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Volumn 32, Issue 1, 2014, Pages 21-32

The Renin-Angiotensin-Aldosterone System and Heart Failure

Author keywords

Aldosterone; Angiotensin II; Angiotensin converting enzyme inhibitors; Angiotensin receptor blockers; Heart failure; Neurohormonal; Renin angiotensin aldosterone system

Indexed keywords

ALDOSTERONE; ALDOSTERONE ANTAGONIST; ALISKIREN; ANGIOTENSIN II; ANGIOTENSIN RECEPTOR ANTAGONIST; CANDESARTAN; CAPTOPRIL; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; ENALAPRIL; EPLERENONE; HYDRALAZINE PLUS ISOSORBIDE DINITRATE; LISINOPRIL; LOSARTAN; PERINDOPRIL; PLACEBO; RAMIPRIL; RENIN INHIBITOR; SPIRONOLACTONE; TRANDOLAPRIL; VALSARTAN;

EID: 84888212540     PISSN: 07338651     EISSN: 15582264     Source Type: Journal    
DOI: 10.1016/j.ccl.2013.09.002     Document Type: Review
Times cited : (150)

References (69)
  • 1
    • 0028955321 scopus 로고
    • Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure
    • Garg R., Yusuf S. Overview of randomized trials of angiotensin-converting enzyme inhibitors on mortality and morbidity in patients with heart failure. JAMA 1995, 273:1450-1456.
    • (1995) JAMA , vol.273 , pp. 1450-1456
    • Garg, R.1    Yusuf, S.2
  • 2
    • 35448957699 scopus 로고    scopus 로고
    • Comparison of the beneficial effect of beta-blockers on mortality in patients with ischaemic or non-ischaemic systolic heart failure: a meta-analysis of randomized controlled trials
    • Fauchier L., Pierre B., de Labriolle A., et al. Comparison of the beneficial effect of beta-blockers on mortality in patients with ischaemic or non-ischaemic systolic heart failure: a meta-analysis of randomized controlled trials. Eur J Heart Fail 2007, 9:1136-1139.
    • (2007) Eur J Heart Fail , vol.9 , pp. 1136-1139
    • Fauchier, L.1    Pierre, B.2    de Labriolle, A.3
  • 3
    • 0021828444 scopus 로고
    • Survival after an experimental myocardial infarction: beneficial effects of long-term therapy with captopril
    • Pfeffer M.A., Pfeffer J.M., Steinberg C., et al. Survival after an experimental myocardial infarction: beneficial effects of long-term therapy with captopril. Circulation 1985, 72(2):406-412.
    • (1985) Circulation , vol.72 , Issue.2 , pp. 406-412
    • Pfeffer, M.A.1    Pfeffer, J.M.2    Steinberg, C.3
  • 4
    • 84884294190 scopus 로고    scopus 로고
    • 2013 ACCF/AHA guideline for the management of heart failure
    • Yancy C.W., Jessup M., Bozkurt B., et al. 2013 ACCF/AHA guideline for the management of heart failure. JAm Coll Cardiol 2013, 10.1016/j.jacc.2013.05.019.
    • (2013) JAm Coll Cardiol
    • Yancy, C.W.1    Jessup, M.2    Bozkurt, B.3
  • 5
    • 84864493727 scopus 로고    scopus 로고
    • ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012
    • McMurray J.J., Adamopoulos S., Anker S.D., et al. ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure 2012. Eur Heart J 2012, 33:1787-1847.
    • (2012) Eur Heart J , vol.33 , pp. 1787-1847
    • McMurray, J.J.1    Adamopoulos, S.2    Anker, S.D.3
  • 6
    • 77953593318 scopus 로고    scopus 로고
    • HFSA 2010 Comprehensive Heart Failure Practice Guideline
    • Lindenfeld J., Albert N.M., Boehmer J.P., et al. HFSA 2010 Comprehensive Heart Failure Practice Guideline. JCard Fail 2010, 16:e1-e194.
    • (2010) JCard Fail , vol.16
    • Lindenfeld, J.1    Albert, N.M.2    Boehmer, J.P.3
  • 7
    • 0026571201 scopus 로고
    • Pressure dependent modulation of renin release in isolated perfused glomeruli
    • Bock H.A., Hermle M., Brunner F.P., et al. Pressure dependent modulation of renin release in isolated perfused glomeruli. Kidney Int 1992, 41:275-280.
