The ATP/ADP substrate specificity switch between Toxoplasma gondii NTPDase1 and NTPDase3 is caused by an altered mode of binding of the substrate base

ChemBioChem

Volumn 14, Issue 17, 2013, Pages 2292-2300

  Krug, Ulrike ^a   Totzauer, Robert ^a   Zebisch, Matthias ^a,b   Sträter, Norbert ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

apyrases; kinetic ITC; nucleotides; phosphatases; X ray diffraction

Indexed keywords

NUCLEOSIDE DIPHOSPHATE KINASE; NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 1; NUCLEOSIDE TRIPHOSPHATE DIPHOSPHOHYDROLASE 3; RIBOSE; UNCLASSIFIED DRUG;

ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME SPECIFICITY; GENE SWITCHING; HYDROLYSIS; MUTAGENESIS; NONHUMAN; PRIORITY JOURNAL; TOXOPLASMA GONDII;

PROTOZOA; TOXOPLASMA GONDII;

APYRASES; KINETIC ITC; NUCLEOTIDES; PHOSPHATASES; X-RAY DIFFRACTION;

ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANTIGENS, CD; APYRASE; BINDING SITES; MODELS, MOLECULAR; PYROPHOSPHATASES; SUBSTRATE SPECIFICITY; TOXOPLASMA;

EID: 84888004703     PISSN: 14394227     EISSN: 14397633     Source Type: Journal    
DOI: 10.1002/cbic.201300441     Document Type: Article

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