Hepatic loss of miR-122 predisposes mice to hepatobiliary cyst and hepatocellular carcinoma upon diethylnitrosamine exposure

American Journal of Pathology

Volumn 183, Issue 6, 2013, Pages 1719-1730

  Hsu, Shu Hao ^a   Wang, Bo ^a   Kutay, Huban ^b   Bid, Hemant ^b,c   Shreve, Julia ^b   Zhang, Xiaoli ^a,b   Costinean, Stefan ^a   Bratasz, Anna ^b   Houghton, Peter ^b,c   Ghoshal, Kalpana ^a,c,d  

^a OHIO STATE UNIVERSITY   (United States)

^b OHIO STATE UNIVERSITY   (United States)

^c NATIONWIDE CHILDREN S HOSPITAL   (United States)

^d THE OHIO STATE UNIVERSITY COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOKINE; DIETHYLNITROSAMINE; MICRORNA 122; PROTEIN TYROSINE PHOSPHATASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AXL ONCOGENE; BILE DUCT CYST; CONTROLLED STUDY; DISEASE PREDISPOSITION; HEPATOBILIARY CYST; LIVER ADENOMA; LIVER CARCINOGENESIS; LIVER CELL CARCINOMA; LIVER TUMOR; MOUSE; NONHUMAN; ONCOGENE; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; UPREGULATION;

ALKYLATING AGENTS; ANIMALS; CARCINOMA, HEPATOCELLULAR; CDC25 PHOSPHATASES; CELL PROLIFERATION; CYSTS; CYTOKINES; DIETHYLNITROSAMINE; E2F1 TRANSCRIPTION FACTOR; GENE EXPRESSION REGULATION, NEOPLASTIC; LIVER NEOPLASMS; MICE; MICE, KNOCKOUT; MICRORNAS; NEOPLASM METASTASIS; PROTO-ONCOGENE PROTEINS; RECEPTOR PROTEIN-TYROSINE KINASES; SIGNAL TRANSDUCTION;

EID: 84888245340     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2013.08.004     Document Type: Article

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