Potential biomarkers of nonobstructive azoospermia identified in microarray gene expression analysis

Fertility and Sterility

Volumn 100, Issue 6, 2013, Pages

  Malcher, Agnieszka ^a   Rozwadowska, Natalia ^a   Stokowy, Tomasz ^b,c   Kolanowski, Tomasz ^a   Jedrzejczak, Piotr ^d   Zietkowiak, Wojmir ^e   Kurpisz, Maciej ^a  

^a INSTITUTE OF HUMAN GENETICS   (Poland)

^b INSTITUTE OF ONCOLOGY   (Poland)

^c SILESIAN UNIVERSITY OF TECHNOLOGY   (Poland)

^d POZNAN UNIVERSITY OF MEDICAL SCIENCES   (Poland)

^e Regional Hospital   (Poland)

Author keywords

Azoospermia; biomarkers; infertility; microarrays

Indexed keywords

BIOLOGICAL MARKER; CALPAIN; CALPAIN 11; UNCLASSIFIED DRUG; TUMOR MARKER; TUMOR PROTEIN;

ADULT; ARTICLE; AZOOSPERMIA; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOPLASM; DOWN REGULATION; GENE EXPRESSION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LEYDIG CELL; MALE; MICROARRAY ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SERTOLI CELL ONLY SYNDROME; SPERMATOCYTE; SPERMATOGENESIS; SPERMATOZOON; TESTICULAR SPERM EXTRACTION; UPREGULATION; WESTERN BLOTTING; WILLIAMS BEUREN SYNDROME; Y CHROMOSOME; FEASIBILITY STUDY; GENE EXPRESSION PROFILING; GENETICS; METABOLISM; MIDDLE AGED; PROCEDURES; PROTEIN MICROARRAY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY; TESTIS;

ADULT; AZOOSPERMIA; FEASIBILITY STUDIES; GENE EXPRESSION PROFILING; HUMANS; MALE; MIDDLE AGED; NEOPLASM PROTEINS; PROTEIN ARRAY ANALYSIS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; TESTIS; TUMOR MARKERS, BIOLOGICAL;

EID: 84888419802     PISSN: 00150282     EISSN: 15565653     Source Type: Journal    
DOI: 10.1016/j.fertnstert.2013.07.1999     Document Type: Article

References (42)

