Cardiotonic pill attenuates white matter and hippocampal damage via inhibiting microglial activation and downregulating ERK and p38 MAPK signaling in chronic cerebral hypoperfused rat

BMC Complementary and Alternative Medicine

Volumn 13, Issue , 2013, Pages

  Lee, Ki M ^a   Bang, Ji H ^a   Han, Jung Soo ^b   Kim, Bu Y ^a   Lee, In S ^a   Kang, Hyung W ^c   Jeon, Won K ^a  

^a Korea Institute of Oriental Medicine (KIOM)   (South Korea)

^b Konkuk University   (South Korea)

^c Wonkwang University   (South Korea)

Author keywords

Cardiotonic pill; Hippocampus; Inflammation; Microglia; Permanent bilateral common carotid artery occlusion; White matter

Indexed keywords

CARDIOTONIC AGENT; CARDIOTONIC PILL; CYCLOOXYGENASE 2; INTERLEUKIN 1BETA; INTERLEUKIN 6; MITOGEN ACTIVATED PROTEIN KINASE; MYELIN BASIC PROTEIN; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN DAMAGE; BRAIN PERFUSION; CAROTID ARTERY OBSTRUCTION; CHRONIC CEREBRAL HYPOPERFUSION; COMMON CAROTID ARTERY; HIPPOCAMPUS; MALE; MICROGLIA; NONHUMAN; PILL; PROTEIN EXPRESSION; RAT; WHITE MATTER; WISTAR RAT;

ANALYSIS OF VARIANCE; ANIMALS; CARDIOTONIC AGENTS; CAROTID STENOSIS; CYCLOOXYGENASE 2; DIPTEROCARPACEAE; DRUGS, CHINESE HERBAL; HIPPOCAMPUS; INTERLEUKIN-1BETA; INTERLEUKIN-6; MALE; MAP KINASE SIGNALING SYSTEM; MICROGLIA; MITOGEN-ACTIVATED PROTEIN KINASES; MYELIN BASIC PROTEIN; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PANAX NOTOGINSENG; PHOSPHORYLATION; RATS; RATS, WISTAR; SALVIA MILTIORRHIZA;

EID: 84888186493     PISSN: None     EISSN: 14726882     Source Type: Journal    
DOI: 10.1186/1472-6882-13-334     Document Type: Article

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