β-actin knock-out mouse embryonic fibroblasts show increased expression of LIM-, CH-, EFh-domain containing proteins with predicted common upstream regulators

Cytoskeleton

Volumn 70, Issue 11, 2013, Pages 766-774

  Ampe, Christophe ^a   Libbrecht, Jelle ^a   Van Troys, Marleen ^a  

^a GHENT UNIVERSITY   (Belgium)

Author keywords

Actin cytoskeleton; CH domain; LIM domain; Stress fiber; Transcription factor

Indexed keywords

ACTIN BINDING PROTEIN; BETA ACTIN; CALPONIN; CALPONIN HOMOLOGY; LIM PROTEIN; PROTEOME; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; DATA MINING; EMBRYO; FIBROBLAST; FOCAL ADHESION; GENE OVEREXPRESSION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN MOTIF; STRESS FIBER;

ACTIN CYTOSKELETON; CH-DOMAIN; LIM-DOMAIN; STRESS FIBER; TRANSCRIPTION FACTOR;

ACTIN CYTOSKELETON; ACTINS; ANIMALS; CYTOSKELETAL PROTEINS; EMBRYO, MAMMALIAN; FIBROBLASTS; LIM DOMAIN PROTEINS; MICE; MICE, KNOCKOUT; PROTEIN STRUCTURE, TERTIARY; PROTEOME; PROTEOMICS; REGULATORY SEQUENCES, NUCLEIC ACID; SOFTWARE; STRESS FIBERS;

EID: 84888205592     PISSN: 19493584     EISSN: 19493592     Source Type: Journal    
DOI: 10.1002/cm.21147     Document Type: Article

References (23)

1. Ashburner M, Ball CA, Blake JA, Botstein D, Butler H, Cherry JM, Davis AP, Dolinski K, Dwight SS, Eppig JT, Harris MA, Hill DP, Issel-Tarver L, Kasarskis A, Lewis S, Matese JC, Richardson JE, Ringwald M, Rubin GM, Sherlock G. 2000. Gene ontology: Tool for the unification of biology. The gene ontology consortium. Nat Genet 25:25-29.
2. Boiko AD, Porteous S, Razorenova OV, Krivokrysenko VI, Williams BR, Gudkov AV. 2006. A systematic search for downstream mediators of tumor suppressor function of p53 reveals a major role of BTG2 in suppression of Ras-induced transformation. Genes Dev 20:236-252.
3. Brandt DT, Xu J, Steinbeisser H, Grosse R. 2009. Regulation of myocardin-related transcriptional coactivators through cofactor interactions in differentiation and cancer. Cell Cycle 8:2523-2527.
4. Bunnell TM, Burbach BJ, Shimizu Y, Ervasti JM. 2011. β-Actin specifically controls cell growth, migration, and the G-actin pool. Mol Biol Cell 22:4047-4058.
5. Chhabra ES, Higgs HN. 2007. The many faces of actin: matching assembly factors with cellular structures. Nat Cell Biol 9:1110-1121.
6. Hirata H, Tatsumi, H, Sokabe, M. 2008. Zyxin emerges as a key player in the mechanotransduction at cell adhesive structures. Commun Integr Biol 1:192-195.
7. Huang DW, Sherman BT, Lempicki RA. 2009a. Systematic and integrative analysis of large gene lists using DAVID Bioinformatics Resources. Nat Protoc 4:44-57.
8. Huang DW, Sherman BT, Lempicki RA. 2009b. Bioinformatics enrichment tools: paths toward the comprehensive functional analysis of large gene lists. Nucleic Acids Res 37:1-13.
9. Järvinen PM, Laiho M. 2011. LIM-domain proteins in transforming growth factor β-induced epithelial-to-mesenchymal transition and myofibroblast differentiation. Cell Signal 24:819-825.
10. Lasorella A, Noseda M, Beyna M, Yokota Y, Iavarone A. 2000. Id2 is a retinoblastoma protein target and mediates signalling by Myc oncoproteins. Nature 407:592-598.
11. Maddox AS, Azoury J, Dumont J. 2012. Polar body cytokinesis. Cytoskeleton (Hoboken). 69:855-868.
12. Miralles F, Posern G, Zaromytidou A.-I, Treisman R. 2003. Actin dynamics control SRF activity by regulation of its coactivator MAL. Cell 113, 329-342.
13. Parmacek MS. 2007. Myocardin-related transcription factors: critical coactivators regulating cardiovascular development and adaptation. Circ Res 100:633-644.
14. Ridley AJ. 2011. Life at the leading edge. Cell 145:1012-1022.
15. Schiller HB, Friedel CC, Boulegue C, Fässler R. 2011. Quantitative proteomics of the integrin adhesome show a myosin II-dependent recruitment of LIM domain proteins. EMBO Rep 12:259-266.
16. Shmerling D, Danzer CP, Mao X, Boisclair J, Haffner M, Lemaistre M, Schuler V, Kaeslin E, Korn R, Bürki K, Ledermann B, Kinzel B, Müller M. 2005. Strong and ubiquitous expression of transgenes targeted into the β-actin locus by Cre/lox cassette replacement. Genesis 42:229-235.
17. Sjöblom B, Ylänne J, Djinović-Carugo K. 2008. Novel structural insights into F-actin-binding and novel functions of calponin homology domains. Curr Opin Struct Biol 18:702-708.
18. Tondeleir D, Vandamme D, Vandekerckhove J, Ampe C, Lambrechts A. 2009. Actin isoform expression patterns during mammalian development and in pathology: insights from mouse models. Cell Motil Cytoskeleton 66:798-815.
19. Tondeleir D, Lambrechts A, Müller M, Jonckheere V, Doll T, Vandamme D, Bakkali K, Waterschoot D, Lemaistre M, Debeir O, Decaestecker C, Hinz B, Staes A, Timmerman E, Colaert N, Gevaert K, Vandekerckhove J, Ampe C. 2012. Cells lacking β-actin are genetically reprogrammed and maintain conditional migratory capacity. Mol Cell Proteomics 11:255-271.
20. Vallenius T. 2013. Actin stress fibre subtypes in mesenchymal-migrating cells. Open Biol 3:130001.
21. Wehrle-Haller B. 2012. Assembly and disassembly of cell matrix adhesions. Curr Opin Cell Biol 24:569-581.
22. Yáñez M, Gil-Longo J, Campos-Toimil M. 2012. Calcium binding proteins. Adv Exp Med Biol 740:461-82.
23. Zaidel-Bar R, Itzkovitz S, Ma'ayan A, Iyengar R, Geiger B. 2007. Functional atlas of the integrin adhesome. Nat Cell Biol 9:858-67.