메뉴 건너뛰기




Volumn 79, Issue 3, 2012, Pages 295-313

Integration of deep transcript and targeted metabolite profiles for eight cultivars of opium poppy

Author keywords

454 Pyrosequencing; Benzylisoquinoline alkaloids; Metabolite profiling; Opium poppy; Transcriptomics

Indexed keywords

BENZYLISOQUINOLINE DERIVATIVE;

EID: 84860840868     PISSN: 01674412     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11103-012-9913-2     Document Type: Article
Times cited : (68)

References (97)
  • 2
    • 26844450886 scopus 로고    scopus 로고
    • Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment
    • Alcantara J, Bird DA, Franceschi VR, Facchini PJ (2005) Sanguinarine biosynthesis is associated with the endoplasmic reticulum in cultured opium poppy cells after elicitor treatment. Plant Physiol 138: 173-183.
    • (2005) Plant Physiol , vol.138 , pp. 173-183
    • Alcantara, J.1    Bird, D.A.2    Franceschi, V.R.3    Facchini, P.J.4
  • 3
    • 36849084099 scopus 로고    scopus 로고
    • Metabolic engineering of morphinan alkaloids by over-expression and RNAi suppression of salutaridinol 7-O-acetyltransferase in opium poppy
    • Allen RS, Miller JA, Chitty JA, Fist AJ, Gerlach WL, Larkin PJ (2008) Metabolic engineering of morphinan alkaloids by over-expression and RNAi suppression of salutaridinol 7-O-acetyltransferase in opium poppy. Plant Biotechnol J 6: 22-30.
    • (2008) Plant Biotechnol J , vol.6 , pp. 22-30
    • Allen, R.S.1    Miller, J.A.2    Chitty, J.A.3    Fist, A.J.4    Gerlach, W.L.5    Larkin, P.J.6
  • 4
    • 0034649566 scopus 로고    scopus 로고
    • Analysis of the genome sequence of the flowering plant Arabidosisthaliana
    • Arabidopsis Genome Initiative
    • Arabidopsis Genome Initiative (2000) Analysis of the genome sequence of the flowering plant Arabidosisthaliana. Nature 408: 796-815.
    • (2000) Nature , vol.408 , pp. 796-815
  • 5
    • 67649085779 scopus 로고    scopus 로고
    • Comparison of the transcriptomes of American chestnut (Castanea dentate) and Chinese chestnut (Castanea mollissima) in response to the chestnut blight infection
    • Barakat A, DiLoreto DS, Zhang Y, Smith C, Baier K, Powel WA, Wheeler N, Sederoff R, Carlson JE (2009) Comparison of the transcriptomes of American chestnut (Castanea dentate) and Chinese chestnut (Castanea mollissima) in response to the chestnut blight infection. BMC Plant Biol 9: 51-61.
    • (2009) BMC Plant Biol , vol.9 , pp. 51-61
    • Barakat, A.1    Diloreto, D.S.2    Zhang, Y.3    Smith, C.4    Baier, K.5    Powel, W.A.6    Wheeler, N.7    Sederoff, R.8    Carlson, J.E.9
  • 6
    • 0038819412 scopus 로고    scopus 로고
    • Alkaloid accumulation in capsules of the selfed and cross-pollinated poppy
    • Bernath J, Nemeth E, Petheo F (2003) Alkaloid accumulation in capsules of the selfed and cross-pollinated poppy. Plant Breeding 122: 263-267.
    • (2003) Plant Breeding , vol.122 , pp. 263-267
    • Bernath, J.1    Nemeth, E.2    Petheo, F.3
  • 7
    • 0345376982 scopus 로고    scopus 로고
    • A tale of three cell types: alkaloid biosynthesis is localized to sieve elements in opium poppy
    • Bird DA, Franceschi VR, Facchini PJ (2003) A tale of three cell types: alkaloid biosynthesis is localized to sieve elements in opium poppy. Plant Cell 15: 2626-2635.
    • (2003) Plant Cell , vol.15 , pp. 2626-2635
    • Bird, D.A.1    Franceschi, V.R.2    Facchini, P.J.3
  • 8
    • 0017184389 scopus 로고
    • Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
    • Bradford MM (1976) Rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding. Anal Biochem 72: 248-254.
    • (1976) Anal Biochem , vol.72 , pp. 248-254
    • Bradford, M.M.1
  • 9
    • 0037016691 scopus 로고    scopus 로고
    • Molecular cloning and characterization of coclaurine N-methylatransferase from cultured cells of Coptis japonica
    • Choi KB, Morishige T, Shitan N, Yazaki K, Sato F (2002) Molecular cloning and characterization of coclaurine N-methylatransferase from cultured cells of Coptis japonica. J Biol Chem 277: 830-835.
    • (2002) J Biol Chem , vol.277 , pp. 830-835
    • Choi, K.B.1    Morishige, T.2    Shitan, N.3    Yazaki, K.4    Sato, F.5
  • 10
    • 20344383308 scopus 로고
    • Purification and properties of 1,2-dehydroreticuline reductase from Papaversomniferum seedlings
    • De-Eknamkul W, Zenk MH (1992) Purification and properties of 1, 2-dehydroreticuline reductase from Papaversomniferum seedlings. Phytochemistry 31: 813-821.
