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Volumn 12, Issue 4, 2013, Pages 89-92

Rilpivirine in the light of the genotypic drug resistance data

Author keywords

Antiretroviral treatment; Drug resistance mutations; NNRTI; Rilpivirne

Indexed keywords

EFAVIRENZ; EMTRICITABINE; LAMIVUDINE; NEVIRAPINE; NONNUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITOR; RILPIVIRINE; STAVUDINE; TENOFOVIR; ZIDOVUDINE;

EID: 84888000976     PISSN: 17301270     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.hivar.2013.09.004     Document Type: Review
Times cited : (2)

References (25)
  • 1
    • 85014459203 scopus 로고    scopus 로고
    • Safety, efficacy, and pharmacokinetics of rilpivirine: Systematic review with an emphasis on resource-limited settings
    • N. Ford, J. Lee, I. Andrieux-Meyer, and A. Calmy Safety, efficacy, and pharmacokinetics of rilpivirine: systematic review with an emphasis on resource-limited settings HIV/AIDS 3 2011 35 44
    • (2011) HIV/AIDS , vol.3 , pp. 35-44
    • Ford, N.1    Lee, J.2    Andrieux-Meyer, I.3    Calmy, A.4
  • 2
    • 84870379961 scopus 로고    scopus 로고
    • A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants
    • B.C. Johnson, G.T. Pauly, G. Rai, D. Patel, J.D. Bauman, and H.L. Baker A comparison of the ability of rilpivirine (TMC278) and selected analogues to inhibit clinically relevant HIV-1 reverse transcriptase mutants Retrovirology 9 2012 99
    • (2012) Retrovirology , vol.9 , pp. 99
    • Johnson, B.C.1    Pauly, G.T.2    Rai, G.3    Patel, D.4    Bauman, J.D.5    Baker, H.L.6
  • 3
    • 75749118495 scopus 로고    scopus 로고
    • TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1
    • H. Azijn, I. Tirry, J. Vingerhoets, M.P. de Bethune, G. Kraus, and K. Boven TMC278, a next-generation nonnucleoside reverse transcriptase inhibitor (NNRTI), active against wild-type and NNRTI-resistant HIV-1 Antimicrob. Agents Chemother. 54 2010 718 727
    • (2010) Antimicrob. Agents Chemother. , vol.54 , pp. 718-727
    • Azijn, H.1    Tirry, I.2    Vingerhoets, J.3    De Bethune, M.P.4    Kraus, G.5    Boven, K.6
  • 4
    • 84876418846 scopus 로고    scopus 로고
    • Rilpivirine vs. Efavirenz in HIV-1 patients with baseline viral load 100,000 copies/ml or less: Week 48 phase III analysis
    • J.M. Molina, N. Clumeck, K. Redant, L. Rimsky, S. Vanveggel, and M. Stevens Rilpivirine vs. efavirenz in HIV-1 patients with baseline viral load 100,000 copies/ml or less: week 48 phase III analysis AIDS 27 2013 889 897
    • (2013) AIDS , vol.27 , pp. 889-897
    • Molina, J.M.1    Clumeck, N.2    Redant, K.3    Rimsky, L.4    Vanveggel, S.5    Stevens, M.6
  • 5
    • 84872965810 scopus 로고    scopus 로고
    • New option for management of HIV-1 infection in treatment-naive patients: Once-daily, fixed-dose combination of rilpivirine-emtricitabine-tenofovir
    • N. Patel, and C.D. Miller New option for management of HIV-1 infection in treatment-naive patients: once-daily, fixed-dose combination of rilpivirine-emtricitabine-tenofovir HIV/AIDS 4 2012 61 71
    • (2012) HIV/AIDS , vol.4 , pp. 61-71
    • Patel, N.1    Miller, C.D.2
  • 6
    • 84862777419 scopus 로고    scopus 로고