    • (1992) Kidney Int , vol.41 , pp. 275-280
    • Bock, H.A.1    Hermle, M.2    Brunner, F.P.3
  • 8
    • 0025239660 scopus 로고
    • Angiotensin II-forming pathways in normal and failing human hearts
    • Urata H., Healy B., Stewart R.W., et al. Angiotensin II-forming pathways in normal and failing human hearts. Circ Res 1990, 66:883-890.
    • (1990) Circ Res , vol.66 , pp. 883-890
    • Urata, H.1    Healy, B.2    Stewart, R.W.3
  • 9
    • 0025165780 scopus 로고
    • Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat
    • Seikaly M.G., Arant B.S., Seney F.D. Endogenous angiotensin concentrations in specific intrarenal fluid compartments of the rat. JClin Invest 1990, 86:1352-1357.
    • (1990) JClin Invest , vol.86 , pp. 1352-1357
    • Seikaly, M.G.1    Arant, B.S.2    Seney, F.D.3
  • 10
    • 0032493428 scopus 로고    scopus 로고
    • Angiotensin production by the heart: a quantitative study in pigs with the use of radiolabeled angiotensin infusions
    • van Kats J.P., Danser A.H., van Meegen J.R., et al. Angiotensin production by the heart: a quantitative study in pigs with the use of radiolabeled angiotensin infusions. Circulation 1998, 98:73-81.
    • (1998) Circulation , vol.98 , pp. 73-81
    • van Kats, J.P.1    Danser, A.H.2    van Meegen, J.R.3
  • 11
    • 0027285976 scopus 로고
    • Tissue renin-angiotensin system in myocardial hypertrophy and failure
    • Dzau V.J. Tissue renin-angiotensin system in myocardial hypertrophy and failure. Arch Intern Med 1993, 153:937-942.
    • (1993) Arch Intern Med , vol.153 , pp. 937-942
    • Dzau, V.J.1
  • 12
    • 0024378763 scopus 로고
    • Interaction of vasopressin and angiotensin II in stimulation of prostacyclin synthesis in vascular smooth muscle cells
    • Vallotton M.B., Gerber-Wicht C., Dolci W., et al. Interaction of vasopressin and angiotensin II in stimulation of prostacyclin synthesis in vascular smooth muscle cells. Am J Physiol 1989, 257:E617-E624.
    • (1989) Am J Physiol , vol.257
    • Vallotton, M.B.1    Gerber-Wicht, C.2    Dolci, W.3
  • 13
    • 0025126437 scopus 로고
    • Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells
    • Baker K.M., Aceto J.F. Angiotensin II stimulation of protein synthesis and cell growth in chick heart cells. Am J Physiol 1990, 259:H610-H618.
    • (1990) Am J Physiol , vol.259
    • Baker, K.M.1    Aceto, J.F.2
  • 14
    • 0029869313 scopus 로고    scopus 로고
    • Plasma angiotensin II, predisposition to hypertension, and left ventricular size in healthy young adults
    • Harrap S.B., Dominiczak A.F., Fraser R., et al. Plasma angiotensin II, predisposition to hypertension, and left ventricular size in healthy young adults. Circulation 1996, 93:1148-1154.
    • (1996) Circulation , vol.93 , pp. 1148-1154
    • Harrap, S.B.1    Dominiczak, A.F.2    Fraser, R.3
  • 15
    • 0036945213 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis
    • Peng J., Gurantz D., Tran V., et al. Tumor necrosis factor-alpha-induced AT1 receptor upregulation enhances angiotensin II-mediated cardiac fibroblast responses that favor fibrosis. Circ Res 2002, 91:1119-1126.
    • (2002) Circ Res , vol.91 , pp. 1119-1126
    • Peng, J.1    Gurantz, D.2    Tran, V.3
  • 16
    • 0030657676 scopus 로고    scopus 로고
    • Extracellular matrix remodeling in heart failure: a role for de novo angiotensin II generation
    • Weber K.T. Extracellular matrix remodeling in heart failure: a role for de novo angiotensin II generation. Circulation 1997, 96:4065-4082.
    • (1997) Circulation , vol.96 , pp. 4065-4082
    • Weber, K.T.1
  • 17
    • 0025153828 scopus 로고
    • Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD)
    • Francis G.S., Benedict C., Johnstone D.E., et al. Comparison of neuroendocrine activation in patients with left ventricular dysfunction with and without congestive heart failure. A substudy of the Studies of Left Ventricular Dysfunction (SOLVD). Circulation 1990, 82:1724-1729.
