Effect of Arctium lappa (burdock) extract on canine dermal fibroblasts

Veterinary Immunology and Immunopathology

Volumn 156, Issue 3-4, 2013, Pages 159-166

  Pomari, Elena ^a   Stefanon, Bruno ^a   Colitti, Monica ^a  

^a UNIVERSITY OF UDINE   (Italy)

Author keywords

Arctium lappa; Dermal fibroblasts; Dog; RNAseq

Indexed keywords

ARCTIUM LAPPA ROOT EXTRACT; BETA CATENIN; CHONDROITIN SULFATE; DISHEVELED 3; FRIZZLED 5; FRIZZLED PROTEIN; GLYCOGEN SYNTHASE KINASE 3BETA; HYDROGEN PEROXIDE; MANGANESE SUPEROXIDE DISMUTASE; N ACETYLGALACTOSAMINYLTRANSFERASE; N ACETYLGALACTOSAMINYLTRANSFERASE 2; PLANT EXTRACT; UNCLASSIFIED DRUG;

ANIMAL CELL; ARCTIUM LAPPA; ARTICLE; CELL ADHESION; CELL VIABILITY; CONTROLLED STUDY; DOWN REGULATION; GENE EXPRESSION; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PLANT ROOT; SIGNAL TRANSDUCTION; SKIN FIBROBLAST; UPREGULATION;

ARCTIUM; ARCTIUM LAPPA; CANIS FAMILIARIS;

ARCTIUM LAPPA; DERMAL FIBROBLASTS; DOG; RNASEQ;

ANIMALS; ARCTIUM; CELL ADHESION; CELL SURVIVAL; CELLS, CULTURED; DOGS; FIBROBLASTS; PLANT EXTRACTS; SKIN; TRANSCRIPTOME;

EID: 84888060422     PISSN: 01652427     EISSN: 18732534     Source Type: Journal    
DOI: 10.1016/j.vetimm.2013.10.008     Document Type: Article

References (48)