    • (1992) Phytochemistry , vol.31 , pp. 813-821
    • De-Eknamkul, W.1    Zenk, M.H.2
  • 11
    • 79960128962 scopus 로고    scopus 로고
    • Transcriptomic analysis of grain amaranth (Amaranthus hypochodiacus) using 454 pyrosequencing: comparison with A. tuberculatus, expression profiling in stems and in response to biotic and abiotic stress
    • Délano-Frier JP, Avilés-Arnaut H, Casarrubias-Castillo K, Casique-Arroyo G et al (2011) Transcriptomic analysis of grain amaranth (Amaranthus hypochodiacus) using 454 pyrosequencing: comparison with A. tuberculatus, expression profiling in stems and in response to biotic and abiotic stress. BMC Plant Biol 12: 363-380.
    • (2011) BMC Plant Biol , vol.12 , pp. 363-380
    • Délano-Frier, J.P.1    Avilés-Arnaut, H.2    Casarrubias-Castillo, K.3    Casique-Arroyo, G.4
  • 12
    • 78349297591 scopus 로고    scopus 로고
    • Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures
    • Desgagné-Penix I, Khan MF, Schriemer DC, Nowak J, Facchini PJ (2010) Integration of deep transcriptome and proteome analyses reveals the components of alkaloid metabolism in opium poppy cell cultures. BMC Plant Biol 10: 252-268.
    • (2010) BMC Plant Biol , vol.10 , pp. 252-268
    • Desgagné-Penix, I.1    Khan, M.F.2    Schriemer, D.C.3    Nowak, J.4    Facchini, P.J.5
  • 13
    • 79951562237 scopus 로고    scopus 로고
    • Characterization of two methylenedioxy bridge-forming cytochrome P450-dependent enzymes of alkaloid formation in the Mexican prickly poppy Argemone mexicana
    • Diaz-Chavez ML, Rolf M, Gesell A, Kutchan TM (2011) Characterization of two methylenedioxy bridge-forming cytochrome P450-dependent enzymes of alkaloid formation in the Mexican prickly poppy Argemone mexicana. Arch Biochem Biophys 507: 186-193.
    • (2011) Arch Biochem Biophys , vol.507 , pp. 186-193
    • Diaz-Chavez, M.L.1    Rolf, M.2    Gesell, A.3    Kutchan, T.M.4
  • 14
    • 0025751609 scopus 로고
    • Molecular cloning, expression, and induction of berberine bridge enzyme, an enzyme essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack
    • Dittrich H, Kutchan TM (1991) Molecular cloning, expression, and induction of berberine bridge enzyme, an enzyme essential to the formation of benzophenanthridine alkaloids in the response of plants to pathogenic attack. Proc Natl Acad Sci USA 88: 9969-9973.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 9969-9973
    • Dittrich, H.1    Kutchan, T.M.2
  • 15
    • 0028125304 scopus 로고
    • Differential and tissue-specific expression of a gene family for tyrosine/dopa decarboxylase in opium poppy
    • Facchini PJ, DeLuca V (1994) Differential and tissue-specific expression of a gene family for tyrosine/dopa decarboxylase in opium poppy. J Biol Chem 269: 26684-26690.
    • (1994) J Biol Chem , vol.269 , pp. 26684-26690
    • Facchini, P.J.1    Deluca, V.2
  • 16
    • 0042823501 scopus 로고    scopus 로고
    • Developmental and inducible accumulation of gene transcripts involved in alkaloid biosynthesis in opium poppy
    • Facchini PJ, Park S-U (2003) Developmental and inducible accumulation of gene transcripts involved in alkaloid biosynthesis in opium poppy. Phytochemistry 64: 177-186.
    • (2003) Phytochemistry , vol.64 , pp. 177-186
    • Facchini, P.J.1    Park, S.-U.2
  • 17
    • 0030468681 scopus 로고    scopus 로고
    • Molecular characterization of berberine bridge enzyme genes from opium poppy
    • Facchini PJ, Penzes C, Johnson AG, Bull D (1996) Molecular characterization of berberine bridge enzyme genes from opium poppy. Plant Physiol 112: 1669-1677.
    • (1996) Plant Physiol , vol.112 , pp. 1669-1677
    • Facchini, P.J.1    Penzes, C.2    Johnson, A.G.3    Bull, D.4
  • 19
    • 42249094600 scopus 로고    scopus 로고
    • Thebaine synthase: a new enzyme in the morphine pathway in Papaver somniferum
    • Fisinger U, Grobe N, Zenk MH (2006) Thebaine synthase: a new enzyme in the morphine pathway in Papaver somniferum. Nat Prod Commun 2: 249-253.
    • (2006) Nat Prod Commun , vol.2 , pp. 249-253
    • Fisinger, U.1    Grobe, N.2    Zenk, M.H.3
  • 20
    • 20444441197 scopus 로고    scopus 로고
    • Comparative qualitative and quantitative determination of alkaloids in narcotic and condiment Papaver somniferum cultivars
    • Frick S, Kramell R, Schmidt J, Fist AJ, Kutchan TM (2005) Comparative qualitative and quantitative determination of alkaloids in narcotic and condiment Papaver somniferum cultivars. J Nat Prod 68: 666-673.
