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Volumn 25, Issue 10, 2013, Pages 4110-4122

Morphine biosynthesis in opium poppy involves two cell types: Sieve elements and laticifers

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Indexed keywords

PAPAVER SOMNIFERUM;

EID: 84888399274     PISSN: 10404651     EISSN: 1532298X     Source Type: Journal    
DOI: 10.1105/tpc.113.115113     Document Type: Article
Times cited : (76)

References (59)
  • 1
    • 26844450886 scopus 로고    scopus 로고
    • Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment
    • Alcantara, J., Bird, D.A., Francheschi, V.R., and Facchini, P.J. (2005). Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment. Plant Physiol. 138: 173-183.
    • (2005) Plant Physiol. , vol.138 , pp. 173-183
    • Alcantara, J.1    Bird, D.A.2    Francheschi, V.R.3    Facchini, P.J.4
  • 2
    • 0345376982 scopus 로고    scopus 로고
    • A tale of three cell types: Alkaloid biosynthesis is localized to sieve elements in opium poppy
    • Bird, D.A., Franceschi, V.R., and Facchini, P.J. (2003). A tale of three cell types: Alkaloid biosynthesis is localized to sieve elements in opium poppy. Plant Cell 15: 2626-2635.
    • (2003) Plant Cell , vol.15 , pp. 2626-2635
    • Bird, D.A.1    Franceschi, V.R.2    Facchini, P.J.3
  • 3
    • 0021123010 scopus 로고
    • A second pathway for the terminal steps in the biosynthesis of morphine
    • Brochmann-Hanssen, E. (1984). A second pathway for the terminal steps in the biosynthesis of morphine. Planta Med. 50: 343-345.
    • (1984) Planta Med. , vol.50 , pp. 343-345
    • Brochmann-Hanssen, E.1
  • 6
    • 84861878374 scopus 로고    scopus 로고
    • Characterization of three O-methyltransferases involved in noscapine biosynthesis in opium poppy
    • Dang, T.T.T., and Facchini, P.J. (2012). Characterization of three O-methyltransferases involved in noscapine biosynthesis in opium poppy. Plant Physiol. 159: 618-631.
    • (2012) Plant Physiol. , vol.159 , pp. 618-631
    • Dang, T.T.T.1    Facchini, P.J.2
  • 7
    • 0033769358 scopus 로고    scopus 로고
    • Characterization of proteins in latex of the opium poppy (Papaver somniferum) using two-dimensional gel electrophoresis and microsequencing
    • Decker, G., Wanner, G., Zenk, M.H., and Lottspeich, F. (2000). Characterization of proteins in latex of the opium poppy (Papaver somniferum) using two-dimensional gel electrophoresis and microsequencing. Electrophoresis 21: 3500-3516.
    • (2000) Electrophoresis. , vol.21 , pp. 3500-3516
    • Decker, G.1    Wanner, G.2    Zenk, M.H.3    Lottspeich, F.4
  • 8
    • 20344383308 scopus 로고
    • Purification and properties of 1,2-dehydroreticuline reductase from Papaver somniferum seedlings
    • DeEknamkul, W., and Zenk, M.H. (1992). Purification and properties of 1,2-dehydroreticuline reductase from Papaver somniferum seedlings. Phytochemistry 31: 813-821.
    • (1992) Phytochemistry. , vol.31 , pp. 813-821
    • DeEknamkul, W.1    Zenk, M.H.2
  • 9
    • 84867576863 scopus 로고    scopus 로고
    • Systematic silencing of benzylisoquinoline alkaloid biosynthetic genes reveals the major route to papaverine in opium poppy
    • Desgagné-Penix, I., and Facchini, P.J. (2012). Systematic silencing of benzylisoquinoline alkaloid biosynthetic genes reveals the major route to papaverine in opium poppy. Plant J. 72: 331-344.