1. Bickers D.R., Athar M. Oxidative stress in the pathogenesis of skin disease. J. Invest. Dermatol. 2006, 126:2565-2575.
2. Bielefeld K.A., Amini-Nik S., Alman B.A. Cutaneous wound healing: recruiting developmental pathways for regeneration. Cell. Mol. Life Sci. 2012, 70(12):2059-2081.
3. Bustin S.A., Benes V., Garson J.A., Hellemans J., Huggett J., Kubista M., Mueller R., Nolan T., Pfaffl M.W., Shipley G.L., Vandesompele J., Wittwer C.T. The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments. Clin. Chem. 2009, 55:611-622.
4. Chan Y.S., Cheng L.N., Wu J.H., Chan E., Kwan Y.W., Lee S.M., Leung G.P., Yu P.H., Chan S.W. A review of the pharmacological effects of Arctium lappa (burdock). Inflammopharmacology 2011, 19:245-254.
5. Chen F., Wu A., Chen C. The influence of different treatments on the free radical scavenging activity of burdock and variations of its active components. Food Chem. 2004, 86:479-484.
6. Colitti M., Gaspardo B., Della Pria A., Scaini C., Stefanon B. Transcriptome modification of white blood cells after dietary administration of curcumin and non-steroidal anti-inflammatory drug in osteoarthritic affected dogs. Vet. Immunol. Immunopathol. 2012, 147:136-146.
7. Crampton S.P., Wu B., Park E.J., Kim J.H., Solomon C., Waterman M.L., Hughes C.C. Integration of the beta-catenin-dependent Wnt pathway with integrin signaling through the adaptor molecule Grb2. PLoS ONE 2009, 4(11):e7841.
8. Farinacci M., Colitti M., Sgorlon S., Stefanon B. Immunomodulatory activity of plant residues on ovine neutrophils. Vet. Immunol. Immunopathol. 2008, 126:54-63.
9. Farinacci M., Colitti M., Stefanon B. Modulation of ovine neutrophil function and apoptosis by standardized extracts of Echinacea angustifolia, Butea frondosa and Curcuma longa. Vet. Immunol. Immunopathol. 2009, 128:366-373.
10. Funato Y., Michiue T., Asashima M., Miki H. The thioredoxin-related redox-regulating protein nucleoredoxin inhibits Wnt-beta-catenin signalling through dishevelled. Nat. Cell Biol. 2006, 8(5):501-508.
11. Guo F., Carter D.E., Mukhopadhyay A., Leask A. Gingival fibroblasts display reduced adhesion and spreading on extracellular matrix: a possible basis for scarless tissue repair?. PLoS ONE 2011, 6:e27097.
12. Hurd T.R., DeGennaro M., Lehmann R. Redox regulation of cell migration and adhesion. Trends Cell Biol. 2012, 22(2):107-115.
13. Iriti M., Vitalini S., Fico G., Faoro F. Neuroprotective herbs and foods from different traditional medicines and diets. Molecules 2010, 15(5):3517-3555.
14. Kennedy L., Shi-Wen X., Carter D.E., Abraham D.J., Leask A. Fibroblast adhesion results in the induction of a matrix remodeling gene expression program. Matrix Biol. 2008, 27(4):274-281.
15. Kim J., Lee Is., Park S., Choue R. Effects of Scutellariae radix and Aloe vera gel extracts on immunoglobulin E and cytokine levels in atopic dermatitis NC/Nga mice. J. Ethnopharmacol. 2010, 132(2):529-532.
16. Kim W., Kim M., Jho E.H. Wnt/β-catenin signalling: from plasma membrane to nucleus. Biochem. J. 2013, 450(1):9-21.
17. Klyubin I.V., Kirpichnikova K.M., Gamaley I.A. Hydrogen peroxide-induced chemotaxis of mouse peritoneal neutrophils. Eur. J. Cell Biol. 1996, 70:347-351.
18. Komiya Y., Habas R. Wnt signal transduction pathways. Organogenesis 2008, 4(2):68-75.
19. Korswagen H.C. Regulation of the Wnt/beta-catenin pathway by redox signaling. Dev. Cell 2006, 10(6):687-688.
20. Lam A.P., Gottardi C.J. β-Catenin signaling: a novel mediator of fibrosis and potential therapeutic target. Curr. Opin. Rheumatol. 2011, 23(6):562-567.
21. Lin C.C., Lu J.M., Yang J.J., Chuang S.C., Ujiie T. Anti-inflammatory and radical scavenge effects of Arctium lappa. Am. J. Chin. Med. 1996, 24:127-137.
22. Lin S., Lin C., Lin C., Lin Y., Chen C., Chen I., Wang L. Hepatoprotective effects of Arctium lappa Linne on liver injuries induced by chronic ethanol consumption and potentiated by carbon tetrachloride. J. Biomed. Sci. 2002, 9:401-409.
23. -δδCT method. Methods 2001, 25:402-408.
24. Loo A.E., Ho R., Halliwell B. Mechanism of hydrogen peroxide-induced keratinocyte migration in a scratch-wound model. Free Radic. Biol. Med. 2011, 51(4):884-892.
25. Loo A.E., Halliwell B. Effects of hydrogen peroxide in a keratinocyte-fibroblast co-culture model of wound healing. Biochem. Biophys. Res. Commun. 2012, 423(2):253-258.
26. Midwood K.S., Mao Y., Hsia H.C., Valenick L.V., Schwarzbauer J.E. Modulation of cell-fibronectin matrix interactions during tissue repair. J. Investig. Dermatol. Symp. Proc. 2006, 11(1):73-78.
