Deletion of the α-(1,3)-Glucan Synthase Genes Induces a Restructuring of the Conidial Cell Wall Responsible for the Avirulence of Aspergillus fumigatus

PLoS Pathogens

Volumn 9, Issue 11, 2013, Pages

  Beauvais, Anne ^a   Bozza, Silvia ^b   Kniemeyer, Olaf ^c,d   Formosa, Céline ^e   Balloy, Viviane ^a   Henry, Christine ^a   Roberson, Robert W ^f   Dague, Etienne ^e   Chignard, Michel ^a   Brakhage, Axel A ^c   Romani, Luigina ^b   Latgé, Jean Paul ^a  

^a INSTITUT PASTEUR   (France)

^b UNIVERSITY OF PERUGIA   (Italy)

^c FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

^d JENA UNIVERSITY HOSPITAL   (Germany)

^e LAAS CNRS   (France)

^f ARIZONA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATHELICIDIN ANTIMICROBIAL PEPTIDE LL 37; CYCLOPHOSPHAMIDE; GALACTOMANNAN; GLYCOPROTEIN; HYDROFLUORIC ACID; INTERLEUKIN 10; LACTOFERRIN; TUMOR NECROSIS FACTOR ALPHA;

1, 3 ALPHA GLUCAN SYNTHASE GENE; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CHEMICAL ANALYSIS; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FLUORESCENCE MICROSCOPY; FUNGAL CELL WALL; GENE; GENE DELETION; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; MOUSE; NONHUMAN; OXIDATIVE STRESS; PHAGOCYTOSIS; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SURFACE PROPERTY; TRANSMISSION ELECTRON MICROSCOPY; VIRULENCE;

ANIMALS; ASPERGILLOSIS; ASPERGILLUS FUMIGATUS; CELL WALL; FUNGAL POLYSACCHARIDES; FUNGAL PROTEINS; GENE DELETION; GLUCOSYLTRANSFERASES; HUMANS; MICE, KNOCKOUT; SPORES, FUNGAL;

EID: 84888214435     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1003716     Document Type: Article

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