Salt loading exacerbates diastolic dysfunction and cardiac remodeling in young female Ren2 rats

Metabolism: Clinical and Experimental

Volumn 62, Issue 12, 2013, Pages 1761-1771

  Whaley Connell, Adam T ^a,b   Habibi, Javad ^a,b   Aroor, Annayya ^a,b   Ma, Lixin ^a,b   Hayden, Melvin R ^a,b   Ferrario, Carlos M ^c   Demarco, Vincent G ^a,b   Sowers, James R ^a,b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b University of Missouri   (United States)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

Author keywords

Angiotensin II; Oxidative stress; Perivascular fibrosis; TG (mRen2) 27 rat

Indexed keywords

3 NITROTYROSINE; ALDOSTERONE; ANGIOTENSIN II; COLLAGEN TYPE 1; INSULIN; RENIN; SODIUM CHLORIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BIOGENESIS; CONTROLLED STUDY; DIASTOLIC DYSFUNCTION; DIET; DISEASE EXACERBATION; FEMALE; HEART FUNCTION; HEART HYPERTROPHY; HEART LEFT VENTRICLE PRESSURE; HEART MITOCHONDRION; HEART MUSCLE CELL; HEART MUSCLE FIBROSIS; HEMODYNAMIC PARAMETERS; INSULIN RESISTANCE; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; RAT; SALT INTAKE; SALT LOADING; SYSTOLIC BLOOD PRESSURE;

3-NITROTYROSINE; 3-NT; ANG II; ANGIOTENSIN II; BODY WEIGHT; BW; COX IV; CYTOCHROME OXIDASE IV; DIASTOLIC RELAXATION TIME; DRT; HEART RATE; HR; IFR; INITIAL FILING RATE; LEFT VENTRICULAR; LEFT VENTRICULAR HYPERTROPHY; LEFT VENTRICULAR VOLUME; LV; LVH; LVV; MAGNETIC RESONANCE IMAGING; MINERALOCORTICOID RECEPTOR; MR; MRI; OXIDATIVE STRESS; PERIVASCULAR FIBROSIS; QUANTITATIVE INSULIN SENSITIVITY CHECK INDEX; QUICKI; RAAS; REN2; REN2 4% SALT; REN2-HS; RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM; S; SBP; SD; SEPTAL; SPRAGUE-DAWLEY; SYSTOLIC BLOOD PRESSURE; TEM; TG (MREN2) 27 RAT; TRANSGENIC (MREN2)27; TRANSMISSION ELECTRON MICROSCOPY;

ANIMALS; COLLAGEN; FEMALE; FIBROSIS; FLUORESCENT ANTIBODY TECHNIQUE; HEART FAILURE, DIASTOLIC; HEMODYNAMICS; HYPERTROPHY, LEFT VENTRICULAR; MAGNETIC RESONANCE IMAGING; MICROSCOPY, ELECTRON, TRANSMISSION; MITOCHONDRIA, HEART; MYOCARDIUM; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; RATS, TRANSGENIC; SODIUM, DIETARY; TYROSINE; VENTRICULAR FUNCTION, LEFT;

EID: 84887992725     PISSN: 00260495     EISSN: 15328600     Source Type: Journal    
DOI: 10.1016/j.metabol.2013.08.010     Document Type: Article

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