How one TSH receptor antibody induces thyrocyte proliferation while another induces apoptosis

Journal of Autoimmunity

Volumn 47, Issue , 2013, Pages 17-24

  Morshed, Syed A ^a   Ma, Risheng ^a   Latif, Rauf ^a   Davies, Terry F ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

Author keywords

Antibodies; Apoptosis; Proliferation; ROS signaling; Thyrocyte; TSH receptor

Indexed keywords

ANTIMYCIN A1; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; IMMUNOGLOBULIN G; ISOBUTYLMETHYLXANTHINE; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; ROTENONE; S6 KINASE; THYROTROPIN; THYROTROPIN RECEPTOR ANTIBODY;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; CELL STRESS; CELL SURVIVAL; CONTROLLED STUDY; ENDOPLASMIC RETICULUM STRESS; EX VIVO STUDY; FLUORESCENCE MICROSCOPY; FLUOROMETRY; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; MITOCHONDRIAL MEMBRANE; MOLECULAR IMAGING; NONHUMAN; PRIORITY JOURNAL; RAT; SIGNAL TRANSDUCTION; THYROID CELL; THYROTROPIN BLOOD LEVEL;

ANTIBODIES; APOPTOSIS; PROLIFERATION; ROS-SIGNALING; THYROCYTE; TSH RECEPTOR;

ANIMALS; APOPTOSIS; CELL PROLIFERATION; CELL SURVIVAL; CELLS, CULTURED; CREB-BINDING PROTEIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GRAVES DISEASE; HUMANS; IMMUNOGLOBULINS, THYROID-STIMULATING; MITOCHONDRIA; PROTO-ONCOGENE PROTEINS C-AKT; RATS; REACTIVE OXYGEN SPECIES; RECEPTORS, THYROTROPIN; RIBOSOMAL PROTEIN S6 KINASES, 70-KDA; SIGNAL TRANSDUCTION; THYROID GLAND; TOR SERINE-THREONINE KINASES;

EID: 84888206132     PISSN: 08968411     EISSN: 10959157     Source Type: Journal    
DOI: 10.1016/j.jaut.2013.07.009     Document Type: Article

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