Thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS): A 24-year clinical experience with 178 patients

Journal of Hematology and Oncology

Volumn 1, Issue 1, 2008, Pages

  Levandovsky, Mark ^a   Harvey, Danielle ^b   Lara, Primo ^c,d   Wun, Ted ^c,d  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d VA NORTHERN CALIFORNIA HEALTH CARE SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; COHORT ANALYSIS; FEMALE; HEMOLYTIC UREMIC SYNDROME; HUMAN; MALE; MIDDLE AGED; PLASMA; PLASMAPHERESIS; PROGNOSIS; RETROSPECTIVE STUDY; THROMBOCYTE COUNT; THROMBOTIC THROMBOCYTOPENIC PURPURA; TREATMENT OUTCOME;

ADULT; AGED; COHORT STUDIES; FEMALE; HEMOLYTIC-UREMIC SYNDROME; HUMANS; MALE; MIDDLE AGED; PLASMA; PLASMA EXCHANGE; PLATELET COUNT; PROGNOSIS; PURPURA, THROMBOTIC THROMBOCYTOPENIC; RETROSPECTIVE STUDIES; TREATMENT OUTCOME;

EID: 70450123543     PISSN: None     EISSN: 17568722     Source Type: Journal    
DOI: 10.1186/1756-8722-1-23     Document Type: Article

References (29)

