Operative strategy modifies risk of pouch-related outcomes in patients with ulcerative colitis on preoperative anti-tumor necrosis factor-α therapy

Diseases of the Colon and Rectum

Volumn 56, Issue 11, 2013, Pages 1243-1252

  Gu, Jinyu ^a   Remzi, Feza H ^a   Shen, Bo ^a   Vogel, Jon D ^a   Kiran, Ravi P ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

Anti tumor necrosis factor agents; Ileal pouch anal anastomosis; Infliximab; Subtotal colectomy; Ulcerative colitis

Indexed keywords

ADALIMUMAB; AZATHIOPRINE; CERTOLIZUMAB PEGOL; MERCAPTOPURINE; STEROID; TUMOR NECROSIS FACTOR ALPHA ANTIBODY;

ADULT; ANASTOMOSIS LEAKAGE; ARTICLE; BLOOD CELL COUNT; COLON RESECTION; COMORBIDITY; COMPARATIVE STUDY; CONTROLLED STUDY; DISEASE SEVERITY; FEMALE; FOLLOW UP; HUMAN; ILEOSTOMY; ILEUM POUCH; LEUKOCYTOSIS; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PELVIS; PREOPERATIVE CARE; PROCTOCOLECTOMY; QUALITY OF LIFE; RECTUM RESECTION; RISK MANAGEMENT; SEPSIS; STEROID THERAPY; SURGICAL APPROACH; SURGICAL PATIENT; SURGICAL TECHNIQUE; ULCERATIVE COLITIS; WOUND INFECTION;

ADOLESCENT; ADULT; AGED; ANTIBODIES, MONOCLONAL; ANTIBODIES, MONOCLONAL, HUMANIZED; COLITIS, ULCERATIVE; FEMALE; GASTROINTESTINAL AGENTS; HUMANS; ILEOSTOMY; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; PROCTOCOLECTOMY, RESTORATIVE; PROPORTIONAL HAZARDS MODELS; RETROSPECTIVE STUDIES; RISK FACTORS; SEPSIS; TUMOR NECROSIS FACTOR-ALPHA; YOUNG ADULT;

EID: 84888356081     PISSN: 00123706     EISSN: 15300358     Source Type: Journal    
DOI: 10.1097/DCR.0b013e3182a0e702     Document Type: Article

References (30)

