Intensity of chronic cerebral hypoperfusion determines white/gray matter injury and cognitive/motor dysfunction in mice

Journal of Neuroscience Research

Volumn 87, Issue 5, 2009, Pages 1270-1281

  Miki, Kazunori ^a   Ishibashi, Satoru ^a,b   Sun, Liyuan ^a   Xu, Haiyan ^a   Ohashi, Wataru ^a   Kuroiwa, Toshihiko ^c,d   Mizusawa, Hidehiro ^a  

^a TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^b NATIONAL INSTITUTE OF NEUROLOGICAL DISORDERS AND STROKE   (United States)

^c Namegata District General Hospital   (Japan)

^d TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

Author keywords

Cerebral blood flow; Cognitive impairment; Ischemia; Mouse; White matter

Indexed keywords

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN BLOOD FLOW; BRAIN INJURY; BRAIN PERFUSION; CAROTID ARTERY OBSTRUCTION; CELL LOSS; COGNITIVE DEFECT; CONTROLLED STUDY; DISEASE SEVERITY; GRAY MATTER; HISTOPATHOLOGY; IMMUNOHISTOCHEMISTRY; LOCOMOTION; MALE; MAZE TEST; MOTOR ACTIVITY; MOTOR DYSFUNCTION; MOUSE; NONHUMAN; OPEN FIELD TEST; PRIORITY JOURNAL; PYRAMIDAL NERVE CELL; REFERENCE MEMORY; ROTAROD TEST; WHITE MATTER;

ANALYSIS OF VARIANCE; ANIMALS; ANXIETY; BRAIN ISCHEMIA; CAROTID STENOSIS; CEREBROVASCULAR CIRCULATION; CEREBRUM; COGNITION DISORDERS; DEMENTIA, VASCULAR; DISEASE MODELS, ANIMAL; IMMUNOHISTOCHEMISTRY; LASER-DOPPLER FLOWMETRY; MALE; MAZE LEARNING; MEMORY; MICE; MICE, INBRED C57BL; MOTOR ACTIVITY; ROTAROD PERFORMANCE TEST; SPACE PERCEPTION;

EID: 65949093271     PISSN: 03604012     EISSN: 10974547     Source Type: Journal    
DOI: 10.1002/jnr.21925     Document Type: Article

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