Site-specific aspartic acid isomerization regulates self-assembly and neurotoxicity of amyloid-β

Biochemical and Biophysical Research Communications

Volumn 441, Issue 2, 2013, Pages 493-498

  Sugiki, Toshihiko ^a   Utsunomiya Tate, Naoko ^a,b  

^a MUSASHINO UNIVERSITY   (Japan)

^b TEIKYO UNIVERSITY   (Japan)

Author keywords

A 1 42; Alzheimer's diseases; Amyloid ; Circular dichroism; d Asp isomerization

Indexed keywords

8 ANILINO 1 NAPHTHALENESULFONIC ACID; AMYLOID BETA PROTEIN; AMYLOID BETA PROTEIN[1-42]; ASPARTIC ACID; NERVE GROWTH FACTOR; OLIGOMER;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; BRAIN; CIRCULAR DICHROISM; CROSS LINKING; FLUORESCENCE; ISOMERISM; MEASUREMENT; NEUROTOXICITY; NONHUMAN; PHEOCHROMOCYTOMA CELL; PHOTOCHEMISTRY; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RAT; SENILE PLAQUE; SPECTROSCOPY; WESTERN BLOTTING;

ALZHEIMER DISEASE; AMYLOID; AMYLOID BETA-PEPTIDES; ANIMALS; ASPARTIC ACID; CELL SURVIVAL; DRUG DESIGN; HUMANS; ISOMERISM; NEURONS; PC12 CELLS; PEPTIDE FRAGMENTS; PROTEIN STRUCTURE, SECONDARY; RATS;

EID: 84887997703     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2013.10.084     Document Type: Article

References (27)