    • (2005) J Nat Prod , vol.68 , pp. 666-673
    • Frick, S.1    Kramell, R.2    Schmidt, J.3    Fist, A.J.4    Kutchan, T.M.5
  • 21
    • 33847279410 scopus 로고    scopus 로고
    • Metabolic engineering of a morphine biosynthetic P450 in opium poppy surpasses breeding
    • Frick S, Kramell R, Kutchan TM (2007) Metabolic engineering of a morphine biosynthetic P450 in opium poppy surpasses breeding. Metab Eng 9: 169-176.
    • (2007) Metab Eng , vol.9 , pp. 169-176
    • Frick, S.1    Kramell, R.2    Kutchan, T.M.3
  • 23
    • 44049113918 scopus 로고
    • Formation of salutaridine from (R)-reticuline by a membrane bound cytochrome P450 enzyme from Papaver somniferum
    • Gerardy R, Zenk MH (1993) Formation of salutaridine from (R)-reticuline by a membrane bound cytochrome P450 enzyme from Papaver somniferum. Phytochemistry 32: 79-86.
    • (1993) Phytochemistry , vol.32 , pp. 79-86
    • Gerardy, R.1    Zenk, M.H.2
  • 24
    • 69949174213 scopus 로고    scopus 로고
    • CYP719B1 is salutaridine synthase, the C-C phenol-coupling enzyme of morphine biosynthesis in opium poppy
    • Gesell A, Rolf M, Ziegler J, Díaz Chávez ML, Huang F-C, Kutchan TM (2009) CYP719B1 is salutaridine synthase, the C-C phenol-coupling enzyme of morphine biosynthesis in opium poppy. J Biol Chem 284: 24432-24442.
    • (2009) J Biol Chem , vol.284 , pp. 24432-24442
    • Gesell, A.1    Rolf, M.2    Ziegler, J.3    Díaz Chávez, M.L.4    Huang, F.-C.5    Kutchan, T.M.6
  • 25
    • 0037023349 scopus 로고    scopus 로고
    • A draft sequence of the rice genome (Oryza sativa ssp japonica)
    • Goff SA, Ricker D, Lan TH et al (2002) A draft sequence of the rice genome (Oryza sativa ssp japonica). Science 296: 92-100.
    • (2002) Science , vol.296 , pp. 92-100
    • Goff, S.A.1    Ricker, D.2    Lan, T.H.3
  • 26
    • 0035903228 scopus 로고    scopus 로고
    • Molecular characterization of the salutaridinol 7-O-acetyltransferase involved in morphine biosynthesis in opium poppy Papaversomniferum
    • Grothe T, Lenz R, Kutchan TM (2001) Molecular characterization of the salutaridinol 7-O-acetyltransferase involved in morphine biosynthesis in opium poppy Papaversomniferum. J Biol Chem 276: 30717-30723.
    • (2001) J Biol Chem , vol.276 , pp. 30717-30723
    • Grothe, T.1    Lenz, R.2    Kutchan, T.M.3
  • 27
    • 77949847651 scopus 로고    scopus 로고
    • Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy
    • Hagel JM, Facchini PJ (2010) Dioxygenases catalyze the O-demethylation steps of morphine biosynthesis in opium poppy. Nature Chem Biol 6: 273-275.
    • (2010) Nature Chem Biol , vol.6 , pp. 273-275
    • Hagel, J.M.1    Facchini, P.J.2
  • 28
    • 53749090789 scopus 로고    scopus 로고
    • 1H nuclear magnetic resonance metabolite profiling as a functional genomics platform to investigate alkaloid biosynthesis in opium poppy
    • 1H nuclear magnetic resonance metabolite profiling as a functional genomics platform to investigate alkaloid biosynthesis in opium poppy. Plant Physiol 147: 1805-1821.
    • (2008) Plant Physiol , vol.147 , pp. 1805-1821
    • Hagel, J.M.1    Weljie, A.M.2    Vogel, H.J.3    Facchini, P.J.4
  • 30
    • 2142751582 scopus 로고    scopus 로고
    • 1,2-Dehydroreticuline synthase, the branch point enzyme opening the morphinan biosynthetic pathway
    • Hirata K, Poeaknapo C, Schmidt J, Zenk MH (2004) 1, 2-Dehydroreticuline synthase, the branch point enzyme opening the morphinan biosynthetic pathway. Phytochemistry 65: 1039-1046.
    • (2004) Phytochemistry , vol.65 , pp. 1039-1046
    • Hirata, K.1    Poeaknapo, C.2    Schmidt, J.3    Zenk, M.H.4
  • 31
    • 0034161828 scopus 로고    scopus 로고
    • Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somniferum
    • Huang FC, Kutchan TM (2000) Distribution of morphinan and benzo[c]phenanthridine alkaloid gene transcript accumulation in Papaver somniferum. Phytochemistry 53: 555-564.
    • (2000) Phytochemistry , vol.53 , pp. 555-564
    • Huang, F.C.1    Kutchan, T.M.2
  • 32
    • 0031882371 scopus 로고    scopus 로고
    • Plant O-methyltransferases: molecular analysis, common signature and classification
    • Ibrahim RK, Bruneau A, Bantignies B (1998) Plant O-methyltransferases: molecular analysis, common signature and classification. Plant Mol Biol 36: 1-10.
    • (1998) Plant Mol Biol , vol.36 , pp. 1-10
    • Ibrahim, R.K.1    Bruneau, A.2    Bantignies, B.3
  • 33
    • 0030512774 scopus 로고    scopus 로고
    • Elicitation of dihydrobenzophenanthridine oxidase in Sanguinaria canadensis cell cultures
    • Ignatov A, Clark WG, Cline SD, Psenak M, Krueger J, Coscia CJ (1996) Elicitation of dihydrobenzophenanthridine oxidase in Sanguinaria canadensis cell cultures. Phytochemistry 43: 1141-1144.
