Imaging of superoxide generation in the dopaminergic area of the brain in Parkinson's disease, using mito-TEMPO

ACS Chemical Neuroscience

Volumn 4, Issue 11, 2013, Pages 1439-1445

  Zhelev, Zhivko ^a,b,c   Bakalova, Rumiana ^a,d   Aoki, Ichio ^a   Lazarova, Dessislava ^d   Saga, Tsuneo ^a  

^a NATIONAL INSTITUTE OF RADIOLOGICAL SCIENCES   (Japan)

^b TRAKIA UNIVERSITY   (Bulgaria)

^c INSTITUTE OF BIOPHYSICS AND BIOMEDICAL ENGINEERING   (Bulgaria)

^d UNIVERSITY OF SOFIA   (Bulgaria)

Author keywords

methoxy TEMPO; Mito TEMPO; nitroxide enhanced magnetic resonance imaging; Parkinson's disease; superoxide; TEMPOL

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; MITO TEMPO; NITROXIDE DERIVATIVE; SUPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; BRAIN REGION; BRAIN TISSUE; CONTROLLED STUDY; DEGENERATIVE DISEASE; DOPAMINERGIC SYSTEM; HISTOGRAM; MALE; MOLECULAR IMAGING; MOUSE; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; ANIMALS; ANTIOXIDANTS; CYCLIC N-OXIDES; DISEASE MODELS, ANIMAL; DOPAMINE AGENTS; ELECTRON SPIN RESONANCE SPECTROSCOPY; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; INJECTIONS, INTRAPERITONEAL; MAGNETIC RESONANCE IMAGING; MALE; MICE; MICE, INBRED C57BL; MITOCHONDRIA; NEUROTOXINS; OXIDATION-REDUCTION; PARKINSON DISEASE; REACTIVE OXYGEN SPECIES; SPIN LABELS; SUBSTANTIA NIGRA; SUPEROXIDES;

EID: 84888325471     PISSN: None     EISSN: 19487193     Source Type: Journal    
DOI: 10.1021/cn400159h     Document Type: Article

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