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Volumn 87, Issue 5, 2013, Pages 992-999

Preoperative chemoradiation therapy with capecitabine/oxaliplatin and cetuximab in rectal cancer: Long-term results of a prospective phase 1/2 study

Author keywords

[No Author keywords available]

Indexed keywords

CHEMORADIATION THERAPIES; COMPLETE RESPONSE; DISEASE-FREE SURVIVAL; HISTOPATHOLOGICAL EXAMINATIONS; LONG-TERM RESULTS; METHODS AND MATERIALS; PREDICTIVE FACTORS; PREOPERATIVE CHEMORADIATION;

EID: 84888295577     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2013.09.011     Document Type: Article
Times cited : (17)

References (28)
  • 1
    • 34250345258 scopus 로고    scopus 로고
    • EGFR-targeted anti-cancer drugs in radiotherapy: Preclinical evaluation of mechanisms
    • M. Baumann, M. Krause, and E. Dikomey EGFR-targeted anti-cancer drugs in radiotherapy: preclinical evaluation of mechanisms Radiother Oncol 83 2007 238 248
    • (2007) Radiother Oncol , vol.83 , pp. 238-248
    • Baumann, M.1    Krause, M.2    Dikomey, E.3
  • 2
    • 26844465462 scopus 로고    scopus 로고
    • Prognostic impact of epidermal growth factor receptor (EGFR) expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer
    • D. Azria, F. Bibeau, and N. Barbier Prognostic impact of epidermal growth factor receptor (EGFR) expression on loco-regional recurrence after preoperative radiotherapy in rectal cancer BMC Cancer 5 2005 62
    • (2005) BMC Cancer , vol.5 , pp. 62
    • Azria, D.1    Bibeau, F.2    Barbier, N.3
  • 3
    • 58149345226 scopus 로고    scopus 로고
    • Neoadjuvant treatment with single-agent cetuximab followed by 5-FU, cetuximab, and pelvic radiotherapy: A phase II study in locally advanced rectal cancer
    • F. Bertolini, S. Chiara, and C. Bengala Neoadjuvant treatment with single-agent cetuximab followed by 5-FU, cetuximab, and pelvic radiotherapy: a phase II study in locally advanced rectal cancer Int J Radiat Oncol Biol Phys 73 2009 466 472
    • (2009) Int J Radiat Oncol Biol Phys , vol.73 , pp. 466-472
    • Bertolini, F.1    Chiara, S.2    Bengala, C.3
  • 4
    • 67149086939 scopus 로고    scopus 로고
    • Molecular targeted treatment and radiation therapy for rectal cancer
    • F. Marquardt, F. Rodel, and G. Capalbo Molecular targeted treatment and radiation therapy for rectal cancer Strahlenther Onkol 185 2009 371 378
    • (2009) Strahlenther Onkol , vol.185 , pp. 371-378
    • Marquardt, F.1    Rodel, F.2    Capalbo, G.3
  • 5
    • 34047179551 scopus 로고    scopus 로고
    • Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer
    • J.P. Machiels, C. Sempoux, and P. Scalliet Phase I/II study of preoperative cetuximab, capecitabine, and external beam radiotherapy in patients with rectal cancer Ann Oncol 18 2007 738 744
    • (2007) Ann Oncol , vol.18 , pp. 738-744
    • Machiels, J.P.1    Sempoux, C.2    Scalliet, P.3
  • 6
    • 39749153032 scopus 로고    scopus 로고
    • Phase I-II trial of cetuximab, capecitabine, oxaliplatin, and radiotherapy as preoperative treatment in rectal cancer
    • C. Rodel, D. Arnold, and M. Hipp Phase I-II trial of cetuximab, capecitabine, oxaliplatin, and radiotherapy as preoperative treatment in rectal cancer Int J Radiat Oncol Biol Phys 70 2008 1081 1086
    • (2008) Int J Radiat Oncol Biol Phys , vol.70 , pp. 1081-1086
    • Rodel, C.1    Arnold, D.2    Hipp, M.3
  • 7
    • 67749097665 scopus 로고    scopus 로고