    • (2012) Plant J. , vol.72 , pp. 331-344
    • Desgagné-Penix, I.1    Facchini, P.J.2
  • 10
    • 84860840868 scopus 로고    scopus 로고
    • Integration of deep transcript and targeted metabolite profiles for eight cultivars of opium poppy
    • Desgagné-Penix, I., Farrow, S.C., Cram, D., Nowak, J., and Facchini, P.J. (2012). Integration of deep transcript and targeted metabolite profiles for eight cultivars of opium poppy. Plant Mol. Biol. 79: 295-313.
    • (2012) Plant Mol. Biol. , vol.79 , pp. 295-313
    • Desgagné-Penix, I.1    Farrow, S.C.2    Cram, D.3    Nowak, J.4    Facchini, P.J.5
  • 11
    • 78349297591 scopus 로고    scopus 로고
    • Integration of deep transcriptome and proteome analysis reveals the components of alkaloid metabolism in opium poppy cell cultures
    • Desgagné-Penix, I., Khan, M.F., Schriemer, D.C., Cram, D., Nowak, J., and Facchini, P.J. (2010). Integration of deep transcriptome and proteome analysis reveals the components of alkaloid metabolism in opium poppy cell cultures. BMC Plant Biol. 10: 252.
    • (2010) BMC Plant Biol. , vol.10 , pp. 252
    • Desgagné-Penix, I.1    Khan, M.F.2    Schriemer, D.C.3    Cram, D.4    Nowak, J.5    Facchini, P.J.6
  • 13
    • 79951562237 scopus 로고    scopus 로고
    • Characterization of two methylenedioxy bridge-forming cytochrome P450-dependent enzymes of alkaloid formation in the Mexican prickly poppy Argemone mexicana
    • Díaz Chávez, M.L., Rolf, M., Gesell, A., and Kutchan, T.M. (2011). Characterization of two methylenedioxy bridge-forming cytochrome P450-dependent enzymes of alkaloid formation in the Mexican prickly poppy Argemone mexicana. Arch. Biochem. Biophys. 507: 186-193.
    • (2011) Arch. Biochem. Biophys. , vol.507 , pp. 186-193
    • Díaz Chávez, M.L.1    Rolf, M.2    Gesell, A.3    Kutchan, T.M.4
  • 14
    • 0001160483 scopus 로고
    • The alkaloids of Papaver somniferum L.-III. Biosynthesis in the isolated latex
    • Fairbairn, J.W., and Wassel, G. (1964). The alkaloids of Papaver somniferum L.-III. Biosynthesis in the isolated latex. Phytochemistry 3: 583-585.
    • (1964) Phytochemistry. , vol.3 , pp. 583-585
    • Fairbairn, J.W.1    Wassel, G.2
  • 15
    • 43549115911 scopus 로고    scopus 로고
    • Opium poppy and Madagascar periwinkle: Model non-model systems to investigate alkaloid biosynthesis in plants
    • Facchini, P.J., and De Luca, V. (2008). Opium poppy and Madagascar periwinkle: Model non-model systems to investigate alkaloid biosynthesis in plants. Plant J. 54: 763-784.
    • (2008) Plant J. , vol.54 , pp. 763-784
    • Facchini, P.J.1    De Luca, V.2
  • 16
    • 0042823501 scopus 로고    scopus 로고
    • Developmental and inducible accumulation of gene transcripts involved in alkaloid biosynthesis in opium poppy
    • Facchini, P.J., and Park, S.U. (2003). Developmental and inducible accumulation of gene transcripts involved in alkaloid biosynthesis in opium poppy. Phytochemistry 64: 177-186.
    • (2003) Phytochemistry. , vol.64 , pp. 177-186
    • Facchini, P.J.1    Park, S.U.2
  • 17
    • 0030468681 scopus 로고    scopus 로고
    • Molecular characterization of berberine bridge enzyme genes from opium poppy
    • Facchini, P.J., Penzes, C., Johnson, A.G., and Bull, D. (1996). Molecular characterization of berberine bridge enzyme genes from opium poppy. Plant Physiol. 112: 1669-1677.
