Comparison of two approaches for quantitative O-linked glycan analysis used in characterization of recombinant proteins

Analytical Biochemistry

Volumn 446, Issue 1, 2014, Pages 28-36

  Turyan, Iva ^a   Hronowski, Xiaoping ^a   Sosic, Zoran ^a   Lyubarskaya, Yelena ^a  

^a BIOGEN   (United States)

Author keywords

HILIC; LTQ FT MS; O linked glycan analysis

Indexed keywords

AMMONIA; GLYCOPROTEINS; HYDROPHILICITY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; REAGENTS; RECOMBINANT PROTEINS;

DEGLYCOSYLATION; FOURIER TRANSFORM MASS SPECTROMETRY; GLYCAN ANALYSIS; HILIC; HYDROPHILIC INTERACTION CHROMATOGRAPHY; LTQ FT MS; PERFORMANCE PARAMETERS; STRUCTURE ELUCIDATION;

POLYSACCHARIDES;

AMMONIA; GLYCAN; HYDRAZINE; RECOMBINANT PROTEIN;

ACIDIFICATION; ARTICLE; CONTROLLED STUDY; DEGLYCOSYLATION; DERIVATIZATION; ELIMINATION REACTION; FOURIER TRANSFORM MASS SPECTROMETRY; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILIC INTERACTION CHROMATOGRAPHY; ION EXCHANGE CHROMATOGRAPHY; ION TRAP MASS SPECTROMETRY; LIMIT OF QUANTITATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; QUANTITATIVE ANALYSIS; REVERSED PHASE LIQUID CHROMATOGRAPHY; TANDEM MASS SPECTROMETRY;

HILIC; LTQ FT MS; O-LINKED GLYCAN ANALYSIS;

AMMONIA; CHROMATOGRAPHY; GLYCOPROTEINS; GLYCOSYLATION; HUMANS; HYDRAZINES; MASS SPECTROMETRY; OXYGEN; POLYSACCHARIDES; RECOMBINANT PROTEINS;

EID: 84888226286     PISSN: 00032697     EISSN: 10960309     Source Type: Journal    
DOI: 10.1016/j.ab.2013.10.019     Document Type: Article

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