    • Cetuximab in combination with capecitabine, irinotecan, and radiotherapy for patients with locally advanced rectal cancer: Results of a phase II MARGIT trial
    • K. Horisberger, A. Treschl, and S. Mai Cetuximab in combination with capecitabine, irinotecan, and radiotherapy for patients with locally advanced rectal cancer: results of a phase II MARGIT trial Int J Radiat Oncol Biol Phys 74 2009 1487 1493
    • (2009) Int J Radiat Oncol Biol Phys , vol.74 , pp. 1487-1493
    • Horisberger, K.1    Treschl, A.2    Mai, S.3
  • 8
    • 84755160772 scopus 로고    scopus 로고
    • Preoperative radiotherapy of advanced rectal cancer with capecitabine and oxaliplatin with or without cetuximab: A pooled analysis of three prospective phase I-II trials
    • C. Weiss, D. Arnold, and K. Dellas Preoperative radiotherapy of advanced rectal cancer with capecitabine and oxaliplatin with or without cetuximab: A pooled analysis of three prospective phase I-II trials Int J Radiat Oncol Biol Phys 78 2010 472 478
    • (2010) Int J Radiat Oncol Biol Phys , vol.78 , pp. 472-478
    • Weiss, C.1    Arnold, D.2    Dellas, K.3
  • 9
    • 84867031601 scopus 로고    scopus 로고
    • Effect of neoadjuvant cetuximab, capecitabine, and radiotherapy for locally advanced rectal cancer: Results of a phase II study
    • P.L. Sun, B. Li, and Q.F. Ye Effect of neoadjuvant cetuximab, capecitabine, and radiotherapy for locally advanced rectal cancer: results of a phase II study Int J Colorectal Dis 27 2012 1325 1332
    • (2012) Int J Colorectal Dis , vol.27 , pp. 1325-1332
    • Sun, P.L.1    Li, B.2    Ye, Q.F.3
  • 10
    • 80053591096 scopus 로고    scopus 로고
    • Preoperative chemoradiation with cetuximab, irinotecan, and capecitabine in patients with locally advanced resectable rectal cancer: A multicenter Phase 2 study
    • S.Y. Kim, Y.S. Hong, and D.Y. Kim Preoperative chemoradiation with cetuximab, irinotecan, and capecitabine in patients with locally advanced resectable rectal cancer: a multicenter Phase 2 study Int J Radiat Oncol Biol Phys 81 2011 677 683
    • (2011) Int J Radiat Oncol Biol Phys , vol.81 , pp. 677-683
    • Kim, S.Y.1    Hong, Y.S.2    Kim, D.Y.3
  • 11
    • 84867305859 scopus 로고    scopus 로고
    • Cetuximab in preoperative treatment of rectal cancer - Term outcome of the XERT trial
    • V. Velenik, J. Ocvirk, and I. Oblak Cetuximab in preoperative treatment of rectal cancer - term outcome of the XERT trial Radiol Oncol 46 2012 252 257
    • (2012) Radiol Oncol , vol.46 , pp. 252-257
    • Velenik, V.1    Ocvirk, J.2    Oblak, I.3
  • 12
    • 74049108229 scopus 로고    scopus 로고
    • Molecular response to cetuximab and efficacy of preoperative cetuximab-based chemoradiation in rectal cancer
    • A. Debucquoy, K. Haustermans, and A. Daemen Molecular response to cetuximab and efficacy of preoperative cetuximab-based chemoradiation in rectal cancer J Clin Oncol 27 2009 2751 2757
    • (2009) J Clin Oncol , vol.27 , pp. 2751-2757
    • Debucquoy, A.1    Haustermans, K.2    Daemen, A.3
  • 13
    • 33750357154 scopus 로고    scopus 로고
    • Integration of EGFR inhibitors with radiochemotherapy
    • M.K. Nyati, M.A. Morgan, and F.Y. Feng Integration of EGFR inhibitors with radiochemotherapy Nat Rev Cancer 6 2006 876 885
    • (2006) Nat Rev Cancer , vol.6 , pp. 876-885
    • Nyati, M.K.1    Morgan, M.A.2    Feng, F.Y.3
  • 14
    • 77951272037 scopus 로고    scopus 로고
    • Cetuximab and chemoradiation for rectal cancer - Is the water getting muddy?