    • Efficacy and safety of rilpivirine (TMC278) vs. Efavirenz at 48 weeks in treatment-naive HIV-1-infected patients: Pooled results from the phase 3 double-blind randomized ECHO and THRIVE trials
    • C.J. Cohen, J.M. Molina, P. Cahn, B. Clotet, J. Fourie, and B. Grinsztejn Efficacy and safety of rilpivirine (TMC278) vs. efavirenz at 48 weeks in treatment-naive HIV-1-infected patients: pooled results from the phase 3 double-blind randomized ECHO and THRIVE trials J. Acquir. Immune Defic. Syndr. 60 2012 33 42
    • (2012) J. Acquir. Immune Defic. Syndr. , vol.60 , pp. 33-42
    • Cohen, C.J.1    Molina, J.M.2    Cahn, P.3    Clotet, B.4    Fourie, J.5    Grinsztejn, B.6
  • 7
    • 84875713663 scopus 로고    scopus 로고
    • Cost-effectiveness of efavirenz vs rilpivirine in HIV patients initiating first-line combination antiretroviral therapy
    • M. Bonafede, T. Juday, G. Lenhart, K. Pan, T. Hebden, and T. Correll Cost-effectiveness of efavirenz vs rilpivirine in HIV patients initiating first-line combination antiretroviral therapy J. Med. Econom. 16 2013 552 559
    • (2013) J. Med. Econom. , vol.16 , pp. 552-559
    • Bonafede, M.1    Juday, T.2    Lenhart, G.3    Pan, K.4    Hebden, T.5    Correll, T.6
  • 8
    • 84888015236 scopus 로고    scopus 로고
    • Zasady opieki nad osobami zakażonymi HIV 2013 PTN AIDS, Eko-Press Warszawa (in Polish)
    • Polish Scientific AIDS Society Principles of Care for the HIV-Infected Patients 2013 Zasady opieki nad osobami zakażonymi HIV 2013 2013 PTN AIDS, Eko-Press Warszawa (in Polish)
    • (2013) Principles of Care for the HIV-Infected Patients 2013
  • 10
    • 84864390300 scopus 로고    scopus 로고
    • Panel of prototypical recombinant infectious molecular clones resistant to nevirapine, efavirenz, etravirine, and rilpivirine
    • M. Balamane, V. Varghese, G.L. Melikian, W.J. Fessel, D.A. Katzenstein, and R.W. Shafer Panel of prototypical recombinant infectious molecular clones resistant to nevirapine, efavirenz, etravirine, and rilpivirine Antimicrob. Agents Chemother. 56 2012 4522 4530
    • (2012) Antimicrob. Agents Chemother. , vol.56 , pp. 4522-4530
    • Balamane, M.1    Varghese, V.2    Melikian, G.L.3    Fessel, W.J.4    Katzenstein, D.A.5    Shafer, R.W.6
  • 11
    • 84888014428 scopus 로고    scopus 로고
    • EMEA, EVIPLERA - Summary of Product Characteristics, 2013
    • EMEA, EVIPLERA - Summary of Product Characteristics, 2013. Published Online http://www.ema.europa.eu/docs/en-GB/document-library/EPAR-Product- Information/human/002312/WC500118802.pdf.
  • 13
    • 84884395662 scopus 로고    scopus 로고
    • Prevalence of pre-existing resistance-associated mutations to rilpivirine, emtricitabine and tenofovir in antiretroviral-naive patients infected with B and non-B subtype HIV-1 viruses
    • S. Lambert-Niclot, C. Charpentier, A. Storto, D.B. Fofana, C. Soulie, and S. Fourati Prevalence of pre-existing resistance-associated mutations to rilpivirine, emtricitabine and tenofovir in antiretroviral-naive patients infected with B and non-B subtype HIV-1 viruses J. Antimicrob. Chemother. 68 2013 1237 1242
    • (2013) J. Antimicrob. Chemother. , vol.68 , pp. 1237-1242