    • (1996) Phytochemistry , vol.43 , pp. 1141-1144
    • Ignatov, A.1    Clark, W.G.2    Cline, S.D.3    Psenak, M.4    Krueger, J.5    Coscia, C.J.6
  • 34
    • 0141755310 scopus 로고    scopus 로고
    • Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family from cultured Coptis japonica cells
    • Ikezawa N, Tanaka M, Nagayoshi M, Shinkyo R, Sakaki T, Inouye K, Sato F (2003) Molecular cloning and characterization of CYP719, a methylenedioxy bridge-forming enzyme that belongs to a novel P450 family from cultured Coptis japonica cells. J Biol Chem 278: 38557-38565.
    • (2003) J Biol Chem , vol.278 , pp. 38557-38565
    • Ikezawa, N.1    Tanaka, M.2    Nagayoshi, M.3    Shinkyo, R.4    Sakaki, T.5    Inouye, K.6    Sato, F.7
  • 35
    • 33846827049 scopus 로고    scopus 로고
    • Molecular cloning and characterization of methylenedioxy bridge-forming enzymes involved in stylopine biosynthesis in Eschscholzia californica
    • Ikezawa N, Iwasa K, Sato F (2007) Molecular cloning and characterization of methylenedioxy bridge-forming enzymes involved in stylopine biosynthesis in Eschscholzia californica. FEBS J 274: 1019-1035.
    • (2007) FEBS J , vol.274 , pp. 1019-1035
    • Ikezawa, N.1    Iwasa, K.2    Sato, F.3
  • 36
    • 58149242229 scopus 로고    scopus 로고
    • CYP719A subfamily of cytochrome P450 oxygenases and isoquinoline alkaloid biosynthesis in Eschscholzia californica
    • Ikezawa N, Iwasa K, Sato F (2009) CYP719A subfamily of cytochrome P450 oxygenases and isoquinoline alkaloid biosynthesis in Eschscholzia californica. Plant Cell Rep 28: 123-133.
    • (2009) Plant Cell Rep , vol.28 , pp. 123-133
    • Ikezawa, N.1    Iwasa, K.2    Sato, F.3
  • 37
    • 70450169667 scopus 로고    scopus 로고
    • De Novo sequencing of plant genomes using second-generation technologies
    • Imelfort M, Edwards D (2009) De Novo sequencing of plant genomes using second-generation technologies. Briefings Bioinfo 10: 609-618.
    • (2009) Briefings Bioinfo , vol.10 , pp. 609-618
    • Imelfort, M.1    Edwards, D.2
  • 39
    • 64949176017 scopus 로고    scopus 로고
    • RNAi suppression of the morphine biosynthetic gene salAT and evidence of association of pathway enzymes
    • Kempe K, Higashi Y, Frick S, Sabarna K, Kutchan TM (2009) RNAi suppression of the morphine biosynthetic gene salAT and evidence of association of pathway enzymes. Phytochemistry 70: 579-589.
    • (2009) Phytochemistry , vol.70 , pp. 579-589
    • Kempe, K.1    Higashi, Y.2    Frick, S.3    Sabarna, K.4    Kutchan, T.M.5
  • 41
    • 78649499936 scopus 로고    scopus 로고
    • Norcoclaurine synthase is a member of the pathogenesis-related 10/Bet v1 protein family
    • Lee EJ, Facchini PJ (2010) Norcoclaurine synthase is a member of the pathogenesis-related 10/Bet v1 protein family. Plant Cell 22: 3489-3503.
    • (2010) Plant Cell , vol.22 , pp. 3489-3503
    • Lee, E.J.1    Facchini, P.J.2
  • 42
    • 80455173600 scopus 로고    scopus 로고
    • Tyrosine aminotransferase contributes to benzylisoquinoline alkaloid biosynthesis in opium poppy
    • 21949209
    • Lee EJ, Facchini PJ (2011) Tyrosine aminotransferase contributes to benzylisoquinoline alkaloid biosynthesis in opium poppy. Plant Physiol PMID: 21949209.
    • (2011) Plant Physiol PMID
    • Lee, E.J.1    Facchini, P.J.2
  • 43
    • 0028245117 scopus 로고
    • Closure of the oxide bridge in morphine biosynthesis
    • Lenz R, Zenk MH (1994) Closure of the oxide bridge in morphine biosynthesis. Tetrahedron Lett 35: 3897-3900.
    • (1994) Tetrahedron Lett , vol.35 , pp. 3897-3900
    • Lenz, R.1    Zenk, M.H.2
  • 44
    • 34447529465 scopus 로고    scopus 로고
    • Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy
    • Liscombe DK, Facchini PJ (2007) Molecular cloning and characterization of tetrahydroprotoberberine cis-N-methyltransferase, an enzyme involved in alkaloid biosynthesis in opium poppy. J Biol Chem 282: 14741-14751.
