Performance improvement of cephalosporin C fermentation by Acremonium chrysogenum with DO-Stat based strategy of co-feeding soybean oil and glucose

Process Biochemistry

Volumn 48, Issue 12, 2013, Pages 1822-1830

  Luo, Hongzhen ^a   Zhang, Jingshu ^b   Yuan, Guoqiang ^b   Zhao, Yanli ^b   Liu, Han ^a   He, Zhenni ^a   Shi, Zhongping ^a  

^a JIANGNAN UNIVERSITY   (China)

^b Shijiazhuang   (China)

Author keywords

Cephalosporin C; Co substrates feeding; DO Stat; Fermentation

Indexed keywords

CEPHALOSPORIN C; COSUBSTRATES; DO-STAT; FEEDING STRATEGIES; FERMENTATION PERFORMANCE; FERMENTATION PRODUCTS; OXYGEN TRANSFER RATE; RAW MATERIALS COSTS;

ANTIBIOTICS; FEEDING; GLUCOSE; PRODUCTIVITY; SOYBEAN OIL;

FERMENTATION;

ACREMONIUM CHRYSOGENUM; GLYCINE MAX;

EID: 84888197863     PISSN: 13595113     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.procbio.2013.09.021     Document Type: Article

References (28)

1. E.K. Schmitt, B. Hoff, and U. Kuck Regulation of cephalosporin biosynthesis Adv Biochem Eng Biotechnol 88 2004 1 43
2. J. Li, Y. Yang, J. Chu, M. Huang, L. Li, and X. Zhang Quantitative metabolic flux analysis revealed uneconomical utilization of ATP and NADPH in Acremonium chrysogenum fed with soybean oil Bioprocess Biosyst Eng 33 2010 1119 1129
3. Y. Yang, J. Xia, J. Li, J. Chu, L. Li, and Y. Wang A novel impeller configuration to improve fungal physiology performance and energy conservation for cephalosporin C production J Biotechnol 161 2012 250 256
4. B. Hamad The antibiotics market Nat Rev Drug Discov 9 2010 675 676
5. IMS The global use of medicines: outlook through 2016 2012 IMS Institute for Healthcare Informatics
6. C. Pan, S. Speth, E. McKillip, and C. Nash III Methyl oleate-based fermentation medium for cephalosporin C production Dev Ind Microbiol 23 1982 315 324
7. L. Karaffa, E. Sandor, J. Kozma, C.P. Kubicek, and A. Szentirmai The role of the alternative respiratory pathway in the stimulation of cephalosporin C formation by soybean oil in Acremonium chrysogenum Appl Microbiol Biotechnol 51 1999 633 638
8. J.C. Kim, S.W. Kang, J.S. Lim, Y.S. Song, and S.W. Kim Stimulation of cephalosporin C production by Acremonium chrysogenum M35 with fatty acids J Microbiol Biotechnol 16 2006 1120 1124
9. C.J. Behmer, and A.L. Demain Further studies on carbon catabolite regulation of β-lactam antibiotic synthesis in Cephalosporium acremonium Curr Microbiol 8 1983 107 114
10. G. Seidel, C. Tollnick, M. Beyer, and K. Schugerl Process engineering aspects of the production of cephalosporin C by Acremonium chrysogenum. Part II. Cultivation in diluted and enriched complex media Process Biochem 38 2002 241 248
11. F.M. Arshad, and A.A.A. Hameed Crude oil, palm oil stock and prices: how they link Rev Econom Finan 3 2013 48 57
12. H.Y. Shin, J.Y. Lee, H.S. Choi, J.H. Lee, and S.W. Kim Production of cephalosporin C using crude glycerol in fed-batch culture of Acremonium chrysogenum M35 J Microbiol 49 2011 753 758
13. G. Seidel, C. Tollnick, M. Beyer, Y. Fahimi, and K. Schugerl Process engineering aspects of the production of cephalosporin C by Acremonium chrysogenum. Part I. Application of complex media Process Biochem 38 2002 229 239
14. A.A. Brakhage, P. Sprote, Q. Al-Abdallah, A. Gehrke, H. Plattner, and A. Tuncher Regulation of penicillin biosynthesis in filamentous fungi Adv Biochem Eng Biotechnol 88 2004 45 90
15. W.A. Lotfy The utilization of beet molasses as a novel carbon source for cephalosporin C production by Acremonium chrysogenum: optimization of process parameters through statistical experimental designs Bioresour Technol 98 2007 3491 3498
16. H.Y. Shin, J.Y. Lee, Y.R. Jung, and S.W. Kim Stimulation of cephalosporin C production in Acremonium chrysogenum M35 by glycerol Bioresour Technol 101 2010 4549 4553
17. P. Hilgendorf, V. Heiser, H. Diekmann, and M. Thoma Constant dissolved oxygen concentrations in cephalosporin C fermentation: applicability of different controllers and effect on fermentation parameters Appl Microbiol Biotechnol 27 1987 247 251
18. P. Mishra, P. Srivastava, and S. Kundu A comparative evaluation of oxygen mass transfer and broth viscosity using Cephalosporin-C production as a case strategy World J Microbiol Biotechnol 21 2005 525 530
19. C. Tollnick, G. Seidel, M. Beyer, and K. Schugerl Investigations of the production of cephalosporin C by Acremonium chrysogenum Adv Biochem Eng Biotechnol 86 2004 1 45
20. W. Zhou, K. Holzhauerrieger, M. Dors, and K. Schugerl Influence of dissolved-oxygen concentration on the biosynthesis of cephalosporin-C Enzyme Microb Technol 14 1992 848 854
21. R.P. Elander Industrial production of β-lactam antibiotics Appl Microbiol Biotechnol 61 2003 385 392
22. S. Duan, G. Yuan, Y. Zhao, H. Li, W. Ni, and M. Sang Enhanced cephalosporin C production with a combinational ammonium sulfate and DO-Stat based soybean oil feeding strategy Biochem Eng J 61 2012 1 10
23. S. Chiang Strain improvement for fermentation and biocatalysis processes by genetic engineering technology J Ind Microbiol Biotechnol 31 2004 99 108
24. J.H. Kim, J.S. Lim, and S.W. Kim The improvement of cephalosporin C production by fed-batch culture of Cephalosporium acremonium M25 using rice oil Biotechnol Bioprocess Eng 9 2004 459 464
25. C.Y. Li, C.Y. Cheng, and T.L. Chen Fed-batch production of lipase by Acinetobacter radioresistens using Tween 80 as the carbon source Biochem Eng J 19 2004 25 31
26. H. Jin, Z. Zheng, M. Gao, Z. Duan, Z. Shi, and Z. Wang Effective induction of phytase in Pichia pastoris fed-batch culture using an ANN pattern recognition model-based on-line adaptive control strategy Biochem Eng J 37 2007 26 33
27. La) using the dynamic "gas out-gas in" method: analysis of errors caused by dissolved-oxygen probes Biotechnol Bioeng 46 1995 388 392
28. G. Ozcengiz, and A.L. Demain Recent advances in the biosynthesis of penicillins, cephalosporins and clavams and its regulation Biotechnol Adv 31 2013 287 311