IGF-1-mediated osteoblastic niche expansion enhances long-term hematopoietic stem cell engraftment after murine bone marrow transplantation

Stem Cells

Volumn 31, Issue 10, 2013, Pages 2193-2204

  Caselli, Anna ^a,b   Olson, Timothy S ^b   Otsuru, Satoru ^b   Chen, Xiaohua ^b   Hofmann, Ted J ^b   Nah, Hyun Duck ^c   Grisendi, Giulia ^a   Paolucci, Paolo ^a   Dominici, Massimo ^a   Horwitz, Edwin M ^b  

^a UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c CHILDREN S HOSPITAL OF PHILADELPHIA   (United States)

Author keywords

Insulin like growth factor 1; Mouse; Niche; Osteoblasts; Stem cell transplantation

Indexed keywords

FIBROBLAST GROWTH FACTOR 2; GREEN FLUORESCENT PROTEIN; OSTEOCALCIN; PLATELET DERIVED GROWTH FACTOR BB; SOMATOMEDIN C; STROMAL CELL DERIVED FACTOR 1; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL BEHAVIOR; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BONE MARROW TRANSPLANTATION; CELL CULTURE; CELL EXPANSION; CELL GROWTH; CELL MATURATION; CELL PROLIFERATION; CELL TYPE; COLONY FORMATION; CONTROLLED STUDY; ENDOSTEUM; ENGRAFTMENT; GENE EXPRESSION; HEMATOPOIETIC CELL; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HISTOLOGY; IMMUNOHISTOCHEMISTRY; MICROENVIRONMENT; MOUSE; NONHUMAN; ORGAN DONOR; OSTEOBLAST; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; STEM CELL NICHE; TRABECULAR BONE; WHOLE BODY RADIATION;

INSULIN-LIKE GROWTH FACTOR 1; MOUSE; NICHE; OSTEOBLASTS; STEM CELL TRANSPLANTATION;

ANIMALS; BONE AND BONES; BONE MARROW TRANSPLANTATION; CELL MOVEMENT; CELL PROLIFERATION; GRAFT SURVIVAL; HEMATOPOIESIS; HEMATOPOIETIC STEM CELL TRANSPLANTATION; INSULIN-LIKE GROWTH FACTOR I; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OSTEOBLASTS; STEM CELL NICHE; WHOLE-BODY IRRADIATION;

EID: 84887895256     PISSN: 10665099     EISSN: None     Source Type: Journal    
DOI: 10.1002/stem.1463     Document Type: Article

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