1. A. Hamada, S.C. Esteves, M. Nizza, and A. Agarwal Unexplained male infertility: diagnosis and management Int Braz J Urol 38 2012 576 594
2. E. Nieschlag Scope and goals of andrology E. Nieschlag, M.B. Behre, S. Nieschlag, Andrology: male reproductive health and dysfunction 3rd ed. 2010 Springer-Verlag Berlin 1 10
3. R. Oates Evaluation of the azoospermic male Asian J Androl 14 2012 82 87
4. H.C. King, and A.A. Sinha Gene expression profile analysis by DNA microarrays: promise and pitfalls JAMA 286 2001 2280 2288
5. M.S. Fox, V.X. Ares, P.J. Turek, C. Haqq, and R.A. Reijo Pera Feasibility of global gene expression analysis in testicular biopsies from infertile men Mol Reprod Dev 66 2003 403 421
6. J.C. Rockett, P. Patrizio, J.E. Schmid, N.B. Hecht, and D.J. Dix Gene expression patterns associated with infertility in humans and rodent models Mutat Res 549 2004 225 240
7. Y.H. Lin, Y.M. Lin, Y.N. Teng, T.Y. Hsieh, Y.S. Lin, and P.L. Kuo Identification of ten novel genes involved in human spermatogenesis by microarray analysis of testicular tissue Fertil Steril 86 2006 1650 1658
8. C. Feig, C. Kirchhoff, R. Ivell, O. Naether, W. Schulze, and A.N. Spiess A new paradigm for profiling testicular gene expression during normal and disturbed human spermatogenesis Mol Hum Reprod 13 2007 33 43
9. P.J. Ellis, R.A. Furlong, S.J. Conner, J. Kirkman-Brown, M. Afnan, and C. Barratt Coordinated transcriptional regulation patterns associated with infertility phenotypes in men J Med Genet 44 2007 498 508
10. A.N. Spiess, C. Feig, W. Schulze, F. Chalmel, H. Cappallo-Obermann, and M. Primig Cross-platform gene expression signature of human spermatogenic failure reveals inflammatory-like response Hum Reprod 22 2007 2936 2946
11. H. Wang, Z. Zhou, M. Xu, J. Li, J. Xiao, and Z.Y. Xu A spermatogenesis-related gene expression profile in human spermatozoa and its potential clinical applications J Mol Med 82 2004 317 324
12. A.E. Platts, D.J. Dix, H.E. Chemes, K.E. Thompson, R. Goodrich, and J.C. Rockett Success and failure in human spermatogenesis as revealed by teratozoospermic RNAs Hum Mol Genet 16 2007 763 773
13. N. Garrido, J.A. Martínez-Conejero, J. Jaurequi, J.A. Horcajadas, C. Simón, and J. Remohí Microarray analysis in sperm from fertility and infertile men without basic sperm analysis abnormalities reveals a significantly different transcriptome Fertil Steril 91 2009 1307 1310
14. D. Montjean, P. De La Grange, D. Gentien, A. Rapinat, S. Belloc, and P. Cohen-Bacrie Sperm transcriptome profiling in oligozoospermia J Assist Reprod Genet 29 2012 3 10
15. R.C. Gentleman, V.J. Carey, D.M. Bates, B. Bolstad, M. Dettling, and S. Dudoit Bioconductor: open software development for computational biology and bioinformatics Genome Biol 5 2004 R80
16. R.A. Irizarry, B. Hobbs, F. Collin, Y.D. Beazer-Barclay, K.J. Antonellis, and U. Scherf Exploration, normalization, and summaries of high density oligonucleotide array probe level data Biostatistics 4 2003 249 264
17. L.J. Cheng, J.M. Li, J. Chen, Y.H. Ge, Z.R. Yu, and D.S. Han NYD-SP16, a novel gene associated with spermatogenesis of human testis Biol Reprod 68 2003 190 198
18. V. Gatta, F. Raicu, A. Ferlin, I. Antonucci, A.P. Scioletti, and A. Garolla Testis transcriptome analysis in male infertility: new insight on the pathogenesis of oligo-azoospermia in cases with and without AZFc microdeletion BMC Genomics 11 2010 401
19. I.F. Ghalayini, M.A. Al-Ghazo, O.B. Hani, R. Al-Azab, I. Bani-Hani, and F. Zayed Clinical comparison of conventional testicular sperm extraction and microdissection techniques for non-obstructive azoospermia J Clin Med Res 3 2011 124 131
20. A. Abdel Raheem, G. Garaffa, N. Rushwan, F. De Luca, E. Zacharakis, and T.A. Raheem Testicular histopathology as a predictor of a positive sperm retrieval in men with non-obstructive azoospermia BJU Int 111 2013 492 499
21. L. Thomas Retrospective power analysis Conserv Biol 11 1997 276 280
22. D. Conklin, S. Holderman, T.E. Whitmore, M. Maurer, and A.L. Feldhaus Molecular cloning, chromosome mapping and characterization of UBQLN3 a testis-specific gene that contains an ubiquitin-like domain Gene 249 2000 91 98
