E. Modulation of physiological reflexes by pain: role of the locus coeruleus. Frontiers in Integrative Neuroscience 2012, 6:94.
43. Vasconcelos L.A., Donaldson C., Sita L.V., Casatti C.A., Lotfi C.F., Wang L., Cadinouche M.Z., Frigo L., Elias C.F., Lovejoy D.A., Bittencourt J.C. Urocortin in the central nervous system of a primate (Cebus apella): sequencing, immunohistochemical, and hybridization histochemical characterization. Journal of Comparative Neurology 2003, 463:157-175.
44. Vaughan J., Donaldson C., Bittencourt J., Perrin M.H., Lewis K., Sutton S., Chan R., Turnbull A.V., Lovejoy D., Rivier C., et al. Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor. Nature 1995, 378:287-292.
45. Viau V., Sawchenko P.E. Hypophysiotropic neurons of the paraventricular nucleus respond in spatially, temporally, and phenotypically differentiated manners to acute vs. repeated restraint stress: rapid publication. Journal of Comparative Neurology 2002, 445:293-307.
46. Warwick R. The ocular parasympathetic nerve supply and its mesencephalic sources. Journal of Anatomy 1954, 88:71-93.
47. Weisinger R.S., Blair-West J.R., Burns P., Denton D.A., McKinley M.J., Purcell B., Vale W., Rivier J., Sunagawa K. The inhibitory effect of hormones associated with stress on Na appetite of sheep. Proceedings of the National Academy of Sciences of the United States of America 2000, 97:2922-2927.
48. Weninger S.C., Peters L.L., Majzoub J.A. Urocortin expression in the Edinger-Westphal nucleus is up-regulated by stress and corticotropin-releasing hormone deficiency. Endocrinology 2000, 141:256-263.
49. Wessendorf M.W. Fluoro-Gold: composition, and mechanism of uptake. Brain Research 1991, 553:135-148.
50. Xu L., Bloem B., Gaszner B., Roubos E.W., Kozicz T. Sex-specific effects of fasting on urocortin 1, cocaine- and amphetamine-regulated transcript peptide and nesfatin-1 expression in the rat Edinger-Westphal nucleus. Neuroscience 2009, 162:1141-1149.
51. Yamamoto H., Maeda T., Fujimura M., Fujimiya M. Urocortin-like immunoreactivity in the substantia nigra, ventral tegmental area and Edinger-Westphal nucleus of rat. Neuroscience Letters 1998, 243:21-24.