    • (2007) J Biol Chem , vol.282 , pp. 14741-14751
    • Liscombe, D.K.1    Facchini, P.J.2
  • 45
    • 20444396193 scopus 로고    scopus 로고
    • Evidence for the monophyletic evolution of benzylisoquinoline alkaloid biosynthesis in angiosperms
    • Liscombe DK, MacLeod BP, Loukanina N, Nandi OI, Facchini PJ (2005) Evidence for the monophyletic evolution of benzylisoquinoline alkaloid biosynthesis in angiosperms. Phytochemistry 66: 2501-2520.
    • (2005) Phytochemistry , vol.66 , pp. 2501-2520
    • Liscombe, D.K.1    Macleod, B.P.2    Loukanina, N.3    Nandi, O.I.4    Facchini, P.J.5
  • 46
    • 72449148338 scopus 로고    scopus 로고
    • Targeted metabolite and transcript profiling for elucidating enzyme function: isolation of novel N-methyltransferases from three benzylisoquinoline alkaloid-producing species
    • Liscombe DK, Ziegler J, Schmidt J, Ammer C, Facchini PJ (2009) Targeted metabolite and transcript profiling for elucidating enzyme function: isolation of novel N-methyltransferases from three benzylisoquinoline alkaloid-producing species. Plant J 60: 729-743.
    • (2009) Plant J , vol.60 , pp. 729-743
    • Liscombe, D.K.1    Ziegler, J.2    Schmidt, J.3    Ammer, C.4    Facchini, P.J.5
  • 47
    • 77956659870 scopus 로고    scopus 로고
    • Comparison of 454-ESTs from Huperzia serrata and Phlegmariurus carinatus reveals putative genes involved in lycopodium alkaloid biosynthesis and developmental regulation
    • Luo H, Li Y, Sun C, Wu Q, Song J, Sun Y, Steinmetz A, Chen S (2010) Comparison of 454-ESTs from Huperzia serrata and Phlegmariurus carinatus reveals putative genes involved in lycopodium alkaloid biosynthesis and developmental regulation. BMC Plant Biol 10: 209-224.
    • (2010) BMC Plant Biol , vol.10 , pp. 209-224
    • Luo, H.1    Li, Y.2    Sun, C.3    Wu, Q.4    Song, J.5    Sun, Y.6    Steinmetz, A.7    Chen, S.8
  • 50
    • 79951571893 scopus 로고    scopus 로고
    • Unusual P450 reactions in plant secondary metabolism
    • Mizutani M, Sato F (2011) Unusual P450 reactions in plant secondary metabolism. Arch Biochem Biophys 507: 194-203.
    • (2011) Arch Biochem Biophys , vol.507 , pp. 194-203
    • Mizutani, M.1    Sato, F.2
  • 52
    • 0034725710 scopus 로고    scopus 로고
    • Molecular characterization of the S-adenosyl-l-methionine: 3′-hydroxy-N-methylcoclaurine 4′-O-methyltransferase involved in isoquinoline alkaloid biosynthesis in Coptis japonica
    • Morishige T, Tsujita T, Yamada Y, Sato F (2000) Molecular characterization of the S-adenosyl-l-methionine: 3′-hydroxy-N-methylcoclaurine 4′-O-methyltransferase involved in isoquinoline alkaloid biosynthesis in Coptis japonica. J Biol Chem 275: 23398-23405.
    • (2000) J Biol Chem , vol.275 , pp. 23398-23405
    • Morishige, T.1    Tsujita, T.2    Yamada, Y.3    Sato, F.4
  • 53
    • 0036439059 scopus 로고    scopus 로고
    • Molecular cloning of columbamine O-methyltransferase from cultured Coptisjaponica of cells
    • Morishige T, Dubouzet E, Choi KB, Yazaki K, Sato F (2002) Molecular cloning of columbamine O-methyltransferase from cultured Coptisjaponica of cells. Eur J Biochem 269: 5659-5667.
    • (2002) Eur J Biochem , vol.269 , pp. 5659-5667
    • Morishige, T.1    Dubouzet, E.2    Choi, K.B.3    Yazaki, K.4    Sato, F.5
  • 54
    • 4544346814 scopus 로고    scopus 로고
    • In vivo bioconversion of tetrahydroisoquinoline by recombinant coclaurine N-methyltransferase
    • Morishige T, Choi KB, Sato F (2004) In vivo bioconversion of tetrahydroisoquinoline by recombinant coclaurine N-methyltransferase. Biosci Biotechnol Biochem 68: 939-941.
    • (2004) Biosci Biotechnol Biochem , vol.68 , pp. 939-941
    • Morishige, T.1    Choi, K.B.2    Sato, F.3
  • 55
    • 78650173423 scopus 로고    scopus 로고
    • Computational mass spectrometry for metabolomics: identification of metabolites and small molecules
    • Neuman S, Bocker S (2010) Computational mass spectrometry for metabolomics: identification of metabolites and small molecules. Anal Bioanal Chem 398: 2779-2788.
    • (2010) Anal Bioanal Chem , vol.398 , pp. 2779-2788
    • Neuman, S.1    Bocker, S.2
  • 56
    • 0018131820 scopus 로고
    • Selection for high thebaine/low morphine content (cpv Morph: The) in Papaver somniferum L
    • Nyman U (1978) Selection for high thebaine/low morphine content (cpv Morph: The) in Papaver somniferum L. Heriditas 89: 43-50.
