Immature platelet fraction can help adjust therapy in refractory thrombotic microangiopathic hemolytic anemia cases

Transfusion and Apheresis Science

Volumn 49, Issue 3, 2013, Pages 644-646

  Kier, Yelena E ^a,b   Stempak, Lisa M ^a,b   Maitta, Robert W ^a,b  

^a UNIVERSITY HOSPITALS OF CLEVELAND   (United States)

^b CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

IPF; Therapeutic plasma exchange; Thrombotic microangiopathy

Indexed keywords

LACTATE DEHYDROGENASE; PREDNISONE; VON WILLEBRAND FACTOR CLEAVING PROTEINASE;

ADULT; ARTICLE; BLOODY DIARRHEA; BONE MARROW BIOPSY; CASE REPORT; DRUG MEGADOSE; ESCHERICHIA COLI INFECTION; FEMALE; HEMATOPOIESIS; HEMOLYTIC ANEMIA; HUMAN; KIDNEY FAILURE; LACTATE DEHYDROGENASE BLOOD LEVEL; PLASMAPHERESIS; PLATELET FRACTION; STEROID THERAPY; THROMBOCYTE COUNT; THROMBOCYTE FUNCTION; THROMBOCYTOPENIA; THROMBOCYTOPOIESIS; THROMBOTIC THROMBOCYTOPENIC PURPURA;

%-IPF; THERAPEUTIC PLASMA EXCHANGE; THROMBOTIC MICROANGIOPATHY;

ADAM PROTEINS; ANEMIA, HEMOLYTIC; BLOOD PLATELETS; FEMALE; HUMANS; MIDDLE AGED; PLASMA EXCHANGE; THROMBOTIC MICROANGIOPATHIES;

EID: 84888427674     PISSN: 14730502     EISSN: 18781683     Source Type: Journal    
DOI: 10.1016/j.transci.2013.07.005     Document Type: Article

References (12)

1. George J.N. How I treat patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Blood 2000, 96:1223-1229.
2. Tandon N.N., Rock G., Jamieson G.A. Anti-CD36 antibodies in thrombotic thrombocytopenic purpura. Br J Haematol 1994, 88:816-825.
3. Medina P.J., Sipols J.M., George J.N. Drug-associated thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Curr Opin Hematol 2001, 8:286-293.
4. Briggs C., Kunka S., Hart D., Oguni S., Machin S.J. Assessment of an immature platelet fraction (IPF) in peripheral thrombocytopenia. Br J Haematol 2004, 126:93-99.
5. Yamaoka G., Kubota Y., Nomura T., Inage T., Arai T., Kitanaka A., et al. The immature platelet fraction is a useful marker for predicting the timing of platelet recovery in patients with cancer after chemotherapy and hematopoietic stem cell transplantation. Int J Lab Hematol 2010, 32:e208-e216.
6. Park Y.A., Waldrum M.R., Marques M.B. Platelet count and prothrombin time help distinguish thrombotic thrombocytopenic purpura-hemolytic uremic syndrome from disseminated intravascular coagulation in adults. Am J Clin Pathol 2010, 133:460-465.
7. Levandovsky M., Harvey D., Lara P., Wun T. Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS): a 24-year clinical experience with 178 patients. J Hematol Oncol 2008, 1:23.
8. Kim J.W., Kim I., Oh K.H., Yoon S.S., Oh M.D., Song Y.W., et al. Therapeutic plasma exchange in patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: the 10-year experience of a single center. Hematology 2011, 16:73-79.
9. Vesely S.K., George J.N., Lammle B., Studt J.D., Alberio L., El-Harake M.A., et al. ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients. Blood 2003, 102:60-68.
10. Abe Y., Wada H., Tomatsu H., Sakaguchi A., Nishioka J., Yabu Y., et al. A simple technique to determine thrombopoiesis level using immature platelet fraction (IPF). Thromb Res 2006, 118:463-469.
11. Barsam S.J., Psaila B., Forestier M., Page L.K., Sloane P.A., Geyer J.T., et al. Platelet production and platelet destruction: assessing mechanisms of treatment effect in immune thrombocytopenia. Blood 2011, 117:5723-5732.
12. Sugimori N., Kondo Y., Shibayama M., Omote M., Takami A., Sugimori C., et al. Aberrant increase in the immature platelet fraction in patients with myelodysplastic syndrome: a marker of karyotypic abnormalities associated with poor prognosis. Eur J Haematol 2009, 82:54-60.