Association of a polymorphism in mitochondrial transcription factor A (TFAM) with Parkinson's disease dementia but not dementia with Lewy bodies

Neuroscience Letters

Volumn 557, Issue PB, 2013, Pages 177-180

  Gatt, Ariana P ^a   Jones, Emma L ^a   Francis, Paul T ^a   Ballard, Clive ^a   Bateman, Joseph M ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Dementia; Lewy body; Mitochondria; Parkinson's; Polymorphism; TFAM

Indexed keywords

MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A;

AGED; ARTICLE; CONTROLLED STUDY; DIFFUSE LEWY BODY DISEASE; FEMALE; GENE DOSAGE; GENE FREQUENCY; GENETIC ASSOCIATION; GENOTYPE; HOMOZYGOSITY; HUMAN; MAJOR CLINICAL STUDY; MALE; PARKINSON DISEASE; PREFRONTAL CORTEX; PRIORITY JOURNAL; SEX DIFFERENCE; SINGLE NUCLEOTIDE POLYMORPHISM;

DEMENTIA; LEWY BODY; MITOCHONDRIA; PARKINSON'S; POLYMORPHISM; TFAM;

AGED; DEMENTIA; DNA-BINDING PROTEINS; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOTYPE; HUMANS; LEWY BODY DISEASE; MALE; MITOCHONDRIAL PROTEINS; PARKINSON DISEASE; POLYMERASE CHAIN REACTION; POLYMORPHISM, SINGLE NUCLEOTIDE; SEX CHARACTERISTICS; TRANSCRIPTION FACTORS;

EID: 84888027715     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2013.10.045     Document Type: Article

References (29)