1. H. Braak, E. Braak, I. Grundke-Iqbal, and K. Iqbal Occurrence of neuropil threads in the senile human brain and in Alzheimer's disease: a third location of paired helical filaments outside of neurofibrillary tangles and neuritic plaques Neurosci. Lett. 65 1986 351 355
2. V.W. Henderson, and C.E. Finch The neurobiology of Alzheimer's disease J. Neurosurg. 70 1989 335 353
3. A.E. Roher, J.D. Lowenson, S. Clarke, A.S. Woods, R.J. Cotter, E. Gowing, and M.J. Ball β-Amyloid-(1-42) is a major component of cerebrovascular amyloid deposits: implications for the pathology of Alzheimer disease Proc. Natl. Acad. Sci. USA 90 1993 10836 10840
4. J.J. Balbach, A.T. Petkova, N.A. Oyler, O.N. Antzutkin, D.J. Gordon, S.C. Meredith, and R. Tycko Supermolecular structure in full-length Alzheimer's β-amyloid fibrils: evidence for a parallel β-sheet organization from solid-state nuclear magnetic resonance Biophys. J. 83 2002 1205 1216
5. S. Ritz-Timme, and M.J. Collins Racemization of aspartic acid in human protein Ageing Res. Rev. 1 2002 43 59
6. J. Orpiszewski, and M.D. Benson Induction of beta-sheet structure in amyloidogenic peptides by neutralization of aspartate: a model for amyloid nucleation J. Mol. Biol. 289 1999 413 428
7. T. Shimizu, A. Watanabe, M. Ogawara, H. Mori, and T. Shirasawa Isoaspartate formation and neurodegeneration in Alzheimer's disease Arch. Biochem. Biophys. 381 2000 225 234
8. A.E. Roher, J.D. Lowenson, S. Clarke, C. Wolkow, R. Wang, R.J. Cotter, I.M. Reardon, H.A. Zürcher-Neely, R.L. Heinrikson, M.J. Ball, and B.D. Greenberg Structural alterations in the peptide backbone of β-amyloid core protein may account for its deposition and stability in Alzheimer's disease J. Biol. Chem. 268 1993 3072 3083
9. T.J. Grabowski, H.S. Cho, J.P. Vonsattel, G.W. Rebeck, and S.M. Greenberg Novel amyloid precursor protein mutation in an Iowa family with dementia and severe cerebral amyloid angiopathy Ann. Neurol. 49 2001 697 705
10. H. Fukuda, T. Shimizu, M. Nakajima, H. Hori, and T. Shirasawa Synthesis, aggregation, and neurotoxicity of the Alzheimer's Abeta1-42 amyloid peptide and its isoaspartyl isomers Bioorg. Med. Chem. Lett. 9 1999 953 956
11. 23 residue Biochem. Biophys. Res. Commun. 364 2007 464 469
12. N.J. Greenfield Using circular dichroism spectra to estimate protein secondary structure Nat. Protoc. 1 2006 2876 2890
13. J. Reed, and T.A. Reed A set of constructed type spectra for the practical estimation of peptide secondary structure from circular dichroism Anal. Biochem. 254 1997 36 40
14. G. Bitan, A. Lomakin, and D.B. Teplow Amyloid β-protein oligomerization J. Biol. Chem. 14 2001 35176 35184
15. F. Rahimi, P. Malti, and G. Bitan Photo-induced cross-linking of unmodified proteins (PICUP) applied to amyloidogenic peptides J. Vis. Exp. 23 2009 1 3
16. N.E. Pryor, M.A. Moss, and C.N. Hestekin Unraveling the early events of amyloid-β protein (Aβ) aggregation: techniques for the determination of Aβ aggregate size Int. J. Mol. Sci. 13 2012 3038 3072
17. Y. Cordeiro, L.M.T.R. Lima, M.P.B. Gomes, D. Foguel, and J.L. Silva Modulation of prion protein oligomerization, aggregation, and β-sheet conversion by 4,4′-dianilino-1,1′-binaphthyl-5,5′-sulfonate (bis-ANS) J. Biol. Chem. 279 2004 5346 5352
18. A.D. Ferrão-Gonzales, B.K. Robbs, V.H. Moreau, A. Ferreira, L. Juliano, A.P. Valente, F.C.L. Almeida, J.L. Silva, and D. Foguel Controlling β-amyloid oligomerization by the use of naphthalene sulfonates J. Biol. Chem. 280 2006 34747 34754
19. S.G. Bolder, L.M. Sagis, P. Venema, and E. van der Linden Thioflavin T and birefringence assays to determine the conversion of proteins into fibrils Langmuir 23 2007 4144 4147
20. A. Hawe, M. Sutter, and W. Jiskoot Extrinsic fluorescent dyes as tools for protein characterization Pharm. Res. 25 2008 1487 1499
21. M. Bucciantini, G. Calloni, F. Chiti, L. Formigli, D. Nosi, C.M. Dobson, and M. Stefani Prefibrillar amyloid protein aggregates share common features of cytotoxicity J. Biol. Chem. 279 2004 31374 31382
22. A.L. Lublin, and S. Gandy Amyloid-β oligomers: possible roles as key neurotoxins in Alzheimer's disease Mt. Sinai J. Med. 77 2010 43 49
23. M.E. Larson, and S.E. Lesné Soluble Aβ oligomer production and toxicity J. Neurochem. 120 2012 125 139
24. 23 of Aβ42 do not increase its aggregative ability, neurotoxicity, and radical productivity in vitro Biochem. Biophys. Res. Commun. 366 2008 745 751
25. Y. Masuda, K. Irie, K. Murakami, H. Ohigashi, R. Ohashi, K. Takegoshi, T. Shimizu, and T. Shirasawa Verification of the turn at position 22 and 23 of the β-amyloid fibrils with Italian mutation using solid-state NMR Bioorg. Med. Chem. 13 2005 6803 6809
26. P.N. McFandden, and S. Clarke Methylation at d-aspartyl residues in erythrocytes: possible step in the repair of aged membrane proteins Proc. Natl. Acad. Sci. USA 79 1982 2460 2464
27. G. Jung, J. Ryu, J. Heo, S.J. Lee, J.Y. Cho, and S. Hong Protein l-isoaspartyl O-methyltransferase inhibits amyloid beta fibrillogenesis in vitro Pharmazie 66 2011 529 534