MG53's new identity

Skeletal Muscle

Volumn 3, Issue 1, 2013, Pages

  Levy, Jennifer R ^a   Campbell, Kevin P ^a   Glass, David J ^b  

^a UNIVERSITY OF IOWA   (United States)

^b NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH   (United States)

Author keywords

E3 ubiquitin ligase; Insulin receptor; Insulin signaling; Metabolic syndrome; MG53; Mitsugumin 53; TRIM72

Indexed keywords

EID: 84888205280     PISSN: None     EISSN: 20445040     Source Type: Journal    
DOI: 10.1186/2044-5040-3-25     Document Type: Note

References (18)

1. Eckel RH, Grundy SM, Zimmet PZ. The metabolic syndrome. Lancet 2005, 365(9468):1415-1428. 10.1016/S0140-6736(05)66378-7, 15836891.
2. DeFronzo RA, Jacot E, Jequier E, Maeder E, Wahren J, Felber JP. The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization. Diabetes 1981, 30(12):1000-1007. 10.2337/diab.30.12.1000, 7030826.
3. Shulman GI, Rothman DL, Jue T, Stein P, DeFronzo RA, Shulman RG. Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy. New Eng J Med 1990, 322(4):223-228. 10.1056/NEJM199001253220403, 2403659.
4. Weisleder N, Takeshima H, Ma J. Immuno-proteomic approach to excitation-contraction coupling in skeletal and cardiac muscle: molecular insights revealed by the mitsugumins. Cell calcium 2008, 43(1):1-8. 10.1016/j.ceca.2007.10.006, 3059838, 18061662.
5. Cai C, Masumiya H, Weisleder N, Matsuda N, Nishi M, Hwang M, Ko JK, Lin P, Thornton A, Zhao X, Pan Z, Komazaki S, Brotto M, Takeshima H, Ma J. MG53 nucleates assembly of cell membrane repair machinery. Nat Cell Biol 2009, 11(1):56-64. 10.1038/ncb1812, 2990407, 19043407.
6. Song R, Peng W, Zhang Y, Lv F, Wu HK, Guo J, Cao Y, Pi Y, Zhang X, Jin L, Zhang M, Jiang P, Liu F, Meng S, Zhang X, Jiang P, Cao CM, Xiao RP. Central role of E3 ubiquitin ligase MG53 in insulin resistance and metabolic disorders. Nature 2013, 494(7437):375-379. 10.1038/nature11834, 23354051.
7. Cai C, Masumiya H, Weisleder N, Pan Z, Nishi M, Komazaki S, Takeshima H, Ma J. MG53 regulates membrane budding and exocytosis in muscle cells. J Biol Chem 2009, 284(5):3314-3322. 2631961, 19029292.
8. Waddell LB, Lemckert FA, Zheng XF, Tran J, Evesson FJ, Hawkes JM, Lek A, Street NE, Lin P, Clarke NF, Landstrom AP, Ackerman MJ, Weisleder N, Ma J, North KN, Cooper ST. Dysferlin, annexin A1, and mitsugumin 53 are upregulated in muscular dystrophy and localize to longitudinal tubules of the T-system with stretch. J Neuropathol Exper Neurol 2011, 70(4):302-313.
9. Glass DJ. PI3 kinase regulation of skeletal muscle hypertrophy and atrophy. Curr Top Microbiol Immunol 2010, 346:267-278. 10.1007/82_2010_78, 20593312.
10. Lee CS, Yi JS, Jung SY, Kim BW, Lee NR, Choo HJ, Jang SY, Han J, Chi SG, Park M, Lee JH, Ko KG. TRIM72 negatively regulates myogenesis via targeting insulin receptor substrate-1. Cell Death Differ 2010, 17(8):1254-1265. 10.1038/cdd.2010.1, 20139895.
11. Howard AC, McNeil AK, Xiong F, Xiong WC, McNeil PL. A novel cellular defect in diabetes: membrane repair failure. Diabetes 2011, 60(11):3034-3043. 10.2337/db11-0851, 3198060, 21940783.
12. Liu L, Brown D, McKee M, Lebrasseur NK, Yang D, Albrecht KH, Ravid K, Pilch PF. Deletion of Cavin/PTRF causes global loss of caveolae, dyslipidemia, and glucose intolerance. Cell metabolism 2008, 8(4):310-317. 10.1016/j.cmet.2008.07.008, 2581738, 18840361.
13. Capozza F, Combs TP, Cohen AW, Cho YR, Park SY, Schubert W, Williams TM, Brasaemle DL, Jelicks LA, Scherer PE, Kim JK, Lisanti MP. Caveolin-3 knockout mice show increased adiposity and whole body insulin resistance, with ligand-induced insulin receptor instability in skeletal muscle. Am J Physiol Cell Physiol 2005, 288(6):C1317-C1331. 10.1152/ajpcell.00489.2004, 15689413.
14. Lee KJ, Park CS, Woo JS, Kim do H, Ma J, Lee EH. Mitsugumin 53 attenuates the activity of sarcoplasmic reticulum Ca2+-ATPase 1a (SERCA1a) in skeletal muscle. Biochem Biophys Res Comm 2012, 428(3):383-388. 10.1016/j.bbrc.2012.10.063, 23103543.
15. Bruning JC, Michael MD, Winnay JN, Hayashi T, Horsch D, Accili D, Goodyear LJ, Kahn CR. A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance. Molecular cell 1998, 2(5):559-569. 10.1016/S1097-2765(00)80155-0, 9844629.
16. Kim JK, Michael MD, Previs SF, Peroni OD, Mauvais-Jarvis F, Neschen S, Kahn BB, Kahn CR, Shulman GI. Redistribution of substrates to adipose tissue promotes obesity in mice with selective insulin resistance in muscle. J Clin Invest 2000, 105(12):1791-1797. 10.1172/JCI8305, 378504, 10862794.
17. Yi JS, Park JS, Ham YM, Nguyen N, Lee NR, Hong J, Kim BW, Lee H, Lee CS, Jeong BC, Song HK, Cho H, Kim YK, Lee JS, Park KS, Shin H, Choi I, Lee SH, Park WJ, Park SY, Choi CS, Lin P, Karunasiri M, Tan T, Duann P, Zhu H, Ma J, Ko YG. MG53-induced IRS-1 ubiquitination negatively regulates skeletal myogenesis and insulin signalling. Nat Comm 2013, 4:2354.
18. Weisleder N, Takizawa N, Lin P, Wang X, Cao C, Zhang Y, Tan T, Ferrante C, Zhu H, Chen PJ, Yan R, Sterling M, Zhao X, Hwang M, Takeshima M, Cai C, Cheng H, Takeshima H, Xiao RP, Ma J. Recombinant MG53 protein modulates therapeutic cell membrane repair in treatment of muscular dystrophy. Sci Trans Med 2012, 4(139):139-185.