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Volumn 56, Issue 21, 2013, Pages 8298-8307

Design, synthesis, and biological evaluation of novel investigational nonapeptide KISS1R agonists with testosterone-suppressive activity

Author keywords

[No Author keywords available]

Indexed keywords

KISSPEPTIN; LEUPRORELIN; METASTIN; NONAPEPTIDE; RECOMBINANT CHORIONIC GONADOTROPIN; TAK 448; TAK 683; TESTOSTERONE; UNCLASSIFIED DRUG;

EID: 84887944417     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm401056w     Document Type: Article
Times cited : (38)

References (17)
  • 5
    • 2942750179 scopus 로고    scopus 로고
    • Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat
    • Matsui, H.; Takatsu, Y.; Kumano, S.; Matsumoto, H.; Ohtaki, T. Peripheral administration of metastin induces marked gonadotropin release and ovulation in the rat Biochem. Biophys. Res. Commun. 2004, 320, 383-388
    • (2004) Biochem. Biophys. Res. Commun. , vol.320 , pp. 383-388
    • Matsui, H.1    Takatsu, Y.2    Kumano, S.3    Matsumoto, H.4    Ohtaki, T.5
  • 9
    • 0022338092 scopus 로고
    • Leuprolide for prostate cancer
    • Leuprolide for prostate cancer. Med. Lett. Drugs Ther. 1985, 27, 71-72.
    • (1985) Med. Lett. Drugs Ther. , vol.27 , pp. 71-72
  • 13
    • 0014819315 scopus 로고
    • Controlled deamidation of peptides and proteins: An experimental hazard and a possible biological timer
    • Robinson, A. B.; McKerrow, J. H.; Cary, P. Controlled deamidation of peptides and proteins: An experimental hazard and a possible biological timer Proc. Natl. Acad. Sci. U.S.A. 1970, 66, 753-757
    • (1970) Proc. Natl. Acad. Sci. U.S.A. , vol.66 , pp. 753-757
    • Robinson, A.B.1    McKerrow, J.H.2    Cary, P.3
  • 15
    • 33645884139 scopus 로고    scopus 로고
    • Continuous human metastin 45-54 infusion desensitizes G protein-coupled receptor 54-induced gonadotropin-releasing hormone release monitored indirectly in the juvenile male Rhesus monkey (Macaca mulatta): A finding with therapeutic implications
    • Seminara, S. B.; Dipietro, M. J.; Ramaswamy, S.; Crowley, W. F., Jr.; Plant, T. M. Continuous human metastin 45-54 infusion desensitizes G protein-coupled receptor 54-induced gonadotropin-releasing hormone release monitored indirectly in the juvenile male Rhesus monkey (Macaca mulatta): A finding with therapeutic implications Endocrinology 2006, 147, 2122-2126
    • (2006) Endocrinology , vol.147 , pp. 2122-2126
    • Seminara, S.B.1    Dipietro, M.J.2    Ramaswamy, S.3    Crowley Jr., W.F.4    Plant, T.M.5
  • 17
    • 84867811973 scopus 로고    scopus 로고
    • Chronic administration of the metastin/kisspeptin analog KISS1-305 or the investigational agent TAK-448 suppresses hypothalamic pituitary gonadal function and depletes plasma testosterone in adult male rats
    • Matsui, H.; Tanaka, A.; Yokoyama, K.; Takatsu, Y.; Ishikawa, K.; Asami, T.; Nishizawa, N.; Suzuki, A.; Kumano, S.; Terada, M.; Kusaka, M.; Kitada, C.; Ohtaki, T. Chronic administration of the metastin/kisspeptin analog KISS1-305 or the investigational agent TAK-448 suppresses hypothalamic pituitary gonadal function and depletes plasma testosterone in adult male rats Endocrinology 2012, 153, 5297-308
    • (2012) Endocrinology , vol.153 , pp. 5297-5308
    • Matsui, H.1    Tanaka, A.2    Yokoyama, K.3    Takatsu, Y.4    Ishikawa, K.5    Asami, T.6    Nishizawa, N.7    Suzuki, A.8    Kumano, S.9    Terada, M.10    Kusaka, M.11    Kitada, C.12    Ohtaki, T.13


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.