    • (1990) Circulation , vol.82 , pp. 1724-1729
    • Francis, G.S.1    Benedict, C.2    Johnstone, D.E.3
  • 18
    • 18244379073 scopus 로고    scopus 로고
    • Mineralocorticoid receptor is overexpressed in cardiomyocytes of patients with congestive heart failure
    • Yoshida M., Ma J., Tomita T., et al. Mineralocorticoid receptor is overexpressed in cardiomyocytes of patients with congestive heart failure. Congest Heart Fail 2005, 11:12-16.
    • (2005) Congest Heart Fail , vol.11 , pp. 12-16
    • Yoshida, M.1    Ma, J.2    Tomita, T.3
  • 19
    • 0028275578 scopus 로고
    • Collagen metabolism in cultured adult rat cardiac fibroblasts: response to angiotensin II and aldosterone
    • Brilla C.G., Zhou G., Matsubara L., et al. Collagen metabolism in cultured adult rat cardiac fibroblasts: response to angiotensin II and aldosterone. JMol Cell Cardiol 1994, 26:809-820.
    • (1994) JMol Cell Cardiol , vol.26 , pp. 809-820
    • Brilla, C.G.1    Zhou, G.2    Matsubara, L.3
  • 20
    • 0035838423 scopus 로고    scopus 로고
    • Aldosterone induces angiotensin-converting-enzyme gene expression in cultured neonatal rat cardiocytes
    • Harada E., Yoshimura M., Yasue H., et al. Aldosterone induces angiotensin-converting-enzyme gene expression in cultured neonatal rat cardiocytes. Circulation 2001, 104:137-139.
    • (2001) Circulation , vol.104 , pp. 137-139
    • Harada, E.1    Yoshimura, M.2    Yasue, H.3
  • 21
    • 0006862091 scopus 로고    scopus 로고
    • Role of bradykinin inmediating vascular effects of angiotensin-converting enzyme inhibitors in humans
    • Hornig B., Kohler C., Drexler H. Role of bradykinin inmediating vascular effects of angiotensin-converting enzyme inhibitors in humans. Circulation 1997, 95:1115-1118.
    • (1997) Circulation , vol.95 , pp. 1115-1118
    • Hornig, B.1    Kohler, C.2    Drexler, H.3
  • 22
    • 0021363244 scopus 로고
    • Hemodynamic and clinical response to enalapril, a long-acting converting-enzyme inhibitor, in patients with congestive heart failure
    • Levine T.B., Olivari M.T., Garberg V., et al. Hemodynamic and clinical response to enalapril, a long-acting converting-enzyme inhibitor, in patients with congestive heart failure. Circulation 1984, 69:548-553.
    • (1984) Circulation , vol.69 , pp. 548-553
    • Levine, T.B.1    Olivari, M.T.2    Garberg, V.3
  • 23
    • 0023695285 scopus 로고
    • Modulation of hemodynamic effects with a converting enzyme inhibitor: acute hemodynamic dose-response relationship of a new angiotensin converting enzyme inhibitor, lisinopril, with observations on long-term clinical, functional, and biochemical responses
    • Uretsky B.F., Shaver J.A., Liang C.S., et al. Modulation of hemodynamic effects with a converting enzyme inhibitor: acute hemodynamic dose-response relationship of a new angiotensin converting enzyme inhibitor, lisinopril, with observations on long-term clinical, functional, and biochemical responses. Am Heart J 1988, 116:480-488.
    • (1988) Am Heart J , vol.116 , pp. 480-488
    • Uretsky, B.F.1    Shaver, J.A.2    Liang, C.S.3
  • 24
    • 0021968215 scopus 로고
    • Influence of chronic captopril therapy on the infarcted left ventricle of the rat
    • Pfeffer J.M., Pfeffer M.A., Braunwald E. Influence of chronic captopril therapy on the infarcted left ventricle of the rat. Circ Res 1985, 57:84-95.
    • (1985) Circ Res , vol.57 , pp. 84-95
    • Pfeffer, J.M.1    Pfeffer, M.A.2    Braunwald, E.3
  • 25
    • 0025759178 scopus 로고
    • Early prevention of left ventricular dysfunction after myocardial infarction with angiotensin-converting-enzyme inhibition
    • Sharpe N., Smith H., Murphy J., et al. Early prevention of left ventricular dysfunction after myocardial infarction with angiotensin-converting-enzyme inhibition. Lancet 1991, 337:872-876.