    • (1978) Heriditas , vol.89 , pp. 43-50
    • Nyman, U.1
  • 57
    • 0019131040 scopus 로고
    • Selection for high thebaine/low morphine content in Papaver somniferum L. II. Studies of the I4 and I5 generations from spontaneous mutant
    • Nyman U (1980) Selection for high thebaine/low morphine content in Papaver somniferum L. II. Studies of the I4 and I5 generations from spontaneous mutant. Heriditas 93: 121-124.
    • (1980) Heriditas , vol.93 , pp. 121-124
    • Nyman, U.1
  • 58
    • 0347317979 scopus 로고    scopus 로고
    • (R,S)-Reticuline 7-O-methyltransferase and (R,S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum- cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy
    • Ounaroon A, Decker G, Schmidt J, Lottspeich F, Kutchan TM (2003) (R, S)-Reticuline 7-O-methyltransferase and (R, S)-norcoclaurine 6-O-methyltransferase of Papaver somniferum- cDNA cloning and characterization of methyl transfer enzymes of alkaloid biosynthesis in opium poppy. Plant J 36: 808-819.
    • (2003) Plant J , vol.36 , pp. 808-819
    • Ounaroon, A.1    Decker, G.2    Schmidt, J.3    Lottspeich, F.4    Kutchan, T.M.5
  • 59
    • 0346494835 scopus 로고    scopus 로고
    • The TIGR Plant Repeat Databases: a collective resource for identification of repetitive sequences in plants. NAR 32
    • Ouyang S, Buell CR (2004) The TIGR Plant Repeat Databases: a collective resource for identification of repetitive sequences in plants. NAR 32. Database Issue 2004: D360-D363.
    • (2004) Database Issue , vol.2004
    • Ouyang, S.1    Buell, C.R.2
  • 62
    • 0032033414 scopus 로고    scopus 로고
    • Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3′-hydroxylase (CYP80b1), a new methyl jasmonate-inducible cytochrome P-450-dependent monooxygenase of benzylisoquinoline alkaloid biosynthesis
    • Pauli HH, Kutchan TM (1998) Molecular cloning and functional heterologous expression of two alleles encoding (S)-N-methylcoclaurine 3′-hydroxylase (CYP80b1), a new methyl jasmonate-inducible cytochrome P-450-dependent monooxygenase of benzylisoquinoline alkaloid biosynthesis. Plant J 13: 793-801.
    • (1998) Plant J , vol.13 , pp. 793-801
    • Pauli, H.H.1    Kutchan, T.M.2
  • 63
    • 70349499351 scopus 로고    scopus 로고
    • Functional characterization of a novel benzylisoquinoline-O-methyltransferase suggests its involvement in papaverine biosynthesis in opium poppy (Papaver somniferum L)
    • Pienkny S, Brandt W, Schmidt J, Kramell R, Ziegler J (2009) Functional characterization of a novel benzylisoquinoline-O-methyltransferase suggests its involvement in papaverine biosynthesis in opium poppy (Papaver somniferum L). Plant J 60: 56-67.
    • (2009) Plant J , vol.60 , pp. 56-67
    • Pienkny, S.1    Brandt, W.2    Schmidt, J.3    Kramell, R.4    Ziegler, J.5
  • 66
    • 0000369164 scopus 로고
    • Enzymatic formation of protopines by a microsomal cytochrome P-450 system of Corydalis vaginans
    • Rueffer M, Zenk MH (1987) Enzymatic formation of protopines by a microsomal cytochrome P-450 system of Corydalis vaginans. Tetrahedron Lett 28: 5307-5310.
    • (1987) Tetrahedron Lett , vol.28 , pp. 5307-5310
    • Rueffer, M.1    Zenk, M.H.2
  • 67
    • 0000801516 scopus 로고
    • S-adenosyl-l-methionine: columbamine-O-methyltransferase, a compartmentalized enzyme in protoberberine biosynthesis
    • Rueffer M, Amann M, Zenk MH (1986) S-adenosyl-l-methionine: columbamine-O-methyltransferase, a compartmentalized enzyme in protoberberine biosynthesis. Plant Cell Rep 3: 182-185.
    • (1986) Plant Cell Rep , vol.3 , pp. 182-185
    • Rueffer, M.1    Amann, M.2    Zenk, M.H.3
  • 68
    • 0037072805 scopus 로고    scopus 로고
    • Purification and characterization of norcoclaurine synthase, the first committed enzyme in benzylisoquinoline alkaloid biosynthesis in plants
    • Samanani N, Facchini PJ (2002) Purification and characterization of norcoclaurine synthase, the first committed enzyme in benzylisoquinoline alkaloid biosynthesis in plants. J Biol Chem 277: 33878-33883.
    • (2002) J Biol Chem , vol.277 , pp. 33878-33883
    • Samanani, N.1    Facchini, P.J.2
  • 69
    • 6444243887 scopus 로고    scopus 로고
    • Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis
    • Samanani N, Liscombe DK, Facchini PJ (2004) Molecular cloning and characterization of norcoclaurine synthase, an enzyme catalyzing the first committed step in benzylisoquinoline alkaloid biosynthesis. Plant J 40: 302-313.
    • (2004) Plant J , vol.40 , pp. 302-313
    • Samanani, N.1    Liscombe, D.K.2    Facchini, P.J.3
  • 70
    • 20444379109 scopus 로고    scopus 로고
    • Cell type-specific localization of transcripts encoding nine consecutive enzymes involved in protoberberine alkaloid biosynthesis
    • Samanani N, Park SU, Facchini PJ (2005) Cell type-specific localization of transcripts encoding nine consecutive enzymes involved in protoberberine alkaloid biosynthesis. Plant Cell 17: 915-926.
