Individually optimized hemodynamic therapy reduces complications and length of stay in the intensive care unit: A prospective, randomized controlled trial

Anesthesiology

Volumn 119, Issue 4, 2013, Pages 824-836

  Goepfert, Matthias S ^a   Richter, Hans Peter ^a   Zu Eulenburg, Christine ^a   Gruetzmacher, Janna ^a   Rafflenbeul, Erik ^a   Roeher, Katharina ^a   Von Sandersleben, Alexandra ^a   Diedrichs, Stefan ^a   Reichenspurner, Herrmann ^a   Goetz, Alwin E ^a   Reuter, Daniel A ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

MIDAZOLAM; NORADRENALIN; PANCURONIUM BROMIDE; PROPOFOL; SEVOFLURANE; SUFENTANIL;

ADULT; AORTA VALVE REPLACEMENT; ARTICLE; BREATHING; CARDIOPULMONARY BYPASS; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; ENDOTRACHEAL INTUBATION; FEMALE; HEART ARRHYTHMIA; HEART INDEX; HEART STROKE VOLUME; HEART SURGERY; HEMODYNAMIC PARAMETERS; HEMODYNAMIC THERAPY; HUMAN; HYPERVOLEMIA; HYPOTHERMIA; INTENSIVE CARE UNIT; INTRAOPERATIVE PERIOD; LENGTH OF STAY; LUNG EDEMA; MAJOR CLINICAL STUDY; MALE; MEAN ARTERIAL PRESSURE; OPEN STUDY; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION;

ADRENERGIC ALPHA-AGONISTS; AGED; AORTIC VALVE; ARTERIAL PRESSURE; CARDIAC SURGICAL PROCEDURES; CENTRAL VENOUS PRESSURE; CORONARY ARTERY BYPASS; DIASTOLE; EPINEPHRINE; FEMALE; HEMODYNAMICS; HUMANS; HYDROXYETHYL STARCH DERIVATIVES; INTENSIVE CARE UNITS; ISOTONIC SOLUTIONS; LENGTH OF STAY; MALE; PLASMA SUBSTITUTES; POSTOPERATIVE COMPLICATIONS; PROSPECTIVE STUDIES; STROKE VOLUME;

EID: 84888292780     PISSN: 00033022     EISSN: 15281175     Source Type: Journal    
DOI: 10.1097/ALN.0b013e31829bd770     Document Type: Article

References (46)

