메뉴 건너뛰기




Volumn 20, Issue SUPPL.1, 2014, Pages

Quantification of α-synuclein in cerebrospinal fluid: How ideal is this biomarker for Parkinson's disease?

Author keywords

Synuclein; Biomarker; Cerebrospinal fluid; Parkinson's disease

Indexed keywords

ALPHA SYNUCLEIN; BIOLOGICAL MARKER;

EID: 84887862096     PISSN: 13538020     EISSN: 18735126     Source Type: Journal    
DOI: 10.1016/S1353-8020(13)70020-8     Document Type: Article
Times cited : (41)

References (30)
  • 1
    • 19944433460 scopus 로고    scopus 로고
    • A responsive outcome for Parkinson's disease neuroprotection futility studies
    • Elm JJ, Goetz CG, Ravina B, Shannon K, Wooten GF, Tanner CM, et al. A responsive outcome for Parkinson's disease neuroprotection futility studies. Ann Neurol 2005, 57:197-203.
    • (2005) Ann Neurol , vol.57 , pp. 197-203
    • Elm, J.J.1    Goetz, C.G.2    Ravina, B.3    Shannon, K.4    Wooten, G.F.5    Tanner, C.M.6
  • 3
    • 0034531475 scopus 로고    scopus 로고
    • The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy
    • Spillantini MG, Goedert M The alpha-synucleinopathies: Parkinson's disease, dementia with Lewy bodies, and multiple system atrophy. Ann N Y Acad Sci 2000, 920:16-27.
    • (2000) Ann N Y Acad Sci , vol.920 , pp. 16-27
    • Spillantini, M.G.1    Goedert, M.2
  • 4
    • 33645116252 scopus 로고    scopus 로고
    • Genetics of Parkinson disease: paradigm shifts and future prospects
    • Farrer MJ Genetics of Parkinson disease: paradigm shifts and future prospects. Nat Rev Genet 2006, 7:306-318.
    • (2006) Nat Rev Genet , vol.7 , pp. 306-318
    • Farrer, M.J.1
  • 5
    • 77958065285 scopus 로고    scopus 로고
    • Quantification of alpha-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies
    • Mollenhauer B, El-Agnaf OM, Marcus K, Trenkwalder C, Schlossmacher MG Quantification of alpha-synuclein in cerebrospinal fluid as a biomarker candidate: review of the literature and considerations for future studies. Biomark Med 2010, 4:683-699.
    • (2010) Biomark Med , vol.4 , pp. 683-699
    • Mollenhauer, B.1    El-Agnaf, O.M.2    Marcus, K.3    Trenkwalder, C.4    Schlossmacher, M.G.5
  • 6
    • 0032093211 scopus 로고    scopus 로고
    • A new consensus report on biomarkers for the early antemortem diagnosis of Alzheimer disease: current status, relevance to drug discovery, and recommendations for future research
    • Trojanowski JQ, Growdon JH A new consensus report on biomarkers for the early antemortem diagnosis of Alzheimer disease: current status, relevance to drug discovery, and recommendations for future research. J Neuropathol Exp Neurol 1998, 57:643-644.
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 643-644
    • Trojanowski, J.Q.1    Growdon, J.H.2
  • 7
    • 33644832047 scopus 로고    scopus 로고
    • Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans
    • Fagan AM, Mintun MA, Mach RH, Lee SY, Dence CS, Shah AR, et al. Inverse relation between in vivo amyloid imaging load and cerebrospinal fluid Abeta42 in humans. Ann Neurol 2006, 59:512-519.
    • (2006) Ann Neurol , vol.59 , pp. 512-519
    • Fagan, A.M.1    Mintun, M.A.2    Mach, R.H.3    Lee, S.Y.4    Dence, C.S.5    Shah, A.R.6
  • 8
    • 33144489150 scopus 로고    scopus 로고
    • Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium
    • McKeith IG, Dickson DW, Lowe J, Emre M, O'Brien JT, Feldman H, et al. Diagnosis and management of dementia with Lewy bodies: Third report of the DLB consortium. Neurology 2005, 65:1863-1872.
    • (2005) Neurology , vol.65 , pp. 1863-1872
    • McKeith, I.G.1    Dickson, D.W.2    Lowe, J.3    Emre, M.4    O'Brien, J.T.5    Feldman, H.6
  • 9
  • 10
    • 84871285797 scopus 로고    scopus 로고
    • Neurodegeneration in Parkinson disease: moving Lewy bodies out of focus
