Development and validation of a dried blood spot assay for the quantification of ribavirin using liquid chromatography coupled to mass spectrometry

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 944, Issue , 2014, Pages 18-24

  Jimmerson, Leah C ^a   Zheng, Jia Hua ^a   Bushman, Lane R ^a   MacBrayne, Christine E ^a   Anderson, Peter L ^a   Kiser, Jennifer J ^a  

^a UNIVERSITY OF COLORADO   (United States)

Author keywords

Analytical method; Dried blood spot; Hepatitis C; LC MS MS; Nucleoside analog; Ribavirin

Indexed keywords

ANALYTICAL METHOD; DRIED BLOOD SPOTS; HEPATITIS C; LC-MS/MS; NUCLEOSIDE ANALOGS; RIBAVIRIN;

AMIDES; ASSAYS; CHROMATOGRAPHY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY;

BLOOD;

METHANOL; RIBAVIRIN;

ARTICLE; BLOOD SAMPLING; CLINICAL ARTICLE; CONTROLLED STUDY; DRIED BLOOD SPOT TESTING; DRUG BLOOD LEVEL; FREEZE THAWING; HEMATOCRIT; HEMOLYTIC ANEMIA; HUMAN; NORMAL HUMAN; PRIORITY JOURNAL; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ROOM TEMPERATURE; TANDEM MASS SPECTROMETRY; VALIDATION STUDY;

ABOVE LIMIT OF QUANTITATION; ALQ; ANALYTICAL METHOD; DBS; DRIED BLOOD SPOT; DRIED BLOOD SPOTS; HCT; HEMATOCRIT; HEPATITIS C; LC-MS/MS; LIQUID CHROMATOGRAPHY TANDEM-MASS SPECTROMETRY; LLOQ; LOWER LIMIT OF QUANTITATION; NUCLEOSIDE ANALOG; PHARMACOKINETICS/DYNAMICS; PK-PD; QC; QUALITY CONTROL; RBV; RIBAVIRIN; ROOM TEMPERATURE; RT; STANDARD; STD; ULTRA-PURE WATER; UPH2O;

CHROMATOGRAPHY, LIQUID; DRIED BLOOD SPOT TESTING; DRUG STABILITY; HUMANS; LINEAR MODELS; REPRODUCIBILITY OF RESULTS; RIBAVIRIN; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 84888424003     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2013.10.035     Document Type: Article

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