Pro-inflammatory effect of cystic fibrosis sputum microparticles in the murine lung

Journal of Cystic Fibrosis

Volumn 12, Issue 6, 2013, Pages 721-728

  Porro, Chiara ^a   Di Gioia, Sante ^a   Trotta, Teresa ^a   Lepore, Silvia ^b   Panaro, Maria Antonietta ^c   Battaglino, Anna ^d   Ratclif, Luigi ^d   Castellani, Stefano ^a   Bufo, Pantaleo ^a   Martinez, Maria Carmen ^e   Conese, Massimo ^a  

^a UNIVERSITY OF FOGGIA   (Italy)

^b IRCCS CROB Rionero in Vulture   (Italy)

^c UNIVERSITY OF BARI   (Italy)

^d Ospedale G Tatarella   (Italy)

^e UNIVERSITÉ D'ANGERS   (France)

Author keywords

Cystic fibrosis; Lipopolysaccharide; Lung inflammation; Macrophages; Neutrophils; Primary ciliary dyskinesia

Indexed keywords

C REACTIVE PROTEIN; LIPOPOLYSACCHARIDE;

ACUTE LUNG INJURY; ADULT; AIRWAY OBSTRUCTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL INFILTRATION; CILIARY DYSKINESIA; CLINICAL ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; FORCED EXPIRATORY VOLUME; GRANULOCYTE; HISTOPATHOLOGY; HUMAN; HUMAN CELL; INFLAMMATORY CELL; INFLAMMATORY INFILTRATE; LEUKOCYTE DIFFERENTIAL COUNT; LIMULUS LYSATE TEST; LUNG FIBROSIS; LUNG LAVAGE; MACROPHAGE; MALE; MEMBRANE MICROPARTICLE; MOUSE; NEUTROPHIL; NONHUMAN; PNEUMONIA; PRIMARY CILIARY DISKINESIA; SPUTUM ANALYSIS;

CYSTIC FIBROSIS; LIPOPOLYSACCHARIDE; LUNG INFLAMMATION; MACROPHAGES; NEUTROPHILS; PRIMARY CILIARY DYSKINESIA;

ADULT; ANIMALS; ANTIGENS, CD; BRONCHOALVEOLAR LAVAGE FLUID; CELL ADHESION MOLECULES; CELL-DERIVED MICROPARTICLES; CYSTIC FIBROSIS; HUMANS; LIPOPOLYSACCHARIDES; MICE; SPUTUM; YOUNG ADULT;

EID: 84888055209     PISSN: 15691993     EISSN: 18735010     Source Type: Journal    
DOI: 10.1016/j.jcf.2013.03.002     Document Type: Article

References (37)

