Avoidable antibiotic exposure for uncomplicated skin and soft tissue infections in the ambulatory care setting

American Journal of Medicine

Volumn 126, Issue 12, 2013, Pages 1099-1106

  Hurley, Hermione J ^a,b   Knepper, Bryan C ^a   Price, Connie S ^a,b   Mehler, Philip S ^a,b   Burman, William J ^a,b   Jenkins, Timothy C ^a,b  

^a DENVER HEALTH MEDICAL CENTER   (United States)

^b UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

Author keywords

Abscess; Antimicrobial stewardship; Cellulitis; Skin and soft tissue infection; Uncomplicated skin and soft tissue infection

Indexed keywords

AMOXICILLIN PLUS CLAVULANIC ACID; CEFALEXIN; CLINDAMYCIN; COTRIMOXAZOLE; DICLOXACILLIN; DOXYCYCLINE; PENICILLIN DERIVATIVE;

ADOLESCENT; ADULT; AGED; AMBULATORY CARE; ANTIBIOTIC THERAPY; ARTICLE; CELLULITIS; CHILD; COMBINATION CHEMOTHERAPY; CONTROLLED STUDY; DRUG USE; FEMALE; HUMAN; INFANT; MAJOR CLINICAL STUDY; MALE; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; PRACTICE GUIDELINE; PRESCHOOL CHILD; PRESCRIPTION; PRIORITY JOURNAL; SCHOOL CHILD; SKIN ABSCESS; WOUND INFECTION;

ABSCESS; ANTIMICROBIAL STEWARDSHIP; CELLULITIS; SKIN AND SOFT TISSUE INFECTION; UNCOMPLICATED SKIN AND SOFT TISSUE INFECTION;

ADOLESCENT; ADULT; AGED; AGED, 80 AND OVER; AMBULATORY CARE; ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; COHORT STUDIES; HUMANS; INFANT; MIDDLE AGED; RETROSPECTIVE STUDIES; SKIN DISEASES, BACTERIAL; SOFT TISSUE INFECTIONS; YOUNG ADULT;

EID: 84888085532     PISSN: 00029343     EISSN: 15557162     Source Type: Journal    
DOI: 10.1016/j.amjmed.2013.08.016     Document Type: Article

References (26)