    • (2005) Plant Cell , vol.17 , pp. 915-926
    • Samanani, N.1    Park, S.U.2    Facchini, P.J.3
  • 71
    • 33746489315 scopus 로고    scopus 로고
    • The role of phloem sieve elements and laticifers in the biosynthesis and accumulation of alkaloids in opium poppy
    • Samanani N, Alcantara J, Bourgault R, Zulak KG, Facchini PJ (2006) The role of phloem sieve elements and laticifers in the biosynthesis and accumulation of alkaloids in opium poppy. Plant J 47: 547-563.
    • (2006) Plant J , vol.47 , pp. 547-563
    • Samanani, N.1    Alcantara, J.2    Bourgault, R.3    Zulak, K.G.4    Facchini, P.J.5
  • 73
    • 24344445346 scopus 로고    scopus 로고
    • Analysis of benzylisoquinoline-type alkaloids by electrospray tandem mass spectrometry and atmospheric pressure photoionization
    • Schmidt J, Raith K, Boettcher C, Zenk MH (2005) Analysis of benzylisoquinoline-type alkaloids by electrospray tandem mass spectrometry and atmospheric pressure photoionization. Eur J Mass Spectrom 11: 325-333.
    • (2005) Eur J Mass Spectrom , vol.11 , pp. 325-333
    • Schmidt, J.1    Raith, K.2    Boettcher, C.3    Zenk, M.H.4
  • 75
    • 0001828472 scopus 로고
    • Partial purification and characterization of dihydrobenzophenanthridine oxidase from Eschscholtzia californica cell suspension cultures
    • Schumacher H-M, Zenk MH (1988) Partial purification and characterization of dihydrobenzophenanthridine oxidase from Eschscholtzia californica cell suspension cultures. Plant Cell Rep 7: 43-46.
    • (1988) Plant Cell Rep , vol.7 , pp. 43-46
    • Schumacher, H.-M.1    Zenk, M.H.2
  • 77
    • 33646810509 scopus 로고    scopus 로고
    • Honeybees foraging response in genetically diversified opium poppy
    • Srivastava HK, Singh D (2006) Honeybees foraging response in genetically diversified opium poppy. Bioresour Technol 97: 1578-1581.
    • (2006) Bioresour Technol , vol.97 , pp. 1578-1581
    • Srivastava, H.K.1    Singh, D.2
  • 78
    • 77951121533 scopus 로고    scopus 로고
    • De novo sequencing and analysis of the American ginseng root transcriptome using GS GLX Titanium platform to discover putative genes involved in ginsenoside biosynthesis
    • Sun C, Li Y, Wu Q, Luo H, Sun Y, Song J, Lui EMK, Chen S (2010) De novo sequencing and analysis of the American ginseng root transcriptome using GS GLX Titanium platform to discover putative genes involved in ginsenoside biosynthesis. BMC Genomics 11: 262-273.
    • (2010) BMC Genomics , vol.11 , pp. 262-273
    • Sun, C.1    Li, Y.2    Wu, Q.3    Luo, H.4    Sun, Y.5    Song, J.6    Lui, E.M.K.7    Chen, S.8
  • 79
    • 79956066785 scopus 로고    scopus 로고
    • Comparison of sequence reads obtained from three next-generation sequencing platforms
    • Suzuki S, Ono N, Furusawa C, Ying BW, Yomo T (2011) Comparison of sequence reads obtained from three next-generation sequencing platforms. PLoS 6: e19534: 1-6.
    • (2011) PLoS 6: E19534 , pp. 1-6
    • Suzuki, S.1    Ono, N.2    Furusawa, C.3    Ying, B.W.4    Yomo, T.5
  • 81
    • 0029137429 scopus 로고
    • Molecular cloning and characterization of S-adenosyl-l-methionine: scoulerine-9-O-methyltransferase from cultured cells of Coptis japonica
    • Takeshita N, Fujiwara H, Mimura H, Fitchen JH, Yamada Y, Sato F (1995) Molecular cloning and characterization of S-adenosyl-l-methionine: scoulerine-9-O-methyltransferase from cultured cells of Coptis japonica. Plant Cell Physiol 36: 29-36.
    • (1995) Plant Cell Physiol , vol.36 , pp. 29-36
    • Takeshita, N.1    Fujiwara, H.2    Mimura, H.3    Fitchen, J.H.4    Yamada, Y.5    Sato, F.6
  • 82
    • 0000860639 scopus 로고
    • Elicitor induction and characterization of microsomal protopine-6-hydroxylase, the central enzyme in benzophenanthridine alkaloid biosynthesis
    • Tanahashi T, Zenk MH (1990) Elicitor induction and characterization of microsomal protopine-6-hydroxylase, the central enzyme in benzophenanthridine alkaloid biosynthesis. Phytochemistry 29: 1113-1122.
    • (1990) Phytochemistry , vol.29 , pp. 1113-1122
    • Tanahashi, T.1    Zenk, M.H.2
  • 83
  • 84
    • 0033152629 scopus 로고    scopus 로고
    • Molecular cloning and functional expression of codeinone reductase: the penultimate enzyme in morphine biosynthesis in the opium poppy Papaver somniferum
    • Unterlinner B, Lenz R, Kutchan TM (1999) Molecular cloning and functional expression of codeinone reductase: the penultimate enzyme in morphine biosynthesis in the opium poppy Papaver somniferum. Plant J 18: 465-475.