    • (1996) Plant Physiol. , vol.112 , pp. 1669-1677
    • Facchini, P.J.1    Penzes, C.2    Johnson, A.G.3    Bull, D.4
  • 18
    • 84859159395 scopus 로고    scopus 로고
    • Transcript and metabolite profiling in cell cultures of 18 plant species that produce benzylisoquinoline alkaloids
    • Farrow, S.C., Hagel, J.M., and Facchini, P.J. (2012). Transcript and metabolite profiling in cell cultures of 18 plant species that produce benzylisoquinoline alkaloids. Phytochemistry 77: 79-88.
    • (2012) Phytochemistry. , vol.77 , pp. 79-88
    • Farrow, S.C.1    Hagel, J.M.2    Facchini, P.J.3
  • 19
    • 69949174213 scopus 로고    scopus 로고
    • CYP719B1 is salutaridine synthase, the C-C phenol-coupling enzyme of morphine biosynthesis in opium poppy
    • Gesell, A., Rolf, M., Ziegler, J., Díaz Chávez, M.L., Huang, F.C., and Kutchan, T.M. (2009). CYP719B1 is salutaridine synthase, the C-C phenol-coupling enzyme of morphine biosynthesis in opium poppy. J. Biol. Chem. 284: 24432-24442.
    • (2009) J. Biol. Chem. , vol.284 , pp. 24432-24442
    • Gesell, A.1    Rolf, M.2    Ziegler, J.3    Díaz Chávez, M.L.4    Huang, F.C.5    Kutchan, T.M.6
  • 20
    • 85017282120 scopus 로고
    • Immunolocalization of the major latex proteins in developing laticifers of opium poppy (Papaver somniferum)
    • Griffing, L.R., and Nessler, C.L. (1988). Immunolocalization of the major latex proteins in developing laticifers of opium poppy (Papaver somniferum). J. Plant Physiol. 134: 357-363.
    • (1988) J. Plant Physiol. , vol.134 , pp. 357-363
    • Griffing, L.R.1    Nessler, C.L.2
  • 22
    • 0035903228 scopus 로고    scopus 로고
    • Molecular characterization of the salutaridinol 7-O-acetyltransferase involved in morphine biosynthesis in opium poppy Papaver somniferum
    • Grothe, T., Lenz, R., and Kutchan, T.M. (2001). Molecular characterization of the salutaridinol 7-O-acetyltransferase involved in morphine biosynthesis in opium poppy Papaver somniferum. J. Biol. Chem. 276: 30717-30723.
    • (2001) J. Biol. Chem. , vol.276 , pp. 30717-30723
    • Grothe, T.1    Lenz, R.2    Kutchan, T.M.3
  • 23
    • 77949847651 scopus 로고    scopus 로고
    • Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy
    • Hagel, J.M., and Facchini, P.J. (2010). Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy. Nat. Chem. Biol. 6: 273-275.
    • (2010) Nat. Chem. Biol. , vol.6 , pp. 273-275
    • Hagel, J.M.1    Facchini, P.J.2
  • 24
    • 84878001183 scopus 로고    scopus 로고
    • Benzylisoquinoline alkaloid metabolism: A century of discovery and a brave new world
    • Hagel, J.M., and Facchini, P.J. (2013). Benzylisoquinoline alkaloid metabolism: A century of discovery and a brave new world. Plant Cell Physiol. 54: 647-672.
    • (2013) Plant Cell Physiol. , vol.54 , pp. 647-672
    • Hagel, J.M.1    Facchini, P.J.2
  • 26
    • 26844559000 scopus 로고    scopus 로고
    • Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein
    • Ishihama, Y., Oda, Y., Tabata, T., Sato, T., Nagasu, T., Rappsilber, J., and Mann, M. (2005). Exponentially modified protein abundance index (emPAI) for estimation of absolute protein amount in proteomics by the number of sequenced peptides per protein. Mol. Cell. Proteomics 4: 13256-13272.