23. A.I. Agoulnik, B. Lu, Q. Zhu, C. Truong, M.T. Ty, and N. Arango A novel gene, Pog, is necessary for primordial germ cell proliferation in the mouse and underlies the germ cell deficient mutation, gcd Hum Mol Genet 11 2002 3047 3053
24. D. Jamsai, D.M. Bianco, S.J. Smith, D.J. Merriner, J.D. Ly-Huynh, and A. Herlihy Characterization of gametogenetin 1 (GGN1) and its potential role in male fertility through the interaction with the ion channel regulator, cysteine-rich secretory protein 2 (CRISP2) in the sperm tail Reproduction 135 2008 751 759
25. D. Jamsai, M.A. Sarraj, D.J. Merriner, A.E. Drummond, K.T. Jones, and R.I. McLachlan GGN1 in the testis and ovary and its variance within the Australian fertile and infertile male population Int J Androl 34 2011 624 632
26. T.N. Dear, A. Möller, and T. Boehm CAPN11: a calpain with high mRNA levels in testis and located on chromosome 6 Genomics 59 1999 243 247
27. I. Ben-Aharon, P.R. Brown, R. Shalgi, and E.M. Eddy Calpain 11 is unique to mouse spermatogenic cells Mol Reprod Dev 73 2006 767 773
28. J. Shetty, M.J. Wolkowicz, L.C. Digilio, K.L. Klotz, F.L. Jayes, and A.B. Diekman SAMP14, a novel, acrosomal membrane-associated, glycosylphosphatidylinositol-anchored member of the Ly-6/urokinase-type plasminogen activator receptor superfamily with a role in sperm-egg interaction J Biol Chem 278 2003 30506 30515
29. H.M. Yang, G. Liu, Z.Y. Nie, D.S. Nie, Y. Deng, and G.X. Lu Molecular cloning of a novel rat gene Tsarg1, a member of the DnaJ/HSP40 protein family DNA Seq 16 2005 166 172
30. L. Li, G. Liu, J.J. Fu, L.Y. Li, X.J. Tan, and S. Yang Molecular cloning and characterization of a novel transcript variant of Mtsarg1 gene Mol Biol Rep 36 2009 1023 1032
31. B. Tubb, D.J. Mulholland, W. Vogl, Z.J. Lan, C. Niederberger, and A. Cooney Testis fascin (FSCN3): a novel paralog of the actin-bundling protein fascin expressed specifically in the elongate spermatid head Exp Cell Res 275 2002 92 109
32. S. Kollers, A. Day, and D. Rocha Characterization of the porcine FSCN3 gene: cDNA cloning, genomic structure, mapping and polymorphisms Cytogenet Genome Res 115 2006 189 192
33. H.S. Choi, S.H. Lee, H. Kim, and Y. Lee Germ cell-specific gene 1 targets testis-specific poly(A) polymerase to the endoplasmic reticulum through protein-protein interactions FEBS Lett 582 2008 1203 1209
34. S. Tate, K. Nakamura, C. Suzuki, T. Noda, J. Lee, and H. Harayama Evidence of the existence of adenylyl cyclase 10 (ADCY10) ortholog proteins in the heads and connecting pieces of boar spermatozoa J Reprod Dev 56 2010 271 278
35. L. Visser, G.H. Westerveld, F. Xie, S.K. van Daalen, F. van der Veen, and M.P. Lombardi A comprehensive gene mutation screen in men with asthenozoospermia Fertil Steril 95 2011 1020 1024
36. H. Zhang, H. Zhang, Y. Zhang, S.S. Ng, F. Ren, and Y. Wang Dishevelled-DEP domain interacting protein (DDIP) inhibits Wnt signaling by promoting TCF4 degradation and disrupting the TCF4/beta-catenin complex Cell Signal 22 2010 1753 1760
37. T.N. Dear, and T. Boehm Diverse mRNA expression patterns of the mouse calpain genes Capn5, Capn6 and Capn11 during development Mech Dev 89 1999 201 209
38. Q. Zhao, Y. Zhou, Z. Cao, H. Zhu, P. Huang, and B. Lu Germ-cell specific protein gametogenetin protein 2 (GGN2), expression in the testis, and association with intracellular membrane Mol Reprod Dev 72 2005 31 39
39. S. Yang, W. Wang, C. Lei, Q. Liu, F. Xu, and X. Xing Localization and characterization of rat transmembrane protein 225 specifically expressed in testis DNA Cell Biol 30 2011 9 16
40. C.A. Capoano, R. Wettstein, A. Kun, and A. Geisinger Spats 1 (Srsp1) is differentially expressed during testis development of the rat Gene Expr Patterns 10 2010 1 8
41. H. Tanaka, Y. Yoshimura, Y. Nishina, M. Nozaki, H. Nojima, and Y. Nishimune Isolation and characterization of cDNA clones specifically expressed in testicular germ cells FEBS Lett 355 1994 4 10
42. F. Xie, and M. Conti Expression of the soluble adenylyl cyclase during rat spermatogenesis: evidence for cytoplasmic sites of cAMP production in germ cells Dev Biol 265 2004 196 206