    • Lambert-Niclot, S.1    Charpentier, C.2    Storto, A.3    Fofana, D.B.4    Soulie, C.5    Fourati, S.6
  • 14
    • 84888015201 scopus 로고    scopus 로고
    • 96-week resistance analyses of rilpivirine in treatment-naive, HIV-1-infected adults from the ECHO and THRIVE Phase III trials
    • 10.3851/IMP2636 [Epub ahead of print]
    • L. Rimsky, V. Van Eygen, A. Hoogstoel, M. Stevens, K. Boven, and G. Picchio 96-week resistance analyses of rilpivirine in treatment-naive, HIV-1-infected adults from the ECHO and THRIVE Phase III trials Antivir. Ther. 2013 10.3851/IMP2636 [Epub ahead of print]
    • (2013) Antivir. Ther.
    • Rimsky, L.1    Van Eygen, V.2    Hoogstoel, A.3    Stevens, M.4    Boven, K.5    Picchio, G.6
  • 15
    • 84875676262 scopus 로고    scopus 로고
    • Pre-existing mutations in the rilpivirine Phase III trials ECHO and THRIVE: Prevalence and impact on virological response
    • J. Vingerhoets, L. Rimsky, V. Van Eygen, S. Nijs, S. Vanveggel, and K. Boven Pre-existing mutations in the rilpivirine Phase III trials ECHO and THRIVE: prevalence and impact on virological response Antivir. Ther. 18 2013 253 256
    • (2013) Antivir. Ther. , vol.18 , pp. 253-256
    • Vingerhoets, J.1    Rimsky, L.2    Van Eygen, V.3    Nijs, S.4    Vanveggel, S.5    Boven, K.6
  • 16
    • 84876410269 scopus 로고    scopus 로고
    • Distinct resistance patterns to etravirine and rilpivirine in viruses containing nonnucleoside reverse transcriptase inhibitor mutations at baseline
    • E.L. Asahchop, M.A. Wainberg, M. Oliveira, H. Xu, B.G. Brenner, and D. Moisi Distinct resistance patterns to etravirine and rilpivirine in viruses containing nonnucleoside reverse transcriptase inhibitor mutations at baseline AIDS 27 2013 879 887
    • (2013) AIDS , vol.27 , pp. 879-887
    • Asahchop, E.L.1    Wainberg, M.A.2    Oliveira, M.3    Xu, H.4    Brenner, B.G.5    Moisi, D.6
  • 17
    • 83655163698 scopus 로고    scopus 로고
    • Genotypic and phenotypic characterization of HIV-1 isolates obtained from patients on rilpivirine therapy experiencing virologic failure in the phase 3 ECHO and THRIVE studies: 48-week analysis
    • L. Rimsky, J. Vingerhoets, V. Van Eygen, J. Eron, B. Clotet, and A. Hoogstoel Genotypic and phenotypic characterization of HIV-1 isolates obtained from patients on rilpivirine therapy experiencing virologic failure in the phase 3 ECHO and THRIVE studies: 48-week analysis J. Acquir. Immune Defic. Syndr. 59 2012 39 46
    • (2012) J. Acquir. Immune Defic. Syndr. , vol.59 , pp. 39-46
    • Rimsky, L.1    Vingerhoets, J.2    Van Eygen, V.3    Eron, J.4    Clotet, B.5    Hoogstoel, A.6
  • 19
    • 83655201316 scopus 로고    scopus 로고
    • The HIV-1 reverse transcriptase M184I mutation enhances the E138K-associated resistance to rilpivirine and decreases viral fitness
    • R. Kulkarni, K. Babaoglu, E.B. Lansdon, L. Rimsky, V. Van Eygen, and G. Picchio The HIV-1 reverse transcriptase M184I mutation enhances the E138K-associated resistance to rilpivirine and decreases viral fitness J. Acquir. Immune Defic. Syndr. 59 2012 47 54
    • (2012) J. Acquir. Immune Defic. Syndr. , vol.59 , pp. 47-54
    • Kulkarni, R.1    Babaoglu, K.2    Lansdon, E.B.3    Rimsky, L.4    Van Eygen, V.5    Picchio, G.6