    • (2005) Mol. Cell. Proteomics. , vol.4 , pp. 13256-13272
    • Ishihama, Y.1    Oda, Y.2    Tabata, T.3    Sato, T.4    Nagasu, T.5    Rappsilber, J.6    Mann, M.7
  • 27
    • 64949176017 scopus 로고    scopus 로고
    • RNAi suppression of the morphine biosynthetic gene salAT and evidence of association of pathway enzymes
    • Kempe, K., Higashi, Y., Frick, S., Sabarna, K., and Kutchan, T.M. (2009). RNAi suppression of the morphine biosynthetic gene salAT and evidence of association of pathway enzymes. Phytochemistry 70: 579-589.
    • (2009) Phytochemistry. , vol.70 , pp. 579-589
    • Kempe, K.1    Higashi, Y.2    Frick, S.3    Sabarna, K.4    Kutchan, T.M.5
  • 28
    • 0014201273 scopus 로고
    • Biosynthesis of morphine alkaloids
    • Kirby, G.W. (1967). Biosynthesis of morphine alkaloids. Science 155: 170-173.
    • (1967) Science. , vol.155 , pp. 170-173
    • Kirby, G.W.1
  • 29
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U.K. (1970). Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature 227: 680-685.
    • (1970) Nature. , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 30
    • 78649499936 scopus 로고    scopus 로고
    • Norcoclaurine synthase is a member of the pathogenesis-related 10/Bet v1 protein family
    • Lee, E.-J., and Facchini, P.J. (2010). Norcoclaurine synthase is a member of the pathogenesis-related 10/Bet v1 protein family. Plant Cell 22: 3489-3503.
    • (2010) Plant Cell , vol.22 , pp. 3489-3503
    • Lee, E.-J.1    Facchini, P.J.2
  • 31
    • 0029559296 scopus 로고
    • Acetyl coenzyme A:Salutaridinol-7-O-acetyltransferase from Papaver somniferum plant cell cultures. The enzyme catalyzing the formation of thebaine in morphine biosynthesis
    • Lenz, R., and Zenk, M.H. (1995). Acetyl coenzyme A:salutaridinol-7-O-acetyltransferase from Papaver somniferum plant cell cultures. The enzyme catalyzing the formation of thebaine in morphine biosynthesis. J. Biol. Chem. 270: 31091-31096.
    • (1995) J. Biol. Chem. , vol.270 , pp. 31091-31096
    • Lenz, R.1    Zenk, M.H.2
  • 32
    • 34447529465 scopus 로고    scopus 로고
    • Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy
    • Liscombe, D.K., and Facchini, P.J. (2007). Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy. J. Biol. Chem. 282: 14741-14751.
    • (2007) J. Biol. Chem. , vol.282 , pp. 14741-14751
    • Liscombe, D.K.1    Facchini, P.J.2
  • 33
    • 20444396193 scopus 로고    scopus 로고
    • Evidence for the monophyletic evolution of benzylisoquinoline alkaloid biosynthesis in angiosperms
    • Liscombe, D.K., MacLeod, B.P., Loukanina, N., Nandi, O.I., and Facchini, P.J. (2005). Evidence for the monophyletic evolution of benzylisoquinoline alkaloid biosynthesis in angiosperms. Phytochemistry 66: 2501-2520.
    • (2005) Phytochemistry. , vol.66 , pp. 2501-2520
    • Liscombe, D.K.1    McLeod, B.P.2    Loukanina, N.3    Nandi, O.I.4    Facchini, P.J.5
  • 34
    • 72449148338 scopus 로고    scopus 로고
    • Targeted metabolite and transcript profiling for elucidating enzyme function: Isolation of novel N-methyltransferases from three benzylisoquinoline alkaloid-producing species
    • Liscombe, D.K., Ziegler, J., Schmidt, J., Ammer, C., and Facchini, P.J. (2009). Targeted metabolite and transcript profiling for elucidating enzyme function: isolation of novel N-methyltransferases from three benzylisoquinoline alkaloid-producing species. Plant J. 60: 729-743.
    • (2009) Plant J. , vol.60 , pp. 729-743
    • Liscombe, D.K.1    Ziegler, J.2    Schmidt, J.3    Ammer, C.4    Facchini, P.J.5
  • 35
    • 34249935508 scopus 로고    scopus 로고
    • Proteomic analysis of Chelidonium majus sap using two-dimensional gel electrophoresis and tandem mass spectrometry
    • Nawrot, R., Kalinowski, A., and Gozdzicka-Jozefiak, A. (2007). Proteomic analysis of Chelidonium majus sap using two-dimensional gel electrophoresis and tandem mass spectrometry. Phytochemistry 68: 1612-1622.