    • (1991) Lancet , vol.337 , pp. 872-876
    • Sharpe, N.1    Smith, H.2    Murphy, J.3
  • 26
    • 0028127720 scopus 로고
    • Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril
    • St John Sutton M., Pfeffer M.A., Plappert T., et al. Quantitative two-dimensional echocardiographic measurements are major predictors of adverse cardiovascular events after acute myocardial infarction. The protective effects of captopril. Circulation 1994, 89:68-75.
    • (1994) Circulation , vol.89 , pp. 68-75
    • St John Sutton, M.1    Pfeffer, M.A.2    Plappert, T.3
  • 27
    • 0026704692 scopus 로고
    • Effects of the angiotensin converting enzyme inhibitor enalapril on the long-term progression of left ventricular dysfunction in patients with heart failure
    • Konstam M.A., Rousseau M.F., Kronenberg M.W., et al. Effects of the angiotensin converting enzyme inhibitor enalapril on the long-term progression of left ventricular dysfunction in patients with heart failure. Circulation 1992, 86:431-438.
    • (1992) Circulation , vol.86 , pp. 431-438
    • Konstam, M.A.1    Rousseau, M.F.2    Kronenberg, M.W.3
  • 28
    • 0027482668 scopus 로고
    • Effects of the angiotensin converting enzyme inhibitor enalapril on the long-term progression of left ventricular dilatation in patients with asymptomatic systolic dysfunction
    • Konstam M.A., Kronenberg M.W., Rousseau M.F., et al. Effects of the angiotensin converting enzyme inhibitor enalapril on the long-term progression of left ventricular dilatation in patients with asymptomatic systolic dysfunction. Circulation 1993, 88:2277-2283.
    • (1993) Circulation , vol.88 , pp. 2277-2283
    • Konstam, M.A.1    Kronenberg, M.W.2    Rousseau, M.F.3
  • 29
    • 0023199927 scopus 로고
    • Enalapril for congestive heart failure
    • Enalapril for congestive heart failure. NEngl J Med 1987, 317:1349-1351.
    • (1987) NEngl J Med , vol.317 , pp. 1349-1351
  • 30
    • 0025913812 scopus 로고
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure
    • Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. NEngl J Med 1991, 325:293-302.
    • (1991) NEngl J Med , vol.325 , pp. 293-302
  • 31
    • 0026785561 scopus 로고
    • Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions
    • Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. NEngl J Med 1992, 327:685-691.
    • (1992) NEngl J Med , vol.327 , pp. 685-691
  • 32
    • 0026786643 scopus 로고
    • Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial
    • Pfeffer M.A., Braunwald E., Moye L.A., et al. Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. NEngl J Med 1992, 327:669-677.
    • (1992) NEngl J Med , vol.327 , pp. 669-677
    • Pfeffer, M.A.1    Braunwald, E.2    Moye, L.A.3
  • 33
    • 0027423378 scopus 로고
    • Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure
    • Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. Lancet 1993, 342:821-828.
    • (1993) Lancet , vol.342 , pp. 821-828
  • 34
    • 9044239676 scopus 로고
    • Aclinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction
    • Kober L., Torp-Pedersen C., Carlsen J.E., et al. Aclinical trial of the angiotensin-converting-enzyme inhibitor trandolapril in patients with left ventricular dysfunction after myocardial infarction. NEngl J Med 1995, 333:1670-1676.
    • (1995) NEngl J Med , vol.333 , pp. 1670-1676
    • Kober, L.1    Torp-Pedersen, C.2    Carlsen, J.E.3
  • 35
    • 0025770138 scopus 로고
    • Acomparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure
    • Cohn J.N., Johnson G., Ziesche S., et al. Acomparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. NEngl J Med 1991, 325:303-310.
    • (1991) NEngl J Med , vol.325 , pp. 303-310
    • Cohn, J.N.1    Johnson, G.2    Ziesche, S.3
  • 36
    • 0033534085 scopus 로고    scopus 로고
    • Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure
    • Packer M., Poole-Wilson P.A., Armstrong P.W., et al. Comparative effects of low and high doses of the angiotensin-converting enzyme inhibitor, lisinopril, on morbidity and mortality in chronic heart failure. Circulation 1999, 100:2312-2318.