1. Aarsland D., Ballard C., Larsen J.P., McKeith I. A comparative study of psychiatric symptoms in dementia with Lewy bodies and Parkinson's disease with and without dementia. International Journal of Geriatric Psychiatry 2001, 16:528-536.
2. Aarsland D., Kurz M.W. The epidemiology of dementia associated with Parkinson disease. Journal of the Neurological Sciences 2010, 289:18-22.
3. Aarsland D., Litvan I., Salmon D., Galasko D., Wentzel-Larsen T., Larsen J.P. Performance on the dementia rating scale in Parkinson's disease with dementia and dementia with Lewy bodies: comparison with progressive supranuclear palsy and Alzheimer's disease. Journal of Neurology, Neurosurgery, and Psychiatry 2003, 74:1215-1220.
4. Aarsland D., Zaccai J., Brayne C. A systematic review of prevalence studies of dementia in Parkinson's disease. Movement Disorders 2005, 20:1255-1263.
5. Ballard C., Ziabreva I., Perry R., Larsen J.P., O'Brien J., McKeith I., Perry E., Aarsland D. Differences in neuropathologic characteristics across the Lewy body dementia spectrum. Neurology 2006, 67:1931-1934.
6. Belin A.C., Björk B.F., Westerlund M., Galter D., Sydow O., Lind C., Pernold K., Rosvall L., Håkansson A., Winblad B., Nissbrandt H., Graff C., Olson L. Association study of two genetic variants in mitochondrial transcription factor A (TFAM) in Alzheimer's and Parkinson's disease. Neuroscience Letters 2007, 420:257-262.
7. Bertram L., McQueen M.B., Mullin K., Blacker D., Tanzi R.E. Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. Nature Genetics 2007, 39:17-23.
8. Burn D.J., McKeith I.G. Current treatment of dementia with Lewy bodies and dementia associated with Parkinson's disease. Movement Disorders: Official Journal of the Movement Disorder Society 2003, 18(Suppl 6):S72-S79.
9. Copeland W.C. Inherited mitochondrial diseases of DNA replication. Annual Review of Medicine 2008, 59:131-146.
10. Coskun P.E., Beal M.F., Wallace D.C. Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:10726-10731.
11. Downes J.J., Priestley N.M., Doran M., Ferran J., Ghadiali E., Cooper P. Intellectual, mnemonic, and frontal functions in dementia with Lewy bodies: a comparison with early and advanced Parkinson's disease. Behavioural Neurology 1998, 11:173-183.
12. Ekstrand M.I., Terzioglu M., Galter D., Zhu S., Hofstetter C., Lindqvist E., Thams S., Bergstrand A., Hansson F.S., Trifunovic A., Hoffer B., Cullheim S., Mohammed A.H., Olson L., Larsson N.-G. Progressive parkinsonism in mice with respiratory-chain-deficient dopamine neurons. Proceedings of the National Academy of Sciences 2007, 104:1325-1330.
13. Gaweda-Walerych K., Safranow K., Maruszak A., Bialecka M., Klodowska-Duda G., Czyzewski K., Slawek J., Rudzinska M., Styczynska M., Opala G., Drozdzik M., Kurzawski M., Szczudlik A., Canter J.A., Barcikowska M., Zekanowski C. Mitochondrial transcription factor A variants and the risk of Parkinson's disease. Neuroscience Letters 2010, 469:24-29.
14. Good C.H., Hoffman A.F., Hoffer B.J., Chefer V.I., Shippenberg T.S., Backman C.M., Larsson N.G., Olson L., Gellhaar S., Galter D., Lupica C.R. Impaired nigrostriatal function precedes behavioral deficits in a genetic mitochondrial model of Parkinson's disease. FASEB Journal: Official Publication of the Federation of American Societies for Experimental Biology 2011, 25:1333-1344.
15. Günther C., Hadeln K.v., Müller-Thomsen T., Alberici A., Binetti G., Hock C., Nitsch R.M., Stoppe G., Reiss J., Gal A., Finckh U. Possible association of mitochondrial transcription factor A (TFAM) genotype with sporadic Alzheimer disease. Neuroscience Letters 2004, 369:219-223.
16. Hughes A.J., Daniel S.E., Lees A.J. Improved accuracy of clinical diagnosis of Lewy body Parkinson's disease. Neurology 2001, 57:1497-1499.
17. Laumet G., Chouraki V., Grenier-Boley B., Legry V., Heath S., Zelenika D., Fievet N., Hannequin D., Delepine M., Pasquier F., Hanon O., Brice A., Epelbaum J., Berr C., Dartigues J.F., Tzourio C., Campion D., Lathrop M., Bertram L., Amouyel P., Lambert J.C. Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study. Journal of Alzheimer's Disease 2010, 20:1181-1188.
18. Lippa C.F., Duda J.E., Grossman M., Hurtig H.I., Aarsland D., Boeve B.F., Brooks D.J., Dickson D.W., Dubois B., Emre M., Fahn S., Farmer J.M., Galasko D., Galvin J.E., Goetz C.G., Growdon J.H., Gwinn-Hardy K.A., Hardy J., Heutink P., Iwatsubo T., Kosaka K., Lee V.M., Leverenz J.B., Masliah E., McKeith I.G., Nussbaum R.L., Olanow C.W., Ravina B.M., Singleton A.B., Tanner C.M., Trojanowski J.Q., Wszolek Z.K. DLB and PDD boundary issues: diagnosis, treatment, molecular pathology, and biomarkers. Neurology 2007, 68:812-819.
19. Malik A.N., Shahni R., Iqbal M.M. Increased peripheral blood mitochondrial DNA in type 2 diabetic patients with nephropathy. Diabetes Research and Clinical Practice 2009, 86:e22-e24.
20. Mayer A., Lahr G., Swaab D.F., Pilgrim C., Reisert I. The Y-chromosomal genes SRY and ZFY are transcribed in adult human brain. Neurogenetics 1998, 1:281-288.
21. McKeith I.G., Dickson D.W., Lowe J., Emre M., O'Brien J.T., Feldman H., Cummings J., Duda J.E., Lippa C., Perry E.K., Aarsland D., Arai H., Ballard C.G., Boeve B., Burn D.J., Costa D., Del Ser T., Dubois B., Galasko D., Gauthier S., Goetz C.G., Gomez-Tortosa E., Halliday G., Hansen L.A., Hardy J., Iwatsubo T., Kalaria R.N., Kaufer D., Kenny R.A., Korczyn A., Kosaka K., Lee V.M., Lees A., Litvan I., Londos E., Lopez O.L., Minoshima S., Mizuno Y., Molina J.A., Mukaetova-Ladinska E.B., Pasquier F., Perry R.H., Schulz J.B., Trojanowski J.Q., Yamada M. Diagnosis and management of dementia with Lewy bodies: third report of the DLB Consortium. Neurology 2005, 65:1863-1872.
22. McKeith I.G., Galasko D., Kosaka K., Perry E.K., Dickson D.W., Hansen L.A., Salmon D.P., Lowe J., Mirra S.S., Byrne E.J., Lennox G., Quinn N.P., Edwardson J.A., Ince P.G., Bergeron C., Burns A., Miller B.L., Lovestone S., Collerton D., Jansen E.N., Ballard C., de Vos R.A., Wilcock G.K., Jellinger K.A., Perry R.H. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology 1996, 47:1113-1124.
23. Morimoto N., Miyazaki K., Kurata T., Ikeda Y., Matsuura T., Kang D., Ide T., Abe K. Effect of mitochondrial transcription factor a overexpression on motor neurons in amyotrophic lateral sclerosis model mice. Journal of Neuroscience Research 2012, 90:1200-1208.
24. Mosimann U.P., Rowan E.N., Partington C.E., Collerton D., Littlewood E., O'Brien J.T., Burn D.J., McKeith I.G. Characteristics of visual hallucinations in Parkinson disease dementia and dementia with Lewy bodies. The American Journal of Geriatric Psychiatry: Official Journal of the American Association for Geriatric Psychiatry 2006, 14:153-160.
25. Sherry S.T., Ward M.H., Kholodov M., Baker J., Phan L., Smigielski E.M., Sirotkin K. dbSNP: the NCBI database of genetic variation. Nucleic Acids Research 2001, 29:308-311.
26. Thomas R.R., Khan S.M., Portell F.R., Smigrodzki R.M., Bennett J.P. Recombinant human mitochondrial transcription factor A stimulates mitochondrial biogenesis and ATP synthesis, improves motor function after MPTP, reduces oxidative stress and increases survival after endotoxin. Mitochondrion 2011, 11:108-118.
27. Thomas R.R., Khan S.M., Smigrodzki R.M., Onyango I.G., Dennis J., Khan O.M., Portelli F.R., Bennett J.P. RhTFAM treatment stimulates mitochondrial oxidative metabolism and improves memory in aged mice. Aging 2012, 4:620-635.
28. Wooten G.F., Currie L.J., Bovbjerg V.E., Lee J.K., Patrie J. Are men at greater risk for Parkinson's disease than women?. Journal of Neurology, Neurosurgery, and Psychiatry 2004, 75:637-639.
29. Xu S., Zhong M., Zhang L., Wang Y., Zhou Z., Hao Y., Zhang W., Yang X., Wei A., Pei L., Yu Z. Overexpression of Tfam protects mitochondria against beta-amyloid-induced oxidative damage in SH-SY5Y cells. The FEBS Journal 2009, 276:3800-3809.