    • (2007) Phytochemistry. , vol.68 , pp. 1612-1622
    • Nawrot, R.1    Kalinowski, A.2    Gozdzicka-Jozefiak, A.3
  • 36
    • 28544434112 scopus 로고    scopus 로고
    • Characterization of vacuolar transport of the endogenous alkaloid berberine in Coptis japonica
    • Otani, M., Shitan, N., Sakai, K., Martinoia, E., Sato, F., and Yazaki, K. (2005). Characterization of vacuolar transport of the endogenous alkaloid berberine in Coptis japonica. Plant Physiol. 138: 1939-1946.
    • (2005) Plant Physiol. , vol.138 , pp. 1939-1946
    • Otani, M.1    Shitan, N.2    Sakai, K.3    Martinoia, E.4    Sato, F.5    Yazaki, K.6
  • 37
    • 0347317979 scopus 로고    scopus 로고
    • (R, S)-Reticuline 7-O-methyltransferase and (R, S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum-cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy
    • Ounaroon, A., Decker, G., Schmidt, J., Lottspeich, F., and Kutchan, T.M. (2003). (R, S)-Reticuline 7-O-methyltransferase and (R, S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum-cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy. Plant J. 36: 808-819.
    • (2003) Plant J. , vol.36 , pp. 808-819
    • Ounaroon, A.1    Decker, G.2    Schmidt, J.3    Lottspeich, F.4    Kutchan, T.M.5
  • 38
    • 79955574643 scopus 로고    scopus 로고
    • Convergent evolution in plant specialized metabolism
    • Pichersky, E., and Lewinsohn, E. (2011). Convergent evolution in plant specialized metabolism. Annu. Rev. Plant Biol. 62: 549-566.
    • (2011) Annu. Rev. Plant Biol. , vol.62 , pp. 549-566
    • Pichersky, E.1    Lewinsohn, E.2
  • 39
    • 70349499351 scopus 로고    scopus 로고
    • Functional characterization of a novel benzylisoquinoline-Omethyltransferase suggests its involvement in papaverine biosynthesis in opium poppy (Papaver somniferum L)
    • Pienkny, S., Brandt, W., Schmidt, J., Kramell, R., and Ziegler, J. (2009). Functional characterization of a novel benzylisoquinoline-Omethyltransferase suggests its involvement in papaverine biosynthesis in opium poppy (Papaver somniferum L). Plant J. 60: 56-67.
    • (2009) Plant J. , vol.60 , pp. 56-67
    • Pienkny, S.1    Brandt, W.2    Schmidt, J.3    Kramell, R.4    Ziegler, J.5
  • 41
    • 33746489315 scopus 로고    scopus 로고
    • Role of sieve elements and laticifers in the biosynthesis of accumulation of alkaloids in opium poppy
    • Samanani, N., Alcantara, J., Bourgault, R., Zulak, K.G., and Facchini, P.J. (2006). Role of sieve elements and laticifers in the biosynthesis of accumulation of alkaloids in opium poppy. Plant J. 47: 547-564.
    • (2006) Plant J. , vol.47 , pp. 547-564
    • Samanani, N.1    Alcantara, J.2    Bourgault, R.3    Zulak, K.G.4    Facchini, P.J.5
  • 42
    • 6444243887 scopus 로고    scopus 로고
    • Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis
    • Samanani, N., Liscombe, D.K., and Facchini, P.J. (2004). Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis. Plant J. 40: 302-313.
    • (2004) Plant J. , vol.40 , pp. 302-313
    • Samanani, N.1    Liscombe, D.K.2    Facchini, P.J.3
  • 43
    • 1842499791 scopus 로고    scopus 로고
    • Profiling core proteomes of human cell lines by one-dimensional PAGE and liquid chromatography-tandem mass spectrometry
    • Schirle, M., Heurtier, M.-A., and Kuster, B. (2003). Profiling core proteomes of human cell lines by one-dimensional PAGE and liquid chromatography-tandem mass spectrometry. Mol. Cell. Proteomics 2: 1297-1305.