    • (1999) Circulation , vol.100 , pp. 2312-2318
    • Packer, M.1    Poole-Wilson, P.A.2    Armstrong, P.W.3
  • 37
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients
    • Yusuf S., Sleight P., Pogue J., et al. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. NEngl J Med 2000, 342:145-153.
    • (2000) NEngl J Med , vol.342 , pp. 145-153
    • Yusuf, S.1    Sleight, P.2    Pogue, J.3
  • 38
    • 0042330455 scopus 로고    scopus 로고
    • Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomized, double-blind, placebo-controlled, multicentre trial (the EUROPA study)
    • EURopean trial On reduction of cardiac events with Perindopril in stable coronary Artery disease Investigators
    • Fox K.M., EURopean trial On reduction of cardiac events with Perindopril in stable coronary Artery disease Investigators Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomized, double-blind, placebo-controlled, multicentre trial (the EUROPA study). Lancet 2003, 362:782-788.
    • (2003) Lancet , vol.362 , pp. 782-788
    • Fox, K.M.1
  • 39
    • 19644400972 scopus 로고    scopus 로고
    • Angiotensin-converting-enzyme inhibition in stable coronary artery disease
    • Braunwald E., Domanski M.J., Fowler S.E., et al. Angiotensin-converting-enzyme inhibition in stable coronary artery disease. NEngl J Med 2004, 351:2058-2068.
    • (2004) NEngl J Med , vol.351 , pp. 2058-2068
    • Braunwald, E.1    Domanski, M.J.2    Fowler, S.E.3
  • 40
    • 33746863179 scopus 로고    scopus 로고
    • Angiotensin-converting-enzyme inhibitors in stable vascular disease without left ventricular systolic dysfunction or heart failure: a combined analysis of three trials
    • Dagenais G.R., Pogue J., Fox K., et al. Angiotensin-converting-enzyme inhibitors in stable vascular disease without left ventricular systolic dysfunction or heart failure: a combined analysis of three trials. Lancet 2006, 368:581-588.
    • (2006) Lancet , vol.368 , pp. 581-588
    • Dagenais, G.R.1    Pogue, J.2    Fox, K.3
  • 41
    • 0033117190 scopus 로고    scopus 로고
    • Dose-related beneficial long-term hemodynamic and clinical efficacy of irbesartan in heart failure
    • Havranek E.P., Thomas I., Smith W.B., et al. Dose-related beneficial long-term hemodynamic and clinical efficacy of irbesartan in heart failure. JAm Coll Cardiol 1999, 33:1174-1181.
    • (1999) JAm Coll Cardiol , vol.33 , pp. 1174-1181
    • Havranek, E.P.1    Thomas, I.2    Smith, W.B.3
  • 42
    • 0030881016 scopus 로고    scopus 로고
    • Comparative effects of losartan and enalapril on exercise capacity and clinical status in patients with heart failure
    • Lang R.M., Elkayam U., Yellen L.G., et al. Comparative effects of losartan and enalapril on exercise capacity and clinical status in patients with heart failure. JAm Coll Cardiol 1997, 30:983-991.
    • (1997) JAm Coll Cardiol , vol.30 , pp. 983-991
    • Lang, R.M.1    Elkayam, U.2    Yellen, L.G.3
  • 43
    • 0034612118 scopus 로고    scopus 로고
    • Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial-the Losartan Heart Failure Survival Study ELITE II
    • Pitt B., Poole-Wilson P.A., Segal R., et al. Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial-the Losartan Heart Failure Survival Study ELITE II. Lancet 2000, 355:1582-1587.
    • (2000) Lancet , vol.355 , pp. 1582-1587
    • Pitt, B.1    Poole-Wilson, P.A.2    Segal, R.3
  • 44
    • 0037036971 scopus 로고    scopus 로고
    • Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial
    • OPTIMAAL Steering Committee of the OPTIMAAL Study Group
    • Dickstein K., Kjekshus J., OPTIMAAL Steering Committee of the OPTIMAAL Study Group Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial. Lancet 2002, 360:752-760.
    • (2002) Lancet , vol.360 , pp. 752-760
    • Dickstein, K.1    Kjekshus, J.2
  • 45
    • 0242490542 scopus 로고    scopus 로고
    • Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both
    • Pfeffer M.A., McMurray J.J., Velazquez E.J., et al. Valsartan, captopril, or both in myocardial infarction complicated by heart failure, left ventricular dysfunction, or both. NEngl J Med 2003, 349:1893-1906.