    • Schulz-Schaeffer WJ Neurodegeneration in Parkinson disease: moving Lewy bodies out of focus. Neurology 2012, 79:2298-2299.
    • (2012) Neurology , vol.79 , pp. 2298-2299
    • Schulz-Schaeffer, W.J.1
  • 12
    • 77950223687 scopus 로고    scopus 로고
    • DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease
    • Hong Z, Shi M, Chung KA, Quinn JF, Peskind ER, Galasko D, et al. DJ-1 and alpha-synuclein in human cerebrospinal fluid as biomarkers of Parkinson's disease. Brain 2010, 133:713-726.
    • (2010) Brain , vol.133 , pp. 713-726
    • Hong, Z.1    Shi, M.2    Chung, K.A.3    Quinn, J.F.4    Peskind, E.R.5    Galasko, D.6
  • 13
    • 0026514953 scopus 로고
    • Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases
    • Hughes AJ, Daniel SE, Kilford L, Lees AJ Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. J Neurol Neurosurg Psychiatry 1992, 55:181-184.
    • (1992) J Neurol Neurosurg Psychiatry , vol.55 , pp. 181-184
    • Hughes, A.J.1    Daniel, S.E.2    Kilford, L.3    Lees, A.J.4
  • 14
    • 84885699313 scopus 로고    scopus 로고
    • Association of cerebrospinal fluid beta-amyloid 1-42, T-tau, P-tau181, and alpha-synuclein levels with clinical features of drug-naive patients with early Parkinson disease
    • [Epub ahead of print].
    • Kang JH, Irwin DJ, Chen-Plotkin AS, Siderowf A, Caspell C, Coffey CS, et al. Association of cerebrospinal fluid beta-amyloid 1-42, T-tau, P-tau181, and alpha-synuclein levels with clinical features of drug-naive patients with early Parkinson disease. JAMA Neurol 2013 Aug 26, [Epub ahead of print].
    • (2013) JAMA Neurol A 26
    • Kang, J.H.1    Irwin, D.J.2    Chen-Plotkin, A.S.3    Siderowf, A.4    Caspell, C.5    Coffey, C.S.6
  • 15
    • 84868585835 scopus 로고    scopus 로고
    • Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders
    • Hall S, Öhrfelt A, Constantinescu R, Andreasson U, Surova Y, Bostrom F, et al. Accuracy of a panel of 5 cerebrospinal fluid biomarkers in the differential diagnosis of patients with dementia and/or parkinsonian disorders. Arch Neurol 2012, 69:1445-1452.
    • (2012) Arch Neurol , vol.69 , pp. 1445-1452
    • Hall, S.1    Öhrfelt, A.2    Constantinescu, R.3    Andreasson, U.4    Surova, Y.5    Bostrom, F.6
  • 17
    • 79960613150 scopus 로고    scopus 로고
    • Cerebrospinal fluid Tau/alpha-synuclein ratio in Parkinson's disease and degenerative dementias
    • Parnetti L, Chiasserini D, Bellomo G, Giannandrea D, De Carlo C, Qureshi MM, et al. Cerebrospinal fluid Tau/alpha-synuclein ratio in Parkinson's disease and degenerative dementias. Mov Disord 2011, 26:1428-1435.
    • (2011) Mov Disord , vol.26 , pp. 1428-1435
    • Parnetti, L.1    Chiasserini, D.2    Bellomo, G.3    Giannandrea, D.4    De Carlo, C.5    Qureshi, M.M.6
  • 18
    • 84890574796 scopus 로고    scopus 로고
    • Alpha-synuclein post-translational modifications as potential biomarkers for Parkinson's disease and other synucleinopathies
    • [Epub ahead of print].
    • Schmid AW, Fauvet B, Moniatte M, Lashuel HA Alpha-synuclein post-translational modifications as potential biomarkers for Parkinson's disease and other synucleinopathies. Mol Cell Proteomics 2013 Aug 23, [Epub ahead of print].
    • (2013) Mol Cell Proteomics A 23
    • Schmid, A.W.1    Fauvet, B.2    Moniatte, M.3    Lashuel, H.A.4
  • 19
    • 49449105990 scopus 로고    scopus 로고
    • Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration
    • Mollenhauer B, Cullen V, Kahn I, Krastins B, Outeiro TF, Pepivani I, et al. Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration. Exp Neurol 2008, 213:315-325.
    • (2008) Exp Neurol , vol.213 , pp. 315-325
    • Mollenhauer, B.1    Cullen, V.2    Kahn, I.3    Krastins, B.4    Outeiro, T.F.5    Pepivani, I.6