    • (1999) Plant J , vol.18 , pp. 465-475
    • Unterlinner, B.1    Lenz, R.2    Kutchan, T.M.3
  • 86
    • 70449516453 scopus 로고    scopus 로고
    • Global characterization of Artemisia annua glandular trichome using 454 pyrosequencing
    • Wang W, Wang Y, Zhang Q, Qi Y, Guo D (2009) Global characterization of Artemisia annua glandular trichome using 454 pyrosequencing. BMC Genomics 10: 465-475.
    • (2009) BMC Genomics , vol.10 , pp. 465-475
    • Wang, W.1    Wang, Y.2    Zhang, Q.3    Qi, Y.4    Guo, D.5
  • 87
    • 34250666153 scopus 로고    scopus 로고
    • Sampling the Arabidopsis transcriptome with massively parallel pyrosequencing
    • Weber AP, Weber KL, Carr K, Wilkerson C, Ohlrogge JB (2007) Sampling the Arabidopsis transcriptome with massively parallel pyrosequencing. Plant Physiol 144: 32-42.
    • (2007) Plant Physiol , vol.144 , pp. 32-42
    • Weber, A.P.1    Weber, K.L.2    Carr, K.3    Wilkerson, C.4    Ohlrogge, J.B.5
  • 88
    • 4644289320 scopus 로고    scopus 로고
    • The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaversomniferum
    • Weid M, Ziegler J, Kutchan TM (2004) The roles of latex and the vascular bundle in morphine biosynthesis in the opium poppy, Papaversomniferum. Proc Natl Acad Sci USA 101: 13957-13962.
    • (2004) Proc Natl Acad Sci USA , vol.101 , pp. 13957-13962
    • Weid, M.1    Ziegler, J.2    Kutchan, T.M.3
  • 89
    • 3242655621 scopus 로고    scopus 로고
    • Metabolic channeling in plants
    • Winkel BSJ (2004) Metabolic channeling in plants. Annu Rev Plant Biol 55: 85-107.
    • (2004) Annu Rev Plant Biol , vol.55 , pp. 85-107
    • Winkel, B.S.J.1
  • 90
    • 69149089956 scopus 로고    scopus 로고
    • Effectiveness of chemical protection against weeds applied to poppy (Papaver somniferum L.)
    • Wojtowicz M, Wojtowicz A (2009) Effectiveness of chemical protection against weeds applied to poppy (Papaver somniferum L.). J Plant Prot Res 49: 209-215.
    • (2009) J Plant Prot Res , vol.49 , pp. 209-215
    • Wojtowicz, M.1    Wojtowicz, A.2
  • 92
    • 0037023384 scopus 로고    scopus 로고
    • A draft sequence of the rice genome (Oryza sativa ssp indica)
    • Yu J, Hu SN, Wang J et al (2002) A draft sequence of the rice genome (Oryza sativa ssp indica). Science 296: 79-92.
    • (2002) Science , vol.296 , pp. 79-92
    • Yu, J.1    Hu, S.N.2    Wang, J.3
  • 93
    • 77649112643 scopus 로고    scopus 로고
    • Development of a EST dataset and characterization of EST-SSRs in a traditional Chinese medicinal plant, Epimedium sagittatum (Sieb. Et Zucc.) Maxim
    • Zeng S, Xiao G, Guo J, Fei Z, Xu Y, Roe BA, Wang Y (2010) Development of a EST dataset and characterization of EST-SSRs in a traditional Chinese medicinal plant, Epimedium sagittatum (Sieb. Et Zucc.) Maxim. BMC Genomics 11: 94.
    • (2010) BMC Genomics , vol.11 , pp. 94
    • Zeng, S.1    Xiao, G.2    Guo, J.3    Fei, Z.4    Xu, Y.5    Roe, B.A.6    Wang, Y.7
  • 95
    • 26644468125 scopus 로고    scopus 로고
    • Comparative macroarray analysis of morphine containing Papaver somniferum and eight morphine free Papaver species identifies an O-methyltransferase involved in benzylisoquinoline biosynthesis
    • Ziegler J, Díaz-Chávez ML, Kramell R, Ammer C, Kutchan TM (2005) Comparative macroarray analysis of morphine containing Papaver somniferum and eight morphine free Papaver species identifies an O-methyltransferase involved in benzylisoquinoline biosynthesis. Planta 222: 458-471.
    • (2005) Planta , vol.222 , pp. 458-471
    • Ziegler, J.1    Díaz-Chávez, M.L.2    Kramell, R.3    Ammer, C.4    Kutchan, T.M.5
  • 96
    • 33749241876 scopus 로고    scopus 로고
    • Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis
    • Ziegler J, Voigtlander S, Schmidt J, Kramell R, Miersch O, Ammer C, Gesell A, Kutchan TM (2006) Comparative transcript and alkaloid profiling in Papaver species identifies a short chain dehydrogenase/reductase involved in morphine biosynthesis. Plant J 48: 177-192.
    • (2006) Plant J , vol.48 , pp. 177-192
    • Ziegler, J.1    Voigtlander, S.2    Schmidt, J.3    Kramell, R.4    Miersch, O.5    Ammer, C.6    Gesell, A.7    Kutchan, T.M.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.