    • (2003) NEngl J Med , vol.349 , pp. 1893-1906
    • Pfeffer, M.A.1    McMurray, J.J.2    Velazquez, E.J.3
  • 46
    • 0041909380 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial
    • Granger C.B., McMurray J.J., Yusuf S., et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function intolerant to angiotensin-converting-enzyme inhibitors: the CHARM-Alternative trial. Lancet 2003, 362:772-776.
    • (2003) Lancet , vol.362 , pp. 772-776
    • Granger, C.B.1    McMurray, J.J.2    Yusuf, S.3
  • 47
    • 71549127400 scopus 로고    scopus 로고
    • Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial
    • Konstam M.A., Neaton J.D., Dickstein K., et al. Effects of high-dose versus low-dose losartan on clinical outcomes in patients with heart failure (HEAAL study): a randomised, double-blind trial. Lancet 2009, 374:1840-1848.
    • (2009) Lancet , vol.374 , pp. 1840-1848
    • Konstam, M.A.1    Neaton, J.D.2    Dickstein, K.3
  • 48
    • 0035818884 scopus 로고    scopus 로고
    • Arandomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure
    • Valsartan Heart Failure TrialInvestigators
    • Cohn J.N., Tognoni G., Valsartan Heart Failure TrialInvestigators Arandomized trial of the angiotensin-receptor blocker valsartan in chronic heart failure. NEngl J Med 2001, 345:1667-1675.
    • (2001) NEngl J Med , vol.345 , pp. 1667-1675
    • Cohn, J.N.1    Tognoni, G.2
  • 49
    • 0041408235 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial
    • McMurray J.J., Ostergren J., Swedberg K., et al. Effects of candesartan in patients with chronic heart failure and reduced left-ventricular systolic function taking angiotensin-converting-enzyme inhibitors: the CHARM-Added trial. Lancet 2003, 362:767-771.
    • (2003) Lancet , vol.362 , pp. 767-771
    • McMurray, J.J.1    Ostergren, J.2    Swedberg, K.3
  • 50
    • 0041408234 scopus 로고    scopus 로고
    • Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial
    • Yusuf S., Pfeffer M.A., Swedberg K., et al. Effects of candesartan in patients with chronic heart failure and preserved left-ventricular ejection fraction: the CHARM-Preserved Trial. Lancet 2003, 362:777-781.
    • (2003) Lancet , vol.362 , pp. 777-781
    • Yusuf, S.1    Pfeffer, M.A.2    Swedberg, K.3
  • 51
    • 0035830414 scopus 로고    scopus 로고
    • Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure
    • Kim S., Yoshiyama M., Izumi Y., et al. Effects of combination of ACE inhibitor and angiotensin receptor blocker on cardiac remodeling, cardiac function, and survival in rat heart failure. Circulation 2001, 103:148-154.
    • (2001) Circulation , vol.103 , pp. 148-154
    • Kim, S.1    Yoshiyama, M.2    Izumi, Y.3
  • 52
    • 0033602798 scopus 로고    scopus 로고
    • Augmented short- and long-term hemodynamic and hormonal effects of an angiotensin receptor blocker added to angiotensin converting enzyme inhibitor therapy in patients with heart failure
    • Baruch L., Anand I., Cohen I.S., et al. Augmented short- and long-term hemodynamic and hormonal effects of an angiotensin receptor blocker added to angiotensin converting enzyme inhibitor therapy in patients with heart failure. Circulation 1999, 99:2658-2664.
    • (1999) Circulation , vol.99 , pp. 2658-2664
    • Baruch, L.1    Anand, I.2    Cohen, I.S.3
  • 53
    • 0033514910 scopus 로고    scopus 로고
    • Addition of angiotensin II receptor blockade to maximal angiotensin-converting enzyme inhibition improves exercise capacity in patients with severe congestive heart failure
    • Hamroff G., Katz S.D., Mancini D., et al. Addition of angiotensin II receptor blockade to maximal angiotensin-converting enzyme inhibition improves exercise capacity in patients with severe congestive heart failure. Circulation 1999, 99:990-992.
