Serum stability of selected decapeptide agonists of KISS1R using pseudopeptides

Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 20, 2012, Pages 6391-6396

  Asami, Taiji ^a   Nishizawa, Naoki ^a   Ishibashi, Yoshihiro ^a   Nishibori, Kimiko ^a   Nakayama, Masaharu ^a   Horikoshi, Yasuko ^a   Matsumoto, Shin Ichi ^a   Yamaguchi, Masashi ^a   Matsumoto, Hirokazu ^a   Tarui, Naoki ^a   Ohtaki, Tetsuya ^a   Kitada, Chieko ^a  

^a TAKEDA PHARMACEUTICAL COMPANY LIMITED   (Japan)

Author keywords

KISS1R agonist; Kisspeptin; Metastin; Metastin analog; Metastin(45 54); Serum stability

Indexed keywords

G PROTEIN COUPLED RECEPTOR 54; GLYCINE; KISS1 RECEPTOR AGONIST; LEUCINE; METASTIN; PHENYLALANINE; PSEUDOPEPTIDE; SERINE; THREONINE; TRYPTOPHAN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; DRUG RECEPTOR BINDING; DRUG STABILITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; MOUSE; NONHUMAN; RAT; REACTION ANALYSIS; RECEPTOR AFFINITY; SEQUENCE ANALYSIS; SERUM; STRUCTURE ANALYSIS;

ALANINE; AMINO ACID SEQUENCE; AMINO ACIDS; ANIMALS; GLYCINE; HUMANS; KISSPEPTINS; MICE; RECEPTORS, G-PROTEIN-COUPLED; SERUM; TRYPTOPHAN;

EID: 84866741893     PISSN: 0960894X     EISSN: 14643405     Source Type: Journal    
DOI: 10.1016/j.bmcl.2012.08.069     Document Type: Article

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