    • R. Glynne-Jones, S. Mawdsley, and M. Harrison Cetuximab and chemoradiation for rectal cancer - is the water getting muddy? Acta Oncol 49 2010 278 286
    • (2010) Acta Oncol , vol.49 , pp. 278-286
    • Glynne-Jones, R.1    Mawdsley, S.2    Harrison, M.3
  • 15
    • 80255141845 scopus 로고    scopus 로고
    • KRAS and BRAF mutations and PTEN expression do not predict efficacy of cetuximab-based chemoradiotherapy in locally advanced rectal cancer
    • P. Erben, P. Strobel, and K. Horisberger KRAS and BRAF mutations and PTEN expression do not predict efficacy of cetuximab-based chemoradiotherapy in locally advanced rectal cancer Int J Radiat Oncol Biol Phys 81 2011 1032 1038
    • (2011) Int J Radiat Oncol Biol Phys , vol.81 , pp. 1032-1038
    • Erben, P.1    Strobel, P.2    Horisberger, K.3
  • 16
    • 61649088414 scopus 로고    scopus 로고
    • Epidermal growth factor receptor gene copy number, K-ras mutation and pathological response to preoperative cetuximab, 5-FU and radiation therapy in locally advanced rectal cancer
    • C. Bengala, S. Bettelli, and F. Bertolini Epidermal growth factor receptor gene copy number, K-ras mutation and pathological response to preoperative cetuximab, 5-FU and radiation therapy in locally advanced rectal cancer Ann Oncol 20 2009 469 474
    • (2009) Ann Oncol , vol.20 , pp. 469-474
    • Bengala, C.1    Bettelli, S.2    Bertolini, F.3
  • 17
    • 0030990974 scopus 로고    scopus 로고
    • Pathological features of rectal cancer after preoperative radiochemotherapy
    • O. Dworak, L. Keilholz, and A. Hoffmann Pathological features of rectal cancer after preoperative radiochemotherapy Int J Colorectal Dis 12 1997 19 23
    • (1997) Int J Colorectal Dis , vol.12 , pp. 19-23
    • Dworak, O.1    Keilholz, L.2    Hoffmann, A.3
  • 18
    • 9744250225 scopus 로고    scopus 로고
    • Thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase expression, and histological tumour regression after 5-FU-based neo-adjuvant chemoradiotherapy in rectal cancer
    • C. Jakob, D.E. Aust, and W. Meyer Thymidylate synthase, thymidine phosphorylase, dihydropyrimidine dehydrogenase expression, and histological tumour regression after 5-FU-based neo-adjuvant chemoradiotherapy in rectal cancer J Pathol 204 2004 562 568
    • (2004) J Pathol , vol.204 , pp. 562-568
    • Jakob, C.1    Aust, D.E.2    Meyer, W.3
  • 19
    • 0027447928 scopus 로고
    • Simple technique for detecting RNA viruses by PCR in single sections of wax embedded tissue
    • C.J. Woodall, N.J. Watt, and G.B. Clements Simple technique for detecting RNA viruses by PCR in single sections of wax embedded tissue J Clin Pathol 46 1993 276 277
    • (1993) J Clin Pathol , vol.46 , pp. 276-277
    • Woodall, C.J.1    Watt, N.J.2    Clements, G.B.3
  • 20
    • 0030726659 scopus 로고    scopus 로고
    • Laser capture microdissection: Molecular analysis of tissue
    • R.F. Bonner, M. Emmert-Buck, and K. Cole Laser capture microdissection: molecular analysis of tissue Science 278 1997 1481 1483
    • (1997) Science , vol.278 , pp. 1481-1483
    • Bonner, R.F.1    Emmert-Buck, M.2    Cole, K.3
  • 21
    • 77954123084 scopus 로고    scopus 로고
    • Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors
    • S. Merkelbach-Bruse, W. Dietmaier, and L. Fuzesi Pitfalls in mutational testing and reporting of common KIT and PDGFRA mutations in gastrointestinal stromal tumors BMC Med Genet 11 2010 106
    • (2010) BMC Med Genet , vol.11 , pp. 106