    • (1999) Circulation , vol.99 , pp. 990-992
    • Hamroff, G.1    Katz, S.D.2    Mancini, D.3
  • 54
    • 41149101190 scopus 로고    scopus 로고
    • Safety andtolerability of angiotensin-converting enzyme inhibitor versus the combination of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker in patients with left ventricular dysfunction: a systematic review and meta-analysis of randomized controlled trials
    • Lakhdar R., Al-Mallah M.H., Lanfear D.E. Safety andtolerability of angiotensin-converting enzyme inhibitor versus the combination of angiotensin-converting enzyme inhibitor and angiotensin receptor blocker in patients with left ventricular dysfunction: a systematic review and meta-analysis of randomized controlled trials. JCard Fail 2008, 14:181-188.
    • (2008) JCard Fail , vol.14 , pp. 181-188
    • Lakhdar, R.1    Al-Mallah, M.H.2    Lanfear, D.E.3
  • 55
    • 0242543981 scopus 로고    scopus 로고
    • Additive improvement of left ventricular remodeling and neurohormonal activation by aldosterone receptor blockade with eplerenone and ACE inhibition in rats with myocardial infarction
    • Fraccarollo D., Galuppo P., Hildemann S., et al. Additive improvement of left ventricular remodeling and neurohormonal activation by aldosterone receptor blockade with eplerenone and ACE inhibition in rats with myocardial infarction. JAm Coll Cardiol 2003, 42:1666-1673.
    • (2003) JAm Coll Cardiol , vol.42 , pp. 1666-1673
    • Fraccarollo, D.1    Galuppo, P.2    Hildemann, S.3
  • 56
    • 0037016007 scopus 로고    scopus 로고
    • Effects of long-term monotherapy with eplerenone, a novel aldosterone blocker, on progression of left ventricular dysfunction and remodeling in dogs with heart failure
    • Suzuki G., Morita H., Mishima T., et al. Effects of long-term monotherapy with eplerenone, a novel aldosterone blocker, on progression of left ventricular dysfunction and remodeling in dogs with heart failure. Circulation 2002, 106:2967-2972.
    • (2002) Circulation , vol.106 , pp. 2967-2972
    • Suzuki, G.1    Morita, H.2    Mishima, T.3
  • 57
    • 0038526268 scopus 로고    scopus 로고
    • Immediate administration of mineralocorticoid receptor antagonist spironolactone prevents post-infarct left ventricular remodeling associated with suppression of a marker of myocardial collagen synthesis in patients with first anterior acute myocardial infarction
    • Hayashi M., Tsutamoto T., Wada A., et al. Immediate administration of mineralocorticoid receptor antagonist spironolactone prevents post-infarct left ventricular remodeling associated with suppression of a marker of myocardial collagen synthesis in patients with first anterior acute myocardial infarction. Circulation 2003, 107:2559-2565.
    • (2003) Circulation , vol.107 , pp. 2559-2565
    • Hayashi, M.1    Tsutamoto, T.2    Wada, A.3
  • 58
    • 0034727695 scopus 로고    scopus 로고
    • Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: insights from the randomized aldactone evaluation study (RALES)
    • Zannad F., Alla F., Dousset B., et al. Limitation of excessive extracellular matrix turnover may contribute to survival benefit of spironolactone therapy in patients with congestive heart failure: insights from the randomized aldactone evaluation study (RALES). Circulation 2000, 102:2700-2706.
    • (2000) Circulation , vol.102 , pp. 2700-2706
    • Zannad, F.1    Alla, F.2    Dousset, B.3
  • 59
    • 0033517302 scopus 로고    scopus 로고
    • The effect of spironolactone on morbidity and mortality in patients with severe heart failure
    • Pitt B., Zannad F., Remme W.J., et al. The effect of spironolactone on morbidity and mortality in patients with severe heart failure. NEngl J Med 1999, 341:709-717.
    • (1999) NEngl J Med , vol.341 , pp. 709-717
    • Pitt, B.1    Zannad, F.2    Remme, W.J.3
  • 60
    • 0037417252 scopus 로고    scopus 로고
    • Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction
    • Pitt B., Remme W., Zannad F., et al. Eplerenone, a selective aldosterone blocker, in patients with left ventricular dysfunction after myocardial infarction. NEngl J Med 2003, 348:1309-1321.
    • (2003) NEngl J Med , vol.348 , pp. 1309-1321
    • Pitt, B.1    Remme, W.2    Zannad, F.3
  • 61
    • 78650399880 scopus 로고    scopus 로고
    • Eplerenone in patients with systolic heart failure and mild symptoms
    • Zannad F., McMurray J.J., Krum H., et al. Eplerenone in patients with systolic heart failure and mild symptoms. NEngl J Med 2011, 364:11-21.