1. Shoemaker WC, Appel PL, Kram HB, Waxman K, Lee TS: Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients. Chest 1988; 94:1176-86
2. Gattinoni L, Brazzi L, Pelosi P, Latini R, Tognoni G, Pesenti A, Fumagalli R: A trial of goal-oriented hemodynamic therapy in critically ill patients. SvO2 Collaborative Group. N Engl J Med 1995; 333:1025-32
3. Hayes MA, Timmins AC, Yau EH, Palazzo M, Hinds CJ, Watson D: Elevation of systemic oxygen delivery in the treatment of critically ill patients. N Engl J Med 1994; 330:1717-22
4. Shoemaker WC, Montgomery ES, Kaplan E, Elwyn DH: Physiologic patterns in surviving and nonsurviving shock patients. Use of sequential cardiorespiratory variables in defining criteria for therapeutic goals and early warning of death. Arch Surg 1973; 106:630-6
5. Kern JW, Shoemaker WC: Meta-analysis of hemodynamic optimization in high-risk patients. Crit Care Med 2002; 30:1686-92
6. Hamilton MA, Cecconi M, Rhodes A: A systematic review and meta-analysis on the use of preemptive hemodynamic intervention to improve postoperative outcomes in moderate and high-risk surgical patients. Anesth Analg 2011; 112:1392-402
7. Rivers E, Nguyen B, Havstad S, Ressler J, Muzzin A, Knoblich B, Peterson E, Tomlanovich M; Early Goal-Directed Therapy Collaborative Group: Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001; 345:1368-77
8. Mythen MG, Webb AR: Intra-operative gut mucosal hypoperfusion is associated with increased post-operative complications and cost. Intensive Care Med 1994; 20:99-4
9. Pölönen P, Ruokonen E, Hippeläinen M, Pöyhönen M, Takala J: A prospective, randomized study of goal-oriented hemodynamic therapy in cardiac surgical patients. Anesth Analg 2000; 90:1052-9
10. Gan TJ, Soppitt A, Maroof M, el-Moalem H, Robertson KM, Moretti E, Dwane P, Glass PS: Goal-directed intraoperative fluid administration reduces length of hospital stay after major surgery. Anesthesio logy 2002; 97:820-6
11. McKendry M, McGloin H, Saberi D, Caudwell L, Brady AR, Singer M: Randomised controlled trial assessing the impact of a nurse delivered, flow monitored protocol for optimisation of circulatory status after cardiac surgery. BMJ 2004; 329:258
12. Wakeling HG, McFall MR, Jenkins CS, Woods WG, Miles WF, Barclay GR, Fleming SC: Intraoperative oesophageal Doppler guided fluid management shortens postoperative hospital stay after major bowel surgery. Br J Anaesth 2005; 95:634-42
13. Goepfert MS, Reuter DA, Akyol D, Lamm P, Kilger E, Goetz AE: Goal-directed fluid management reduces vasopressor and catecholamine use in cardiac surgery patients. Intensive Care Med 2007; 33:96-3
14. Yu M, Burchell S, Hasaniya NW, Takanishi DM, Myers SA, Takiguchi SA: Relationship of mortality to increasing oxygen delivery in patients > or = 50 years of age: A prospective, randomized trial. Crit Care Med 1998; 26:1011-9
15. Yu M, Levy MM, Smith P, Takiguchi SA, Miyasaki A, Myers SA: Effect of maximizing oxygen delivery on morbidity and mortality rates in critically ill patients: A prospective, randomized, controlled study. Crit Care Med 1993; 21:830-8
16. Pearse R, Dawson D, Fawcett J, Rhodes A, Grounds RM, Bennett ED: Early goal-directed therapy after major surgery reduces complications and duration of hospital stay. A randomised, controlled trial [ISRCTN38797445]. Crit Care 2005; 9:R687-93
17. Jhanji S, Vivian-Smith A, Lucena-Amaro S, Watson D, Hinds CJ, Pearse RM: Haemodynamic optimisation improves tissue microvascular flow and oxygenation after major surgery: A randomised controlled trial. Crit Care 2010; 14:R151
18. Pinsky MR, Teboul JL: Assessment of indices of preload and volume responsiveness. Curr Opin Crit Care 2005; 11:235-9
19. Auler JO Jr, Galas F, Hajjar L, Santos L, Carvalho T, Michard F: Online monitoring of pulse pressure variation to guide fluid therapy after cardiac surgery. Anesth Analg 2008; 106:1201-6
20. Reuter DA, Kirchner A, Felbinger TW, Weis FC, Kilger E, Lamm P, Goetz AE: Usefulness of left ventricular stroke volume variation to assess fluid responsiveness in patients with reduced cardiac function. Crit Care Med 2003; 31:1399-404
21. Michard F, Alaya S, Zarka V, Bahloul M, Richard C, Teboul JL: Global end-diastolic volume as an indicator of cardiac preload in patients with septic shock. Chest 2003; 124:1900-8
22. Brock H, Gabriel C, Bibl D, Necek S: Monitoring intravascular volumes for postoperative volume therapy. Eur J Anaesthesiol 2002; 19:288-94
23. Reuter DA, Felbinger TW, Moerstedt K, Weis F, Schmidt C, Kilger E, Goetz AE: Intrathoracic blood volume index measured by thermodilution for preload monitoring after cardiac surgery. J Cardiothorac Vasc Anesth 2002; 16:191-5
24. Muller L, Louart G, Bengler C, Fabbro-Peray P, Carr J, Ripart J, de La Coussaye JE, Lefrant JY: The intrathoracic blood volume index as an indicator of fluid responsiveness in critically ill patients with acute circulatory failure: A comparison with central venous pressure. Anesth Analg 2008; 107:607-13
25. Wolf S, Riess A, Landscheidt JF, Lumenta CB, Friederich P, Schürer L: Global end-diastolic volume acquired by transpulmonary thermodilution depends on age and gender in awake and spontaneously breathing patients. Crit Care 2009; 13:R202
26. Malbrain ML, De Potter TJ, Dits H, Reuter DA: Global and right ventricular end-diastolic volumes correlate better with preload after correction for ejection fraction. Acta Anaesthesiol Scand 2010; 54:622-31
27. Sakka SG, Meier-Hellmann A: Extremely high values of intrathoracic blood volume in critically ill patients. Intensive Care Med 2001; 27:1677-8