1. George JN: How I treat patients with thrombotic thrombocy-topenic purpura-hemolytic uremic syndrome. Blood 2000, 96:1223-9. (Pubitemid 30658447)
2. George JN: Clinical practice. Thrombotic thrombocytopenic purpura. N Engl J Med 2006, 354:1927-35. (Pubitemid 43872694)
3. Ruggenenti P, Remuzzi G: Thrombotic microangiopathies. Crit RevOncol Hematol 1991, 11:243-65.
4. Gillis S: The thrombocytopenic purpuras. Recognition and management. Drugs 1996, 51:942-53. (Pubitemid 26164164)
5. Thompson CE, Damon LE, Ries CA, Linker CA: Thrombotic microangiopathies in the 1980s: clinical features, response to treatment, and the impact of the human immunodeficiency virus epidemic. Blood 1992, 80:1890-5.
6. Gasser C, Gautier E, Steck A, Siebenmann RE, Oechslin R: [Hemolytic-uremic syndrome: bilateral necrosis of the renal cortex in acute acquired hemolytic anemia.]. Schweiz Med Wochenschr 1955, 85:905-9.
7. Moake JL, Byrnes JJ, Troll JH, Rudy CK, Weinstein MJ, Colannino NM, Hong SL: Abnormal VIII: von Willebrand factor patterns in the plasma of patients with the hemolytic-uremic syndrome. Blood 1984, 64:592-8. (Pubitemid 14073475)
8. Furlan M, Robles R, Galbusera M, Remuzzi G, Kyrle PA, Brenner B, Krause M, Scharrer I, Aumann V, Mittler U, Solenthaler M, Lammle B: von Willebrand factor-cleaving protease in thrombotic thrombocytopenic purpura and the hemolytic-uremic syndrome. N Engl J Med 1998, 339:1578-84. (Pubitemid 28536132)
9. Furlan M, Robles R, Solenthaler M, Lammle B: Acquired deficiency of von Willebrand factor-cleaving protease in a patient with thrombotic thrombocytopenic purpura. Blood 1998, 91:2839-46. (Pubitemid 28227534)
10. Tsai HM, Lian EC: Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura. N Engl J Med 1998, 339:1585-94. (Pubitemid 28536133)
11. Fujikawa K, Suzuki H, McMullen B, Chung D: Purification of human von Willebrand factor-cleaving protease and its identification as a new member of the metalloproteinase family. Blood 2001, 98:1662-6.
12. Levy GG, Nichols WC, Lian EC, Foroud T, McClintick JN, McGee BM, Yang AY, Siemieniak DR, Stark KR, Gruppo R, Sarode R, Shurin SB, Chandrasekaran V, Stabler SP, Sabio H, Bouhassira EE, Upshaw JD Jr, Ginsburg D, Tsai HM: Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. Nature 2001, 413:488-94. (Pubitemid 32938741)
13. Hosler GA, Cusumano AM, Hutchins GM: Thrombotic thrombo-cytopenic purpura and hemolytic uremic syndrome are distinct pathologic entities. A review of 56 autopsy cases. Arch Pathol Lab Med 2003, 127:834-9. (Pubitemid 36792310)
14. Laurence J: Pathological and therapeutic distinctions in HUS/ TTP. Lancet 2000, 355:497-8. (Pubitemid 30085170)
15. Amorosi EL, Karpatkin S: Antiplatelet treatment of thrombotic thrombocytopenic purpura. Ann Intern Med 1977, 86:102-6. (Pubitemid 8020231)
16. Bell WR, Braine HG, Ness PM, Kickler TS: Improved survival in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Clinical experience in 108 patients. N Engl J Med 1991, 325:398-403.
17. Kwaan HC, Soff GA: Management of thrombotic thrombocyto-penic purpura and hemolytic uremic syndrome. Semin Hematol 1997, 34:159-66. (Pubitemid 27175074)
18. Lara PN Jr, Coe TL, Zhou H, Fernando L, Holland PV, Wun T: Improved survival with plasma exchange in patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome. Am J Med 1999, 107:573-9.
19. Rock GA, Shumak KH, Buskard NA, Blanchette VS, Kelton JG, Nair RC, Spasoff RA: Comparison of plasma exchange with plasma infusion in the treatment of thrombotic thrombocytopenic purpura. Canadian Apheresis Study Group. N Engl J Med 1991, 325:393-7.
20. Vesely SK, George JN, Rath W: Long Term Clinical Outcoms of Thrombotic Thrombocytopenic Purpura-Hemolytic Uremic Syndrome (TTP-HUS) Among Different Patient Groups. Blood 1999, 94:15a.
21. Vesely SK, George JN, Lammle B, Studt JD, Alberio L, El-Harake MA, Raskob GE: ADAMTS13 activity in thrombotic thrombocytopenic purpura-hemolytic uremic syndrome: relation to presenting features and clinical outcomes in a prospective cohort of 142 patients. Blood 2003, 102:60-8. 101182/blood-2003-01-0193. 2003-01-0193 [pii] (Pubitemid 36759636)
22. Rose M, Eldor A: High incidence of relapses in thrombotic thrombocytopenic purpura. Clinical study of 38 patients. Am J Med 1987, 83:437-44.
23. Bukowski R: Plasma exchange in the thrombotic microangiopathies. J Clin Apheresis 1985, 2:282-6. (Pubitemid 15237188)
24. Shamseddine A, Saliba T, Aoun E, Chahal A, El-Saghir N, Salem Z, Bazarbachi A, Khalil M, Taher A: Thrombotic thrombocytopenic purpura: 24 years of experience at the American University of Beirut Medical Center. J Clin Apher 2004, 19:119-24. 101002/ jca.20004 (Pubitemid 39403316)
25. Clark WF, Rock GA, Buskard N, Shumak KH, LeBlond P, Anderson D, Sutton DM: Therapeutic plasma exchange: an update from the Canadian Apheresis Group. Ann Intern Med 1999, 131:453-62. 199909210-00011 [pii] (Pubitemid 29444437)
26. Zheng XL, Kaufman RM, Goodnough LT, Sadler JE: Effect of plasma exchange on plasma ADAMTS13 metalloprotease activity, inhibitor level, and clinical outcome in patients with idiopathic and nonidiopathic thrombotic thrombocytopenic purpura. Blood 2004, 103:4043-9. 101182/blood-2003-11-4035. 2003-11-4035 [pii] (Pubitemid 38685342)
27. Moore JC, Hayward CP, Warkentin TE, Kelton JG: Decreased von Willebrand factor protease activity associated with thrombocytopenic disorders. Blood 2001, 98:1842-6.
28. Veyradier A, Obert B, Houllier A, Meyer D, Girma JP: Specific von Willebrand factor-cleaving protease in thrombotic microangiopathies: a study of 111 cases. Blood 2001, 98:1765-72.
29. Peyvandi F, Lavoretano S, Palla R, Feys HB, Vanhoorelbeke K, Battaglioli T, Valsecchi C, Canciani MT, Fabris F, Zver S, Reti M, Mikovic D, Karimi M, Giuffrida G, Laurenti L, Mannucci PM: ADAMTS13 and anti-ADAMTS13 antibodies as markers for recurrence of acquired thrombotic thrombocytopenic purpura during remission. Haematologica 2008, 93:232-9. haematol.11739 [pii]. 103324/haematol.11739 (Pubitemid 351397711)