    • (2011) NEngl J Med , vol.364 , pp. 11-21
    • Zannad, F.1    McMurray, J.J.2    Krum, H.3
  • 62
    • 3442886513 scopus 로고    scopus 로고
    • Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study
    • Juurlink D.N., Mamdani M.M., Lee D.S., et al. Rates of hyperkalemia after publication of the Randomized Aldactone Evaluation Study. NEngl J Med 2004, 351:543-551.
    • (2004) NEngl J Med , vol.351 , pp. 543-551
    • Juurlink, D.N.1    Mamdani, M.M.2    Lee, D.S.3
  • 63
    • 79958249630 scopus 로고    scopus 로고
    • Effects of the oral direct renin inhibitor aliskiren in patients with symptomatic heart failure
    • McMurray J.J., Pitt B., Latini R., et al. Effects of the oral direct renin inhibitor aliskiren in patients with symptomatic heart failure. Circ Heart Fail 2008, 1:17-24.
    • (2008) Circ Heart Fail , vol.1 , pp. 17-24
    • McMurray, J.J.1    Pitt, B.2    Latini, R.3
  • 64
    • 84869492851 scopus 로고    scopus 로고
    • Cardiorenal end points in a trial of aliskiren for type 2 diabetes
    • Parving H.H., Brenner B.M., McMurray J.J., et al. Cardiorenal end points in a trial of aliskiren for type 2 diabetes. NEngl J Med 2012, 367:2204-2213.
    • (2012) NEngl J Med , vol.367 , pp. 2204-2213
    • Parving, H.H.1    Brenner, B.M.2    McMurray, J.J.3
  • 65
    • 79955463305 scopus 로고    scopus 로고
    • Effect of the direct renin inhibitor aliskiren on left ventricular remodeling following myocardial infarction with systolic dysfunction
    • Solomon S.D., Shin S.H., Shah A., et al. Effect of the direct renin inhibitor aliskiren on left ventricular remodeling following myocardial infarction with systolic dysfunction. Eur Heart J 2011, 32:1227-1234.
    • (2011) Eur Heart J , vol.32 , pp. 1227-1234
    • Solomon, S.D.1    Shin, S.H.2    Shah, A.3
  • 66
    • 84875176312 scopus 로고    scopus 로고
    • Effect of aliskiren on postdischarge mortality and heart failure readmissions among patients hospitalized for heart failure: the ASTRONAUT randomized trial
    • Gheorghiade M., Bohm M., Greene S.J., et al. Effect of aliskiren on postdischarge mortality and heart failure readmissions among patients hospitalized for heart failure: the ASTRONAUT randomized trial. JAMA 2013, 309:1125-1135.
    • (2013) JAMA , vol.309 , pp. 1125-1135
    • Gheorghiade, M.1    Bohm, M.2    Greene, S.J.3
  • 67
    • 33748988737 scopus 로고    scopus 로고
    • The perindopril in elderly people with chronic heart failure (PEP-CHF) study
    • Cleland J.G., Tendera M., Adamus J., et al. The perindopril in elderly people with chronic heart failure (PEP-CHF) study. Eur Heart J 2006, 27:2338-2345.
    • (2006) Eur Heart J , vol.27 , pp. 2338-2345
    • Cleland, J.G.1    Tendera, M.2    Adamus, J.3
  • 68
    • 57349142933 scopus 로고    scopus 로고
    • Irbesartan in patients with heart failure and preserved ejection fraction
    • Massie B.M., Carson P.E., McMurray J.J., et al. Irbesartan in patients with heart failure and preserved ejection fraction. NEngl J Med 2008, 359:2456-2467.
    • (2008) NEngl J Med , vol.359 , pp. 2456-2467
    • Massie, B.M.1    Carson, P.E.2    McMurray, J.J.3
  • 69
    • 84874367056 scopus 로고    scopus 로고
    • Effect of spironolactone on diastolic function and exercise capacity in patients with heart failure with preserved ejection fraction: the Aldo-DHF randomized controlled trial
    • Edelmann F., Wachter R., Schmidt A.G., et al. Effect of spironolactone on diastolic function and exercise capacity in patients with heart failure with preserved ejection fraction: the Aldo-DHF randomized controlled trial. JAMA 2013, 309:781-791.
    • (2013) JAMA , vol.309 , pp. 781-791
    • Edelmann, F.1    Wachter, R.2    Schmidt, A.G.3


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