  • 20
    • 84863425120 scopus 로고    scopus 로고
    • α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system
    • Mollenhauer B, Trautmann E, Otte B, Ng J, Spreer A, Lange P, et al. α-Synuclein in human cerebrospinal fluid is principally derived from neurons of the central nervous system. J Neural Transm 2012, 119:739-746.
    • (2012) J Neural Transm , vol.119 , pp. 739-746
    • Mollenhauer, B.1    Trautmann, E.2    Otte, B.3    Ng, J.4    Spreer, A.5    Lange, P.6
  • 22
    • 81855190652 scopus 로고    scopus 로고
    • Salivary tau species are potential biomarkers of Alzheimer's disease
    • Shi M, Sui YT, Peskind ER, Li GG, Hwang H, Devic I, et al. Salivary tau species are potential biomarkers of Alzheimer's disease. J Alzheimers Dis 2011, 27(2):299-305.
    • (2011) J Alzheimers Dis , vol.27 , Issue.2 , pp. 299-305
    • Shi, M.1    Sui, Y.T.2    Peskind, E.R.3    Li, G.G.4    Hwang, H.5    Devic, I.6
  • 23
    • 79958233724 scopus 로고    scopus 로고
    • Salivary alpha-synuclein and DJ-1: potential biomarkers for Parkinson's disease
    • Devic I, Hwang H, Edgar JS, Izutsu K, Presland R, Pan C, et al. Salivary alpha-synuclein and DJ-1: potential biomarkers for Parkinson's disease. Brain 2011, 134:e178.
    • (2011) Brain , vol.134
    • Devic, I.1    Hwang, H.2    Edgar, J.S.3    Izutsu, K.4    Presland, R.5    Pan, C.6
  • 24
    • 49449102642 scopus 로고    scopus 로고
    • GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein
    • Scherzer CR, Grass JA, Liao Z, Pepivani I, Zheng B, Eklund AC, et al. GATA transcription factors directly regulate the Parkinson's disease-linked gene alpha-synuclein. Proc Natl Acad Sci U S A 2008, 105:10907-10912.
    • (2008) Proc Natl Acad Sci U S A , vol.105 , pp. 10907-10912
    • Scherzer, C.R.1    Grass, J.A.2    Liao, Z.3    Pepivani, I.4    Zheng, B.5    Eklund, A.C.6
  • 25
    • 77953022918 scopus 로고    scopus 로고
    • Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson's disease
    • Del Tredici K, Hawkes CH, Ghebremedhin E, Braak H Lewy pathology in the submandibular gland of individuals with incidental Lewy body disease and sporadic Parkinson's disease. Acta Neuropathol 2010, 119:703-713.
    • (2010) Acta Neuropathol , vol.119 , pp. 703-713
    • Del Tredici, K.1    Hawkes, C.H.2    Ghebremedhin, E.3    Braak, H.4
  • 26
    • 83455217978 scopus 로고    scopus 로고
    • Plasma and urinary HPLC-ED determination of the ratio of 8-OHdG/2-dG in Parkinson's disease
    • Bolner A, Pilleri M, De Riva V, Nordera GP Plasma and urinary HPLC-ED determination of the ratio of 8-OHdG/2-dG in Parkinson's disease. Clin Lab 2011, 57:859-866.
    • (2011) Clin Lab , vol.57 , pp. 859-866
    • Bolner, A.1    Pilleri, M.2    De Riva, V.3    Nordera, G.P.4
  • 27
    • 77952477706 scopus 로고    scopus 로고
    • Inter-laboratory variation in cerebrospinal fluid biomarkers for Alzheimer's disease: united we stand, divided we fall
    • Mattsson N, Blennow K, Zetterberg H Inter-laboratory variation in cerebrospinal fluid biomarkers for Alzheimer's disease: united we stand, divided we fall. Clin Chem Lab Med 2010, 48:603-607.
    • (2010) Clin Chem Lab Med , vol.48 , pp. 603-607
    • Mattsson, N.1    Blennow, K.2    Zetterberg, H.3
  • 29
    • 84856970318 scopus 로고    scopus 로고
    • DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function
    • Shi M, Furay AR, Sossi V, Aasly JO, Armaly J, Wang Y, et al. DJ-1 and αSYN in LRRK2 CSF do not correlate with striatal dopaminergic function. Neurobiol Aging 2012, 33:836.e5-836.e7.
    • (2012) Neurobiol Aging , vol.33
    • Shi, M.1    Furay, A.R.2    Sossi, V.3    Aasly, J.O.4    Armaly, J.5    Wang, Y.6
  • 30


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.