1. L.A. Hicks, Y.W. Chien, and T.H. Taylor Jr. Outpatient antibiotic prescribing and nonsusceptible Streptococcus pneumoniae in the United States, 1996-2003 Clin Infect Dis 53 2011 631 639
2. L. Johnson, A. Sabel, and W.J. Burman Emergence of fluoroquinolone resistance in outpatient urinary Escherichia coli isolates Am J Med 121 2008 876 884
3. L. Sun, E.Y. Klein, and R. Laxminarayan Seasonality and temporal correlation between community antibiotic use and resistance in the United States Clin Infect Dis 55 2012 687 694
4. N. Shehab, P.R. Patel, and A. Srinivasan Emergency department visits for antibiotic-associated adverse events Clin Infect Dis 47 2008 735 743
5. L. Benson, X. Song, and J. Campos Changing epidemiology of Clostridium difficile-associated disease in children Infect Control Hosp Epidemiol 28 2007 1233 1235
6. A.L. Hersh, H.F. Chambers, and J.H. Maselli National trends in ambulatory visits and antibiotic prescribing for skin and soft-tissue infections Arch Intern Med 168 2008 1585 1591
7. D.J. Pallin, D.J. Egan, and A.J. Pelletier Increased US emergency department visits for skin and soft tissue infections, and changes in antibiotic choices, during the emergence of community-associated methicillin-resistant Staphylococcus aureus Ann Emerg Med 51 2008 291 298
8. T.C. Jenkins, A.L. Sabel, and E.E. Sarcone Skin and soft-tissue infections requiring hospitalization at an academic medical center: opportunities for antimicrobial stewardship Clin Infect Dis 51 2010 895 903
9. T.C. Jenkins, B.C. Knepper, and A.L. Sabel Decreased antibiotic utilization after implementation of a guideline for inpatient cellulitis and cutaneous abscess Arch Intern Med 171 2011 1072 1079
10. P. Gabow, S. Eisert, and R. Wright Denver Health: a model for the integration of a public hospital and community health centers Ann Intern Med 138 2003 143 149
11. US Department of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research (CDER). Draft guidance for industry: acute bacterial skin and skin structure infections - developing drugs for treatment. August 2010. Available at: http://www.fda.gov/downloads/Drugs/ GuidanceComplianceRegulatoryInformation/Guidances/ucm071185.pdf. Accessed February 6, 2013.
12. C. Liu, A. Bayer, and S.E. Cosgrove Clinical practice guidelines by the Infectious Diseases Society of America for the treatment of methicillin- resistant Staphylococcus aureus infections in adults and children: executive summary Clin Infect Dis 52 2011 285 292
13. A. Jeng, M. Beheshti, and J. Li The role of beta-hemolytic streptococci in causing diffuse, nonculturable cellulitis: a prospective investigation Medicine 89 2010 217 226
14. G.J. Moran, A. Krishnadasan, and R.J. Gorwitz Methicillin-resistant S. aureus infections among patients in the emergency department N Engl J Med 355 2006 666 674
15. D.L. Stevens, A.L. Bisno, and H.F. Chambers Practice guidelines for the diagnosis and management of skin and soft-tissue infections Clin Infect Dis 41 2005 1373 1406
16. D.J. Pallin, W.D. Binder, and M.B. Allen Clinical trial: comparative effectiveness of cephalexin plus trimethoprim-sulfamethoxazole versus cephalexin alone for treatment of uncomplicated cellulitis: a randomized controlled trial Clin Infect Dis 56 2013 1754 1762
17. ClinicalTrials.gov: A Service of the U.S. National Institutes of Health (NCT00729937). Available at: http://www.clinicaltrials.gov/. Accessed August 8, 2013.
18. G.R. Schmitz, D. Bruner, and R. Pitotti Randomized controlled trial of trimethoprim-sulfamethoxazole for uncomplicated skin abscesses in patients at risk for community-associated methicillin-resistant Staphylococcus aureus infection Ann Emerg Med 56 2010 283 287
19. M. Duong, S. Markwell, and J. Peter Randomized, controlled trial of antibiotics in the management of community-acquired skin abscesses in the pediatric patient Ann Emerg Med 55 2010 401 407
20. M.J. Hepburn, D.P. Dooley, and P.J. Skidmore Comparison of short-course (5 days) and standard (10 days) treatment for uncomplicated cellulitis Arch Intern Med 164 2004 1669 1674
21. P. Prokocimer, C. De Anda, and E. Fang Tedizolid phosphate vs linezolid for treatment of acute bacterial skin and skin structure infections: the ESTABLISH-1 randomized trial JAMA 309 2013 559 569
22. B. Spellberg, H. Boucher, and J. Bradley To treat or not to treat: adjunctive antibiotics for uncomplicated abscesses Ann Emerg Med 57 2011 183 185
23. A. Hankin, and W.W. Everett Are antibiotics necessary after incision and drainage of a cutaneous abscess? Ann Emerg Med 50 2007 49 51
24. D.J. Elliott, T.E. Zaoutis, and A.B. Troxel Empiric antimicrobial therapy for pediatric skin and soft-tissue infections in the era of methicillin-resistant Staphylococcus aureus Pediatrics 123 2009 e959 e966
25. K.J. Madaras-Kelly, R.E. Remington, and C.M. Oliphant Efficacy of oral beta-lactam versus non-beta-lactam treatment of uncomplicated cellulitis Am J Med 121 2008 419 425
26. R.D. Wells, P. Mason, and J. Roarty Comparison of initial antibiotic choice and treatment of cellulitis in the pre- and post-community-acquired methicillin-resistant Staphylococcus aureus eras Am J Emerg Med 27 2009 436 439