    • (2003) Mol. Cell. Proteomics. , vol.2 , pp. 1297-1305
    • Schirle, M.1    Heurtier, M.-A.2    Kuster, B.3
  • 44
    • 77949518999 scopus 로고    scopus 로고
    • emPAI-Calc-For the estimation of protein abundance from large-scale identification data by liquid chromatography-tandem mass spectrometry
    • Shinoda, K., Tomita, M., and Ishihama, Y. (2009). emPAI-Calc-For the estimation of protein abundance from large-scale identification data by liquid chromatography-tandem mass spectrometry. Bioinformatics 26: 576-577.
    • (2009) Bioinformatics. , vol.26 , pp. 576-577
    • Shinoda, K.1    Tomita, M.2    Ishihama, Y.3
  • 45
    • 0037457993 scopus 로고    scopus 로고
    • Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica
    • Shitan, N., Bazin, I., Dan, K., Obata, K., Kigawa, K., Ueda, K., Sato, F., Forestier, C., and Yazaki, K. (2003). Involvement of CjMDR1, a plant multidrug-resistance-type ATP-binding cassette protein, in alkaloid transport in Coptis japonica. Proc. Natl. Acad. Sci. USA 100: 751-756.
    • (2003) Proc. Natl. Acad. Sci. USA. , vol.100 , pp. 751-756
    • Shitan, N.1    Bazin, I.2    Dan, K.3    Obata, K.4    Kigawa, K.5    Ueda, K.6    Sato, F.7    Forestier, C.8    Yazaki, K.9
  • 47
    • 0004671501 scopus 로고
    • O-demethylation as a biosynthetic pattern in the formation of opium alkaloids
    • Stermitz, F.R., and Rapoport, H. (1961). O-demethylation as a biosynthetic pattern in the formation of opium alkaloids. Nature 189: 310-311.
    • (1961) Nature. , vol.189 , pp. 310-311
    • Stermitz, F.R.1    Rapoport, H.2
  • 48
    • 0033152629 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of codeinone reductase: The penultimate enzyme in morphine biosynthesis in the opium poppy Papaver somniferum
    • Unterlinner, B., Lenz, R., and Kutchan, T.M. (1999). Molecular cloning and functional expression of codeinone reductase: The penultimate enzyme in morphine biosynthesis in the opium poppy Papaver somniferum. Plant J. 18: 465-475.
    • (1999) Plant J. , vol.18 , pp. 465-475
    • Unterlinner, B.1    Lenz, R.2    Kutchan, T.M.3
  • 49
    • 84863633005 scopus 로고    scopus 로고
    • Tissue proteomics by one-dimensional gel electrophoresis combined with label-free protein quantification
    • Vasilj, A., Gentzel, M., Ueberham, E., Gebhardt, R., and Shevchenko, A. (2012). Tissue proteomics by one-dimensional gel electrophoresis combined with label-free protein quantification. J. Proteome Res. 11: 3680-3689.
    • (2012) J. Proteome Res. , vol.11 , pp. 3680-3689
    • Vasilj, A.1    Gentzel, M.2    Ueberham, E.3    Gebhardt, R.4    Shevchenko, A.5
  • 50
    • 0141872961 scopus 로고    scopus 로고
    • Towards deciphering phloem: A transcriptome analysis of the phloem of Apium graveolens
    • Vilaine, F., Palauqui, J.C., Amselem, J., Kusiak, C., Lemoine, R., and Dinant, S. (2003). Towards deciphering phloem: A transcriptome analysis of the phloem of Apium graveolens. Plant J. 36: 67-81.
