Zinc ferrite nanoparticles activate IL-1b, NFKB1, CCL21 and NOS2 signaling to induce mitochondrial dependent intrinsic apoptotic pathway in WISH cells

Toxicology and Applied Pharmacology

Volumn 273, Issue 2, 2013, Pages 289-297

  Saquib, Quaiser ^a   Al Khedhairy, Abdulaziz A ^a   Ahmad, Javed ^a   Siddiqui, Maqsood A ^a   Dwivedi, Sourabh ^a   Khan, Shams T ^a   Musarrat, Javed ^a,b  

^a KING SAUD UNIVERSITY   (Saudi Arabia)

^b ALIGARH MUSLIM UNIVERSITY   (India)

Author keywords

Apoptosis; Cytotoxicity; DNA damage; Nanoparticles; Oxidative stress; Zinc ferrite

Indexed keywords

CASPASE 3; CELL PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; NANOPARTICLE; NF KAPPA B1 PROTEIN; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; SECONDARY LYMPHOID TISSUE CHEMOKINE; UNCLASSIFIED DRUG; ZINC FERRITE NANOPARTICLE;

AMNION CELL; APOPTOSIS; ARTICLE; CELL ASSAY; CELL CYCLE; CELL MEMBRANE; CELL PROLIFERATION; CELL VIABILITY; CONTROLLED STUDY; CYTOPLASM; CYTOTOXICITY; DNA DAMAGE; DNA REPAIR; DNA STRAND BREAKAGE; DOWN REGULATION; ECOTOXICITY; GENE; GENE ACTIVATION; GENETIC DAMAGE; GENOTOXICITY; HUMAN; HUMAN CELL; INFLAMMATION; MITOCHONDRIAL MEMBRANE POTENTIAL; MITOCHONDRIAL TOXICITY; NFKB1 GENE; OXIDATIVE STRESS; PROTEIN FOLDING; SIGNAL TRANSDUCTION; UPREGULATION;

APOPTOSIS; CYTOTOXICITY; DNA DAMAGE; NANOPARTICLES; OXIDATIVE STRESS; ZINC FERRITE;

AMNION; APOPTOSIS; CHEMOKINE CCL21; DOSE-RESPONSE RELATIONSHIP, DRUG; EPITHELIAL CELLS; FERRIC COMPOUNDS; HUMANS; INTERLEUKIN-1BETA; METAL NANOPARTICLES; MITOCHONDRIA; NF-KAPPA B P50 SUBUNIT; NITRIC OXIDE SYNTHASE TYPE II; PARTICLE SIZE; REACTIVE OXYGEN SPECIES; ZINC;

EID: 84888202221     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2013.09.001     Document Type: Article

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