Aberration in epigenetic gene regulation in hippocampal neurogenesis by developmental exposure to manganese chloride in mice

Toxicological Sciences

Volumn 136, Issue 1, 2013, Pages 154-165

  Wang, Liyun ^a   Shiraki, Ayako ^a,b   Itahashi, Megu ^a,b   Akane, Hirotoshi ^a   Abe, Hajime ^a,b   Mitsumori, Kunitoshi ^a,c   Shibutani, Makoto ^a  

^a TOKYO UNIVERSITY OF AGRICULTURE AND TECHNOLOGY   (Japan)

^b GIFU UNIVERSITY   (Japan)

^c Food Safety Commission of Japan   (Japan)

Author keywords

Epigenetic gene regulation; Hippocampal dentate gyrus; Manganese; Neurodevelopment; Neurogenesis; Subgranular zone.

Indexed keywords

4 AMINOBUTYRIC ACID; ACTIN LIKE 6B; ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM) ALPHA 3; CGG TRIPLET REPEAT BINDING PROTEIN 1; CHICKEN OVALBUMIN UPSTREAM PROMOTER TRANSCRIPTION FACTOR 1; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HOMEOBOX C8; HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE; MANGANESE CHLORIDE; MESSENGER RNA; PARVALBUMIN; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CELL LINEAGE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CPG ISLAND; DENTATE GYRUS; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; FEMALE; GENE CONTROL; GESTATIONAL AGE; GRANULE CELL; IMMUNOREACTIVITY; INTERNEURON; MALE; MATERNAL NUTRITION; MICROARRAY ANALYSIS; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; PERINATAL PERIOD; PRENATAL DRUG EXPOSURE; PROMOTER REGION; WEANING;

EPIGENETIC GENE REGULATION; HIPPOCAMPAL DENTATE GYRUS; MANGANESE; NEURODEVELOPMENT; NEUROGENESIS; SUBGRANULAR ZONE.;

AGE FACTORS; ANIMALS; ANIMALS, NEWBORN; CHLORIDES; COUP TRANSCRIPTION FACTOR I; CPG ISLANDS; DENTATE GYRUS; DNA METHYLATION; DOSE-RESPONSE RELATIONSHIP, DRUG; EPIGENESIS, GENETIC; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GESTATIONAL AGE; MALE; MANGANESE COMPOUNDS; MANGANESE POISONING; MATERNAL EXPOSURE; MICE; MICE, INBRED ICR; NEUROGENESIS; NEURONS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PARVALBUMINS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROMOTER REGIONS, GENETIC; PROTEINS; REPRODUCIBILITY OF RESULTS; RNA, MESSENGER; SODIUM-POTASSIUM-EXCHANGING ATPASE; WEANING;

EID: 84887967676     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kft183     Document Type: Article

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