    • (2003) Plant J. , vol.36 , pp. 67-81
    • Vilaine, F.1    Palauqui, J.C.2    Amselem, J.3    Kusiak, C.4    Lemoine, R.5    Dinant, S.6
  • 51
    • 77953305612 scopus 로고    scopus 로고
    • Structure and mechanism of sanguinarine reductase, an enzyme of alkaloid detoxification
    • Vogel, M., Lawson, M., Sippl, W., Conrad, U., and Roos, W. (2010). Structure and mechanism of sanguinarine reductase, an enzyme of alkaloid detoxification. J. Biol. Chem. 285: 18397-18406.
    • (2010) J. Biol. Chem. , vol.285 , pp. 18397-18406
    • Vogel, M.1    Lawson, M.2    Sippl, W.3    Conrad, U.4    Roos, W.5
  • 53
    • 3242773051 scopus 로고    scopus 로고
    • Proteomics of curcurbit phloem exudate reveals a network of defence proteins
    • Walz, C., Giavalisco, P., Schad, M., Juenger, M., Klose, J., and Kehr, J. (2004). Proteomics of curcurbit phloem exudate reveals a network of defence proteins. Phytochemistry 65: 1795-1804.
    • (2004) Phytochemistry. , vol.65 , pp. 1795-1804
    • Walz, C.1    Giavalisco, P.2    Schad, M.3    Juenger, M.4    Klose, J.5    Kehr, J.6
  • 54
    • 4644289320 scopus 로고    scopus 로고
    • The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum
    • Weid, M., Ziegler, J., and Kutchan, T.M. (2004). The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaver somniferum. Proc. Natl. Acad. Sci. USA 101: 13957-13962.
    • (2004) Proc. Natl. Acad. Sci. USA. , vol.101 , pp. 13957-13962
    • Weid, M.1    Ziegler, J.2    Kutchan, T.M.3
  • 55
    • 84862983375 scopus 로고    scopus 로고
    • A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine
    • Winzer, T., et al. (2012). A Papaver somniferum 10-gene cluster for synthesis of the anticancer alkaloid noscapine. Science 336: 1704-1708.
    • (2012) Science. , vol.336 , pp. 1704-1708
    • Winzer, T.1
  • 57
    • 26644468125 scopus 로고    scopus 로고
    • Comparative macroarray analysis of morphine containing Papaver somniferum and eight morphine free Papaver species identifies an O-methyltransferase involved in benzylisoquinoline biosynthesis
    • Ziegler, J., Diaz Chávez, M.L., Kramell, R., Ammer, C., and Kutchan, T.M. (2005). Comparative macroarray analysis of morphine containing Papaver somniferum and eight morphine free Papaver species identifies an O-methyltransferase involved in benzylisoquinoline biosynthesis. Planta 222: 458-471.
    • (2005) Planta. , vol.222 , pp. 458-471
    • Ziegler, J.1    Diaz Chávez, M.L.2    Kramell, R.3    Ammer, C.4    Kutchan, T.M.5
  • 58
    • 33749241876 scopus 로고    scopus 로고
    • Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis
    • Ziegler, J., Voigtländer, S., Schmidt, J., Kramell, R., Miersch, O., Ammer, C., Gesell, A., and Kutchan, T.M. (2006). Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis. Plant J. 48: 177-192.
    • (2006) Plant J. , vol.48 , pp. 177-192
    • Ziegler, J.1    Voigtländer, S.2    Schmidt, J.3    Kramell, R.4    Miersch, O.5    Ammer, C.6    Gesell, A.7    Kutchan, T.M.8
  • 59
    • 59149089086 scopus 로고    scopus 로고
    • Plant defense responses in opium poppy cell cultures revealed by liquid chromatography-tandem mass spectrometry proteomics
    • Zulak, K.G., Khan, M.F., Alcantara, J., Schriemer, D.C., and Facchini, P.J. (2009). Plant defense responses in opium poppy cell cultures revealed by liquid chromatography-tandem mass spectrometry proteomics. Mol. Cell. Proteomics 8: 86-98.
    • (2009) Mol. Cell. Proteomics. , vol.8 , pp. 86-98
    • Zulak, K.G.1    Khan, M.F.2    Alcantara, J.3    Schriemer, D.C.4    Facchini, P.J.5


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