Studies on the synthetic and structural aspects of benzosuberones bearing 2, 4-thiazolidenone moiety as potential anti-cancer agents

European Journal of Medicinal Chemistry

Volumn 71, Issue , 2014, Pages 91-97

  Nagarapu, Lingaiah ^a   Yadagiri, Bandi ^a   Bantu, Rajashaker ^a   Kumar, C Ganesh ^a   Pombala, Sujitha ^a   Nanubolu, Jagadesh ^a  

^a INDIAN INSTITUTE OF CHEMICAL TECHNOLOGY   (India)

Author keywords

2,4 Thiazolidenone; Benzosuberone; Cytotoxicity; Knoevenagel condensation; Vilsmeier Haack Arnold reaction

Indexed keywords

3 (2 OXO 2 4 TOLYLETHYL)THIAZOLIDINE 2,4 DIONE; 3 (2 OXO 2 PHENYLETHYL)THIAZOLIDINE 2,4 DIONE; 3 [2 (4 BROMOPHENYL) 2 OXOETHYL] 5 [(9 CHLORO 2,3 DIMETHYL 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE]THIAZOLIDINE 2,4 DIONE; 3 [2 (4 BROMOPHENYL) 2 OXOETHYL] 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE]THIAZOLIDINE 2,4 DIONE; 3 [2 (4 BROMOPHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 3 [2 (4 CHLOROPHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 3 [2 (4 METHOXYPHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 2,3 DIMETHYL 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 (2 OXO 2 PHENYLETHYL)THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 2,3 DIMETHYL 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 [2 (4 CHLOROPHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 2,3 DIMETHYL 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 [2 (4 METHOXYPHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 2,3 DIMETHYL 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 [2 OXO 2 (P TOLYL)ETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 2,3 DIMETHYL 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE]THIAZO LIDINE 2,4 DIONE; 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL) METHYLENE]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 (2 OXO 2 PHENYL ETHYL)THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 [2 (4 CHLOROPHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 [2 (4 METHOXYPHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 [2 OXO 2 (P TOLYL)ETHYL]THIAZOLIDINE 2,4 DIONE; ANTINEOPLASTIC AGENT; DOXORUBICIN; THIAZOLIDINE DERIVATIVE; UNCLASSIFIED DRUG; 5 CHLORO 2,3 DIMETHYL 8,9 DIHYDRO 7H BENZOCYCLOHEPTENE 6 CARBALDEHYDE(; 5 CHLORO 8,9 DIHYDRO 7H BENZOCYCLOHEPTENE 6 CARBALDEHYDE; 5 [(9 CHLORO 2,3 DIMETHYL 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE) 3 [2 (4 CHLOROPHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 2,3 DIMETHYL 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE) 3 [2 (4 METHOXYPHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 2,3 DIMETHYL 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE) 3 [2 OXO 2 (4 TOLYL)THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 2,3 DIMETHYL 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 (2 OXO 2 PHENYLETHYL)THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 [2 (4 CHLOROHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 [2 (4METHOXYPHENYL) 2 OXOETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE] 3 [2 OXO 2 (4 TOLYL)ETHYL]THIAZOLIDINE 2,4 DIONE; 5 [(9 CHLORO 6,7 DIHYDRO 5H BENZO[7]ANNULEN 8 YL)METHYLENE]THIAZOLIDINE 2,4 DIONE; ACETIC ACID; CYTOTOXIC AGENT;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CELL VIABILITY; DRUG CYTOTOXICITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; KNOEVENAGEL CONDENSATION; X RAY CRYSTALLOGRAPHY; A549 CELL LINE; CANCER CELL LINE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENCY; DRUG SCREENING; HELA CELL LINE; IC50; LIQUID; MCF 7 CELL LINE;

2, 4-THIAZOLIDENONE; BENZOSUBERONE; CYTOTOXICITY; KNOEVENAGEL CONDENSATION; VILSMEIER HAACK ARNOLD REACTION;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CYCLOHEPTANES; HEK293 CELLS; HELA CELLS; HUMANS; MODELS, MOLECULAR; NEOPLASMS; THIAZOLES;

EID: 84888139352     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2013.10.078     Document Type: Article

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