  • 20
    • 84879012959 scopus 로고    scopus 로고
    • The effect of mutations at position E138 in HIV-1 reverse transcriptase and their interactions with the M184I mutation in defining patterns of resistance to the non-nucleoside reverse transcriptase inhibitors rilpivirine and etravirine
    • H.T. Xu, S.P. Colby-Germinario, E.L. Asahchop, M. Oliveira, M. McCallum, and S.M. Schader The effect of mutations at position E138 in HIV-1 reverse transcriptase and their interactions with the M184I mutation in defining patterns of resistance to the non-nucleoside reverse transcriptase inhibitors rilpivirine and etravirine Antimicrob. Agents Chemother. 2013
    • (2013) Antimicrob. Agents Chemother.
    • Xu, H.T.1    Colby-Germinario, S.P.2    Asahchop, E.L.3    Oliveira, M.4    McCallum, M.5    Schader, S.M.6
  • 21
    • 84883139732 scopus 로고    scopus 로고
    • Clinical perspective on drugdrug interactions with the non-nucleoside reverse transcriptase inhibitor rilpivirine
    • H. Crauwels, R.P. van Heeswijk, M. Stevens, A. Buelens, S. Vanveggel, and K. Boven Clinical perspective on drugdrug interactions with the non-nucleoside reverse transcriptase inhibitor rilpivirine AIDS Rev. 15 2013 87 101
    • (2013) AIDS Rev. , vol.15 , pp. 87-101
    • Crauwels, H.1    Van Heeswijk, R.P.2    Stevens, M.3    Buelens, A.4    Vanveggel, S.5    Boven, K.6
  • 23
    • 84876406278 scopus 로고    scopus 로고
    • Week 96 efficacy and safety of rilpivirine in treatment-naive, HIV-1 patients in two Phase III randomized trials
    • C.J. Cohen, J.M. Molina, I. Cassetti, P. Chetchotisakd, A. Lazzarin, and C. Orkin Week 96 efficacy and safety of rilpivirine in treatment-naive, HIV-1 patients in two Phase III randomized trials AIDS 27 2013 939 950
    • (2013) AIDS , vol.27 , pp. 939-950
    • Cohen, C.J.1    Molina, J.M.2    Cassetti, I.3    Chetchotisakd, P.4    Lazzarin, A.5    Orkin, C.6
  • 24
    • 84871618383 scopus 로고    scopus 로고
    • Rilpivirine resistance mutations in HIV patients failing non-nucleoside reverse transcriptase inhibitor-based therapies
    • L. Anta, J.M. Llibre, E. Poveda, J.L. Blanco, M. Alvarez, and M.J. Perez-Elias Rilpivirine resistance mutations in HIV patients failing non-nucleoside reverse transcriptase inhibitor-based therapies AIDS 27 2013 81 85
    • (2013) AIDS , vol.27 , pp. 81-85
    • Anta, L.1    Llibre, J.M.2    Poveda, E.3    Blanco, J.L.4    Alvarez, M.5    Perez-Elias, M.J.6
  • 25
    • 80055099715 scopus 로고    scopus 로고
    • Etravirine and rilpivirine resistance in HIV-1 subtype CRF01-AE-infected adults failing non-nucleoside reverse transcriptase inhibitor-based regimens
    • T. Bunupuradah, J. Ananworanich, P. Chetchotisakd, P. Kantipong, S. Jirajariyavej, and S. Sirivichayakul Etravirine and rilpivirine resistance in HIV-1 subtype CRF01-AE-infected adults failing non-nucleoside reverse transcriptase inhibitor-based regimens Antivir. Ther. 16 2011 1113 1120
    • (2011) Antivir. Ther. , vol.16 , pp. 1113-1120
    • Bunupuradah, T.1    Ananworanich, J.2    Chetchotisakd, P.3    Kantipong, P.4    Jirajariyavej, S.5    Sirivichayakul, S.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.