Population pharmacokinetics of tranexamic acid in adults undergoing cardiac surgery with cardiopulmonary bypass

British Journal of Anaesthesia

Volumn 111, Issue 6, 2013, Pages 916-924

  Grassin Delyle, S ^a,c   Tremey, B ^b   Abe, E ^c   Fischler, M ^b,d   Alvarez, J C ^c,d   Devillier, P ^a,d   Urien, S ^e,f  

^a UPRES EA 220   (France)

^b FOCH HOSPITAL   (France)

^c RAYMOND POINCARÉ HOSPITAL   (France)

^d LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

^e ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^f UNIVERSITÉ PARIS DESCARTES   (France)

Author keywords

Cardiopulmonary bypass; Cardiovascular surgical procedures; Pharmacokinetics; Tranexamic acid

Indexed keywords

TRANEXAMIC ACID;

ADULT; AGED; ARTICLE; CARDIOPULMONARY BYPASS; CONTINUOUS INFUSION; CONTROLLED STUDY; DOSE RESPONSE; DOUBLE BLIND PROCEDURE; DRUG BLOOD LEVEL; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG MEGADOSE; FEMALE; FIBRINOLYSIS; HEART SURGERY; HEMOSTASIS; HUMAN; HUMAN TISSUE; LOW DRUG DOSE; MAJOR CLINICAL STUDY; MALE; PEROPERATIVE CARE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; THROMBOCYTE COUNT;

EID: 84887935146     PISSN: 00070912     EISSN: 14716771     Source Type: Journal    
DOI: 10.1093/bja/aet255     Document Type: Article

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