27. Mikami T., Kitagawa H. Biosynthesis and function of chondroitin sulfate. Biochim. Biophys. Acta 2013, 1830(10):4719-4733.
28. Mukherjee P.K., Maity N., Nema N.K., Sarkar B.K. Bioactive compounds from natural resources against skin aging. Phytomedicine 2011, 19:64-73.
29. Nakayama F., Hagiwara A., Yamamoto T., Akashi M. Hydrogen peroxide as a potential mediator of the transcriptional regulation of heparan sulphate biosynthesis in keratinocytes. Cell. Mol. Biol. Lett. 2008, 13(3):475-492.
30. Ogawa H., Hatano S., Sugiura N., Nagai N., Sato T., Shimizu K., Kimata K., Narimatsu H., Watanabe H. Chondroitin sulfate synthase-2 is necessary for chain extension of chondroitin sulfate but not critical for skeletal development. PLoS ONE 2012, 7(8):e43806.
31. Olivry T. What can dogs bring to atopic dermatitis research?. Chem. Immunol. Allergy 2012, 96:61-72.
32. Pandey K.B., Rizvi S.I. Plant polyphenols as dietary antioxidants in human health and disease. Oxid. Med. Cell Longev. 2009, 2:270-278.
33. Proksch E., Brandner J.M., Jensen J.M. The skin: an indispensable barrier. Exp. Dermatol. 2008, 17:1063-1072.
34. Pruett S.B., Loftis A.Y. Characteristics of MTT as an indicator of viability and respiratory burst activity of human neutrophils. Int. Arch. Allergy Appl. Immunol. 1990, 92(2):189-192.
35. Rizzato C., Canzian F., Rudnai P., Gurzau E., Stein A., Koppova K., Hemminki K., Kumar R., Campa D. Interaction between functional polymorphic variants in cytokine genes, established risk factors and susceptibility to basal cell carcinoma of skin. Carcinogenesis 2011, 32(12):1849-1854.
36. Rozen S., Skaletsky H.J. Primer3 on the WWW for general users and for biologist programmers. Bioinformatics Methods and Protocols: Methods in Molecular Biology 2000, 365-386. Humana Press.
37. Salbach J., Rachner T.D., Rauner M., Hempel U., Anderegg U., Franz S., Simon J.C., Hofbauer L.C. Regenerative potential of glycosaminoglycans for skin and bone. J. Mol. Med. 2012, 90(6):625-635.
38. Scharffetter-Kochanek K., Brenneisen P., Wenk J., Herrmann G., Ma W., Kuhr L., Meewes C., Wlaschek M. Photoaging of the skin from phenotype to mechanisms. Exp. Gerontol. 2000, 35(3):307-316.
39. Sgorlon S., Colitti M., Asquini E., Ferrarini A., Pallavicini A., Stefanon B. Administration of botanicals with the diet regulates gene expression in peripheral blood cells of Sarda sheep during ACTH challenge. Domest. Anim. Endocrinol. 2012, 43(3):213-226.
40. Shin S.Y., Kim C.G., Jho E.H., Rho M.S., Kim Y.S., Kim Y.H., Lee Y.H. Hydrogen peroxide negatively modulates Wnt signaling through down regulation of beta-catenin. Cancer Lett. 2004, 212(2):225-231.
41. Sohn E.H., Jang S.A., Joo H., Park S., Kang S.C., Lee C.H., Kim S.Y. Anti-allergic and anti-inflammatory effects of butanol extract from Arctium Lappa L. Clin. Mol. Allergy 2011, 9:4.
42. SPSS® Statistical Package for Social Science SPSS Advanced Statistics 16.0 2007, SPSS Inc., Chicago, IL.
43. Szabó C., Ischiropoulos H., Radi R. Peroxynitrite: biochemistry, pathophysiology and development of therapeutics. Nat. Rev. Drug Discov. 2007, 6(8):662-680.
44. Tapsell L.C., Hemphill I., Cobiac L., Patch C.S., Sullivan D.R., Fenech M., Roodenrys S., Keogh J.B., Clifton P.M., Williams P.G., Fazio V.A., Inge K.E. Health benefits of herbs and spices: the past, the present, the future. Med. J. Aust. 2006, 185(Suppl. 4):S4-S24.
45. Trouba K.J., Hamadeh H.K., Amin R.P., Germolec D.R. Oxidative stress and its role in skin disease. Antioxid. Redox Signal. 2002, 4:665-673.
46. Uyama T., Kitagawa H., Tamura J.J., Sugahara K. Molecular cloning and expression of human chondroitin N-acetylgalactosaminyltransferase: the key enzyme for chain initiation and elongation of chondroitin/dermatan sulfate on the protein linkage region tetrasaccharide shared by heparin/heparan sulfate. J. Biol. Chem. 2002, 277(11):8841-8846.
47. Watanabe Y., Takeuchi K., Higa Onaga S., Sato M., Tsujita M., Abe M., Natsume R., Li M., Furuichi T., Saeki M., Izumikawa T., Hasegawa A., Yokoyama M., Ikegawa S., Sakimura K., Amizuka N., Kitagawa H., Igarashi M. Chondroitin sulfate N-acetylgalactosaminyltransferase-1 is required for normal cartilage development. Biochem. J. 2010, 432:47-55.
48. Wu J.G., Wu J.Z., Sun L.N., Han T., Du J., Ye Q., Zhang H., Zhang Y.G. Ameliorative effects of arctiin from Arctium lappa on experimental glomerulonephritis in rats. Phytomedicine 2009, 16(11):1033-1041.