1. Conese M. Cystic fibrosis and the innate immune system: therapeutic implications. Endocr Metab Immune Disord Drug Targets 2011, 11:8-22.
2. Cohen T.S., Prince A. Cystic fibrosis: a mucosal immunodeficiency syndrome. Nat Med 2012, 18:509-519.
3. Hartl D., Gaggar A., Bruscia E., Hector A., Marcos V., Jung A., et al. Innate immunity in cystic fibrosis lung disease. J Cyst Fibros 2012, 11:363-382.
4. Watt A.P., Courtney J., Moore J., Ennis M., Elborn J.S. Neutrophil cell death, activation and bacterial infection in cystic fibrosis. Thorax 2005, 60:659-664.
5. Hartl D., Latzin P., Hordijk P., Marcos V., Rudolph C., Woischnik M., et al. Cleavage of CXCR1 on neutrophils disables bacterial killing in cystic fibrosis lung disease. Nat Med 2007, 13:1423-1430.
6. Wolf P. The nature and significance of platelet products in human plasma. Br J Haematol 1967, 13:269-288.
7. Martinez M.C., Andriantsitohaina R. Microparticles in angiogenesis: therapeutic potential. Circ Res 2011, 109:110-119.
8. Tual-Chalot S., Leonetti D., Andriantsitohaina R., Martinez M.C. Microvesicles: intercellular vectors of biological messages. Mol Interv 2011, 11:88-94.
9. Mutschler D.K., Larsson A.O., Basu S., Nordgren A., Eriksson M.B. Effects of mechanical ventilation on platelet microparticles in bronchoalveolar lavage fluid. Thromb Res 2002, 108:215-220.
10. Bastarache J.A., Fremont R.D., Kropski J.A., Bossert F.R., Ware L.B. Procoagulant alveolar microparticles in the lungs of patients with acute respiratory distress syndrome. Am J Physiol Lung Cell Mol Physiol 2009, 297:L1035-L1041.
11. McVey M., Tabuchi A., Kuebler W.M. Microparticles and acute lung injury. Am J Physiol Lung Cell Mol Physiol 2012, 303:L364-L381.
12. Porro C., Lepore S., Trotta T., Castellani S., Ratclif L., Battaglino A., et al. Isolation and characterization of microparticles in sputum of cystic fibrosis patients. Respir Res 2010, 11:94.
13. Livraghi A., Randell S.H. Cystic fibrosis and other respiratory diseases of impaired mucus clearance. Toxicol Pathol 2007, 35:116-129.
14. Stenbit A.E., Flume P.A. Pulmonary exacerbations in cystic fibrosis. Curr Opin Pulm Med 2011, 17:442-447.
15. Levy H., Kalish L.A., Huntington I., Weller N., Gerard C., Silverman E.K., et al. Inflammatory markers of lung disease in adult patients with cystic fibrosis. Pediatr Pulmonol 2007, 42:256-262.
16. Saiman L., Siegel J. Infection control recommendations for patients with cystic fibrosis: microbiology, important pathogens, and infection control practices to prevent patient-to-patient transmission. Am J Infect Control 2003, 31:S1-S62.
17. Agouni A., Lagrue-Lak-Hal A.H., Ducluzeau P.H., Mostefai H.A., Draunet-Busson C., Leftheriotis G., et al. Endothelial dysfunction caused by circulating microparticles from patients with metabolic syndrome. Am J Pathol 2008, 173:1210-1219.
18. Boyum A. Isolation of lymphocytes, granulocytes and macrophages. Scand J Immunol 1976, (Suppl. 5):9-15.
19. Buesing K.L., Densmore J.C., Kaul S., Pritchard K.A., Jarzembowski J.A., Gourlay D.M., et al. Endothelial microparticles induce inflammation in acute lung injury. J Surg Res 2011, 166:32-39.
20. Densmore J.C., Signorino P.R., Ou J., Hatoum O.A., Rowe J.J., Shi Y., et al. Endothelium-derived microparticles induce endothelial dysfunction and acute lung injury. Shock 2006, 26:464-471.
21. Fothergill J.L., Mowat E., Ledson M.J., Walshaw M.J., Winstanley C. Fluctuations in phenotypes and genotypes within populations of Pseudomonas aeruginosa in the cystic fibrosis lung during pulmonary exacerbations. J Med Microbiol 2010, 59:472-481.
22. Tunney M.M., Klem E.R., Fodor A.A., Gilpin D.F., Moriarty T.F., McGrath S.J., et al. Use of culture and molecular analysis to determine the effect of antibiotic treatment on microbial community diversity and abundance during exacerbation in patients with cystic fibrosis. Thorax 2011, 66:579-584.
23. Mause S.F., Weber C. Microparticles: protagonists of a novel communication network for intercellular information exchange. Circ Res 2010, 107:1047-1057.
24. Sagel S.D., Davis S.D., Campisi P., Dell S.D. Update of respiratory tract disease in children with primary ciliary dyskinesia. Proc Am Thorac Soc 2010, 8:438-443.
25. Martinez M.C., Tual-Chalot S., Leonetti D., Andriantsitohaina R. Microparticles: targets and tools in cardiovascular disease. Trends Pharmacol Sci 2011, 32:659-665.
26. Aird W.C. The role of the endothelium in severe sepsis and multiple organ dysfunction syndrome. Blood 2003, 101:3765-3777.
27. Guo R.F., Riedemann N.C., Ward P.A. Role of C5a-C5aR interaction in sepsis. Shock 2004, 21:1-7.
28. Worlitzsch D., Tarran R., Ulrich M., Schwab U., Cekici A., Meyer K.C., et al. Effects of reduced mucus oxygen concentration in airway Pseudomonas infections of cystic fibrosis patients. J Clin Invest 2002, 109:317-325.
29. Bauman S.J., Kuehn M.J. Pseudomonas aeruginosa vesicles associate with and are internalized by human lung epithelial cells. BMC Microbiol 2009, 9:26.
30. Muhlebach M.S., Noah T.L. Endotoxin activity and inflammatory markers in the airways of young patients with cystic fibrosis. Am J Respir Crit Care Med 2002, 165:911-915.
31. Bauman S.J., Kuehn M.J. Purification of outer membrane vesicles from Pseudomonas aeruginosa and their activation of an IL-8 response. Microbes Infect 2006, 8:2400-2408.
32. Ngan D.A., Wilcox P.G., Aldaabil M., Li Y., Leipsic J.A., Sin D.D., et al. The relationship of systemic inflammation to prior hospitalization in adult patients with cystic fibrosis. BMC Pulm Med 2012, 12:3.
33. Trotta T., Di Gioia S., Piro D., Lepore S., Cantatore S., Porro C., et al. Effect of acute lung injury on VLA-4 and CXCR4 expression in resident and circulating hematopoietic stem/progenitor cells. Respiration 2013, 85:252-264.
34. Watanabe J., Marathe G.K., Neilsen P.O., Weyrich A.S., Harrison K.A., Murphy R.C., et al. Endotoxins stimulate neutrophil adhesion followed by synthesis and release of platelet-activating factor in microparticles. J Biol Chem 2003, 278:33161-33168.
35. Angelillo-Scherrer A. Leukocyte-derived microparticles in vascular homeostasis. Circ Res 2012, 110:356-369.
36. Mesri M., Altieri D.C. Endothelial cell activation by leukocyte microparticles. J Immunol 1998, 161:4382-4387.
37. Mesri M., Altieri D.C. Leukocyte microparticles stimulate endothelial cell cytokine release and tissue factor induction in a JNK1 signaling pathway. J Biol Chem 1999, 274:23111-23118.