28. Eichhorn V, Goepfert MS, Eulenburg C, Malbrain ML, Reuter DA: Comparison of values in critically ill patients for global end-diastolic volume and extravascular lung water measured by transcardiopulmonary thermodilution: A meta-analysis of the literature. Med Intensiva 2012; 36:467-74
29. Zöllner C, Haller M, Weis M, Mörstedt K, Lamm P, Kilger E, Goetz AE: Beat-to-beat measurement of cardiac output by intravascular pulse contour analysis: A prospective criterion standard study in patients after cardiac surgery. J Cardiothorac Vasc Anesth 2000; 14:125-9
30. Gödje O, Höke K, Goetz AE, Felbinger TW, Reuter DA, Reichart B, Friedl R, Hannekum A, Pfeiffer UJ: Reliability of a new algorithm for continuous cardiac output determination by pulse-contour analysis during hemodynamic instability. Crit Care Med 2002; 30:52-8
31. Sakka SG, Klein M, Reinhart K, Meier-Hellmann A: Prognostic value of extravascular lung water in critically ill patients. Chest 2002; 122:2080-6
32. Phillips CR, Chesnutt MS, Smith SM: Extravascular lung water in sepsis-associated acute respiratory distress syndrome: Indexing with predicted body weight improves correlation with severity of illness and survival. Crit Care Med 2008; 36:69-3
33. Carl M, Alms A, Braun J, Dongas A, Erb J, Goetz A, Goepfert M, Gogarten W, Grosse J, Heller AR, Heringlake M, Kastrup M, Kroener A, Loer SA, Marggraf G, Markewitz A, Reuter D, Schmitt DV, Schirmer U, Wiesenack C, Zwissler B, Spies C: Guidelines for intensive care in cardiac surgery patients: Haemodynamic monitoring and cardio-circulatory treatment guidelines of the German Society for Thoracic and Cardiovascular Surgery and the German Society of Anaesthesiology and Intensive Care Medicine. Thorac Cardiovasc Surg 2007; 55:130-48
34. Gaudreau JD, Gagnon P, Harel F, Tremblay A, Roy MA: Fast, systematic, and continuous delirium assessment in hospitalized patients: The nursing delirium screening scale. J Pain Symptom Manage 2005; 29:368-75
35. Mehta RL, Kellum JA, Shah SV, Molitoris BA, Ronco C, Warnock DG, Levin A; Acute Kidney Injury Network: Acute Kidney Injury Network: Report of an initiative to improve outcomes in acute kidney injury. Crit Care 2007; 11:R31
36. Cheng DC, Newman MF, Duke P, Wong DT, Finegan B, Howie M, Fitch J, Bowdle TA, Hogue C, Hillel Z, Pierce E, Bukenya D: The efficacy and resource utilization of remifentanil and fentanyl in fast-track coronary artery bypass graft surgery: A prospective randomized, double-blinded controlled, multicenter trial. Anesth Analg 2001; 92:1094-102
37. Ghanta RK, Shekar PS, McGurk S, Rosborough DM, Aranki SF: Long-term survival and quality of life justify cardiac surgery in the very elderly patient. Ann Thorac Surg 2011; 92:851-7
38. Smetkin AA, Kirov MY, Kuzkov VV, Lenkin AI, Eremeev AV, Slastilin VY, Borodin VV, Bjertnaes LJ: Single transpulmonary thermodilution and continuous monitoring of central venous oxygen saturation during off-pump coronary surgery. Acta Anaesthesiol Scand 2009; 53:505-14
39. Kortgen A, Niederprüm P, Bauer M: Implementation of an evidence-based "standard operating procedure" and outcome in septic shock. Crit Care Med 2006; 34:943-9
40. Takala J, Ruokonen E, Tenhunen JJ, Parviainen I, Jakob SM: Early non-invasive cardiac output monitoring in hemodynamically unstable intensive care patients: A multi-center randomized controlled trial. Crit Care 2011; 15:R148
41. Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL; International Surviving Sepsis Campaign Guidelines Committee; American Association of Critical-Care Nurses; American College of Chest Physicians; American College of Emergency Physicians; Canadian Critical Care Society; European Society of Clinical Microbiology and Infectious Diseases; European Society of Intensive Care Medicine; European Respiratory Society; International Sepsis Forum; Japanese Association for Acute Medicine; Japanese Society of Intensive Care Medicine; Society of Critical Care Medicine; Society of Hospital Medicine; Surgical Infection Society; World Federation of Societies of Intensive and Critical Care Medicine: Surviving Sepsis Campaign: International guidelines for management of severe sepsis and septic shock: 2008. Crit Care Med 2008; 36:296-327
42. Reuter DA, Felbinger TW, Schmidt C, Kilger E, Goedje O, Lamm P, Goetz AE: Stroke volume variations for assessment of cardiac responsiveness to volume loading in mechanically ventilated patients after cardiac surgery. Intensive Care Med 2002; 28:392-8
43. Rex S, Brose S, Metzelder S, Hüneke R, Schälte G, Autschbach R, Rossaint R, Buhre W: Prediction of fluid responsiveness in patients during cardiac surgery. Br J Anaesth 2004; 93:782-8
44. Hofer CK, Müller SM, Furrer L, Klaghofer R, Genoni M, Zollinger A: Stroke volume and pulse pressure variation for prediction of fluid responsiveness in patients undergoing off-pump coronary artery bypass grafting. Chest 2005; 128:848-54
45. Perner A, Haase N, Guttormsen AB, Tenhunen J, Klemenzson G, Åneman A, Madsen KR, Møller MH, Elkjar JM, Poulsen LM, Bendtsen A, Winding R, Steensen M, Berezowicz P, Søe- Jensen P, Bestle M, Strand K, Wiis J, White JO, Thornberg KJ, Quist L, Nielsen J, Andersen LH, Holst LB, Thormar K, Kjaldgaard AL, Fabritius ML, Mondrup F, Pott FC, Møller TP, Winkel P, Wetterslev J; 6S Trial Group; Scandinavian Critical Care Trials Group: Hydroxyethyl starch 130/0.42 versus Ringer's acetate in severe sepsis. N Engl J Med 2012; 367:124-34
46. Myburgh JA, Finfer S, Bellomo R, Billot L, Cass A, Gattas D, Glass P, Lipman J, Liu B, McArthur C, McGuinness S, Rajbhandari D, Taylor CB, Webb SA; CHEST Investigators; Australian and New Zealand Intensive Care Society Clinical Trials Group: Hydroxyethyl starch or saline for fluid resuscitation in intensive care. N Engl J Med 2012; 367:1901-11