1. Rutgeerts P, Sandborn WJ, Feagan BG, et al. Infliximab for induction and maintenance therapy for ulcerative colitis. N Engl J Med. 2005;353: 2462-2476.
2. Selvasekar CR, Cima RR, Larson DW, et al. Effect of infliximab on short-term complications in patients undergoing operation for chronic ulcerative colitis. J Am Coll Surg. 2007;204: 956-962.
3. Schluender SJ, Ippoliti A, Dubinsky M, et al. Does infliximab influence surgical morbidity of ileal pouch-anal anastomosis in patients with ulcerative colitis? Dis Colon Rectum. 2007;50: 1747-1753.
4. Mor IJ, Vogel JD, da Luz Moreira A, Shen B, Hammel J, Remzi FH. Infliximab in ulcerative colitis is associated with an increased risk of postoperative complications after restorative proctocolectomy. Dis Colon Rectum. 2008;51: 1202-1207.
5. Ferrante M, D'Hoore A, Vermeire S, et al. Corticosteroids but not infliximab increase short-term postoperative infectious complications in patients with ulcerative colitis. Inflamm Bowel Dis. 2009;15: 1062-1070.
6. Coquet-Reinier B, Berdah SV, Grimaud JC, et al. Preoperative infliximab treatment and postoperative complications after laparoscopic restorative proctocolectomy with ileal pouch-anal anastomosis: a case-matched study. Surg Endosc. 2010;24: 1866-1871.
7. Gainsbury ML, Chu DI, Howard LA, et al. Preoperative infliximab is not associated with an increased risk of short-term postoperative complications after restorative proctocolectomy and ileal pouch-anal anastomosis. J Gastrointest Surg. 2011;15: 397-403.
8. Bregnbak D, Mortensen C, Bendtsen F. Infliximab and complications after colectomy in patients with ulcerative colitis. J Crohns Colitis. 2012;6: 281-286.
9. Nørgård BM, Nielsen J, Qvist N, Gradel KO, de Muckadell OB, Kjeldsen J. Pre-operative use of anti-TNF-α agents and the risk of post-operative complications in patients with ulcerative colitis - a nationwide cohort study. Aliment Pharmacol Ther. 2012;35: 1301-1309.
10. Eshuis EJ, Al Saady RL, Stokkers PC, Ponsioen CY, Tanis PJ, Bemelman WA. Previous infliximab therapy and postoperative complications after proctocolectomy with ileum pouch anal anastomosis. J Crohns Colitis. 2013;7: 142-149.
11. Yang Z, Wu Q, Wang F, Wu K, Fan D. Meta-analysis: effect of preoperative infliximab use on early postoperative complications in patients with ulcerative colitis undergoing abdominal surgery. Aliment Pharmacol Ther. 2012;36: 922-928.
12. Kiely JM, Fazio VW, Remzi FH, Shen B, Kiran RP. Pelvic sepsis after IPAA adversely affects function of the pouch and quality of life. Dis Colon Rectum. 2012;55: 387-392.
13. Cohen JL, Strong SA, Hyman NH, et al Standards Practice Task Force American Society of Colon and Rectal Surgeons. Practice parameters for the surgical treatment of ulcerative colitis. Dis Colon Rectum. 2005;48: 1997-2009.
14. Nisar PJ, Kiran RP, Shen B, Remzi FH, Fazio VW. Factors associated with ileoanal pouch failure in patients developing early or late pouch-related fistula. Dis Colon Rectum. 2011;54: 446-453.
15. Shen B, Remzi FH, Lavery IC, Lashner BA, Fazio VW. A proposed classification of ileal pouch disorders and associated complications after restorative proctocolectomy. Clin Gastroenterol Hepatol. 2008;6: 145-158.
16. Gu J, Stocchi L, Geisler DP, Kiran RP. Staged restorative proctocolectomy: laparoscopic or open completion proctectomy after laparoscopic subtotal colectomy? Surg Endosc. 2011;25: 3294-3299.
17. Kunitake H, Hodin R, Shellito PC, Sands BE, Korzenik J, Bordeianou L. Perioperative treatment with infliximab in patients with Crohn's disease and ulcerative colitis is not associated with an increased rate of postoperative complications. J Gastrointest Surg. 2008;12:1730-6 1736.
18. Rizzo G, Armuzzi A, Pugliese D, et al. Anti-TNF-alpha therapies do not increase early postoperative complications in patients with inflammatory bowel disease. An Italian single-center experience. Int J Colorectal Dis. 2011;26: 1435-1444.
19. TRUELO VE SC, WITTS LJ. Cortisone in ulcerative colitis; final report on a therapeutic trial. Br Med J. 1955;2: 1041-1048.
20. Kiran RP, Delaney CP, Senagore AJ, Steel M, Garafalo T, Fazio VW. Outcomes and prediction of hospital readmission after intestinal surgery. J Am Coll Surg. 2004;198: 877-883.
21. Kiran RP, da Luz Moreira A, Remzi FH, et al. Factors associated with septic complications after restorative proctocolectomy. Ann Surg. 2010;251: 436-440.
22. Kronberg U, Kiran RP, Soliman MS, et al. A characterization of factors determining postoperative ileus after laparoscopic colectomy enables the generation of a novel predictive score. Ann Surg. 2011;253: 78-81.
23. Kirat HT, Kiran RP, Lian L, Remzi FH, Fazio VW. Influence of stapler size used at ileal pouch-anal anastomosis on anastomotic leak, stricture, long-term functional outcomes, and quality of life. Am J Surg. 2010;200: 68-72.
24. Stocchi L. Laparoscopic surgery for ulcerative colitis. Clin Colon Rectal Surg. 2010;23: 248-258.
25. El-Gazzaz GS, Kiran RP, Remzi FH, Hull TL, Geisler DP. Outcomes for case-matched laparoscopically assisted versus open restorative proctocolectomy. Br J Surg. 2009;96: 522-526.
26. Colombel JF, Loftus EV Jr, Tremaine WJ, et al. Early postoperative complications are not increased in patients with Crohn's disease treated perioperatively with infliximab or immunosuppressive therapy. Am J Gastroenterol. 2004;99: 878-883.
27. Appau KA, Fazio VW, Shen B, et al. Use of infliximab within 3 months of ileocolonic resection is associated with adverse postoperative outcomes in Crohn's patients. J Gastrointest Surg. 2008;12: 1738-1744.
28. Waterman M, Xu W, Dinani A, et al. Preoperative biological therapy and short-term outcomes of abdominal surgery in patients with inflammatory bowel disease. Gut. 2013;62: 387-394.
29. Kornbluth A, Sachar DB; Practice Parameters Committee of the American College of Gastroenterology. Ulcerative colitis practice guidelines in adults: American College Of Gastroenterology, Practice Parameters Committee. Am J Gastroenterol. 2010;105: 501-524.
30. Vittinghoff E, McCulloch CE. Relaxing the rule of ten events per variable in logistic and Cox regression. Am J Epidemiol. 2007;165: 710-718.