Changing epidemiology of Clostridium difficile-associated disease in children

Infection Control and Hospital Epidemiology

Volumn 28, Issue 11, 2007, Pages 1233-1235

  Benson, Lacey ^a   Song, Xiaoyan ^b,d   Campos, Joseph ^c   Singh, Nalini ^c,d,e,f  

^a CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c GEORGE WASHINGTON UNIVERSITY SCHOOL OF MEDICINE AND HEALTH SCIENCES   (United States)

^d CHILDREN'S NATIONAL MEDICAL CENTER   (United States)

^e GEORGE WASHINGTON UNIVERSITY   (United States)

^f GEORGE WASHINGTON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL TOXIN;

ARTICLE; BACTERIAL INFECTION; CHILD; CLOSTRIDIUM DIFFICILE; CLOSTRIDIUM DIFFICILE ASSOCIATED DISEASE; COHORT ANALYSIS; EMERGENCY WARD; FECES ANALYSIS; HIGH RISK POPULATION; HOSPITAL ADMISSION; HOSPITAL PATIENT; HUMAN; INCIDENCE; INFANT; NEWBORN; NEWBORN INTENSIVE CARE; OBSERVATIONAL STUDY; OUTPATIENT; POISSON DISTRIBUTION; RETROSPECTIVE STUDY; RISK FACTOR; TIME SERIES ANALYSIS;

CHILD, PRESCHOOL; CLOSTRIDIUM DIFFICILE; COMMUNITY-ACQUIRED INFECTIONS; DISTRICT OF COLUMBIA; ENTEROCOLITIS, PSEUDOMEMBRANOUS; HOSPITALS, PEDIATRIC; HUMANS; INCIDENCE; INFANT; INFANT, NEWBORN; RETROSPECTIVE STUDIES;

EID: 35348991541     PISSN: 0899823X     EISSN: None     Source Type: Journal    
DOI: 10.1086/520732     Document Type: Article

References (11)

1. McDonald LC, Killgore GE, Thompson A, et al. An epidemic, toxin gene-variant strain of Clostridium difficile. N Engl J Med 2005; 353:2433-2441.
2. Pepin J, Alary ME, Valiquette L, et al. Increasing risk of relapse after treatment of Clostridium difficile colitis in Quebec, Canada. Clin Infect Dis 2005; 40:1591-1597.
3. Pepin J, Valiquette L, Alary ME, et al. Clostridium difficile-associated diarrhea in a region of Quebec from 1991 to 2003: a changing pattern of disease severity. CMAJ 2004; 171:466-472.
4. Al-Jumaili IJ, Shibley M, Lishman AH, Record CO. Incidence and origin of Clostridium difficile in neonates. J Clin Microbiol 1984; 19:77-78.
5. Larson HE, Barclay FE, Honour P, Hill ID. Epidemiology of Clostridium difficile in infants. J Infect Dis 1982; 146:727-733.
6. Han VK, Sayed H, Chance GW, et al. An outbreak of Clostridium difficile necrotizing enterocolitis: a case for oral vancomycin therapy? Pediatrics 1983; 71:935-941.
7. Centers for Disease Control and Prevention. Severe Clostridium difficile associated disease in populations previously at low risk - four states, 2005. MMWR Morb Mortal Wkly Rep 2005; 54:1201-1205.
8. Klein EJ, Boster DR, Stapp JR, et al. Diarrhea etiology in a children's hospital emergency department: a prospective cohort study. Clin Infect Dis 2006; 43:807-813.
9. Johnson S, Kent SA, O'Leary KJ, et al. Fatal pseudomembranous colitis associated with a variant Clostridium difficile not detected by toxin A immunoassay. Ann Intern Med 2001; 135:434-438.
10. Loo VG, Miller MA, Oughton M, et al. A predominantly clonal multiinstitutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality. N Engl J Med 2005; 353:2442-2449.
11. Poutanen S, Simor AE. Clostridium difficile associated diarrhea in adults. CMAJ 2004; 171:51-58.