    • Merkelbach-Bruse, S.1    Dietmaier, W.2    Fuzesi, L.3
  • 22
    • 27744566164 scopus 로고    scopus 로고
    • Pathological complete response following pre-operative chemoradiotherapy in rectal cancer: Analysis of phase II/III trials
    • A. Hartley, K.F. Ho, and C. McConkey Pathological complete response following pre-operative chemoradiotherapy in rectal cancer: analysis of phase II/III trials Br J Radiol 78 2005 934 938
    • (2005) Br J Radiol , vol.78 , pp. 934-938
    • Hartley, A.1    Ho, K.F.2    McConkey, C.3
  • 23
    • 77956185901 scopus 로고    scopus 로고
    • Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: A pooled analysis of individual patient data
    • M. Maas, P.J. Nelemans, and V. Valentini Long-term outcome in patients with a pathological complete response after chemoradiation for rectal cancer: a pooled analysis of individual patient data Lancet Oncol 11 2010 835 844
    • (2010) Lancet Oncol , vol.11 , pp. 835-844
    • Maas, M.1    Nelemans, P.J.2    Valentini, V.3
  • 24
    • 84863743780 scopus 로고    scopus 로고
    • Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C)
    • A. Dewdney, D. Cunningham, and J. Tabernero Multicenter randomized phase II clinical trial comparing neoadjuvant oxaliplatin, capecitabine, and preoperative radiotherapy with or without cetuximab followed by total mesorectal excision in patients with high-risk rectal cancer (EXPERT-C) J Clin Oncol 30 2012 1620 1627
    • (2012) J Clin Oncol , vol.30 , pp. 1620-1627
    • Dewdney, A.1    Cunningham, D.2    Tabernero, J.3
  • 25
    • 77952374261 scopus 로고    scopus 로고
    • Integration of epidermal growth factor receptor inhibitors with preoperative chemoradiation
    • A. Debucquoy, J.P. Machiels, and W.H. McBride Integration of epidermal growth factor receptor inhibitors with preoperative chemoradiation Clin Cancer Res 16 2010 2709 2714
    • (2010) Clin Cancer Res , vol.16 , pp. 2709-2714
    • Debucquoy, A.1    Machiels, J.P.2    McBride, W.H.3
  • 26
    • 80155136973 scopus 로고    scopus 로고
    • Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (StarPan/STAR-02 Study)
    • C. Pinto, F. Di Fabio, and E. Maiello Phase II study of panitumumab, oxaliplatin, 5-fluorouracil, and concurrent radiotherapy as preoperative treatment in high-risk locally advanced rectal cancer patients (StarPan/STAR-02 Study) Ann Oncol 22 2011 2424 2430
    • (2011) Ann Oncol , vol.22 , pp. 2424-2430
    • Pinto, C.1    Di Fabio, F.2    Maiello, E.3
  • 27
    • 74549208605 scopus 로고    scopus 로고
    • KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy
    • J. Gaedcke, M. Grade, and K. Jung KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy Radiother Oncol 94 2010 76 81
    • (2010) Radiother Oncol , vol.94 , pp. 76-81
    • Gaedcke, J.1    Grade, M.2    Jung, K.3
  • 28
    • 84871396704 scopus 로고    scopus 로고
    • KRAS mutation status and clinical outcome of preoperative chemoradiation with cetuximab in locally advanced rectal cancer: A pooled analysis of 2 phase II trials
    • S.Y. Kim, E.K. Shim, and H.Y. Yeo KRAS mutation status and clinical outcome of preoperative chemoradiation with cetuximab in locally advanced rectal cancer: a pooled analysis of 2 phase II trials Int J Radiat Oncol Biol Phys 85 2013 201 207
    • (2013) Int J Radiat Oncol Biol Phys , vol.85 , pp. 201-207
    • Kim, S.Y.1    Shim, E.K.2    Yeo, H.Y.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.