Menadione (vitamin K3) is a catabolic product of oral phylloquinone (vitamin K1) in the intestine and a circulating precursor of tissue menaquinone-4 (vitamin K2) in rats

Journal of Biological Chemistry

Volumn 288, Issue 46, 2013, Pages 33071-33080

  Hirota, Yoshihisa ^a   Tsugawa, Naoko ^a   Nakagawa, Kimie ^a   Suhara, Yoshitomo ^a   Tanaka, Kiyoshi ^b   Uchino, Yuri ^a   Takeuchi, Atsuko ^c   Sawada, Natsumi ^a   Kamao, Maya ^a   Wada, Akimori ^a   Okitsu, Takashi ^a   Okano, Toshio ^a  

^a KOBE PHARMACEUTICAL UNIVERSITY   (Japan)

^b SHIBAURA INSTITUTE OF TECHNOLOGY   (Japan)

^c KYOTO WOMEN'S UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CATABOLIC PRODUCTS; CLEAVAGE ACTIVITIES; HIGH RESOLUTION; MEASUREMENTS OF; PRENYLTRANSFERASE; PRENYLTRANSFERASE ENZYMES; STABLE ISOTOPE TRACERS; STRUCTURAL ASSIGNMENTS;

BIOASSAY; HISTOLOGY; ISOTOPES; KETONES; RATS; RECOMBINANT PROTEINS; TRACE ANALYSIS;

TISSUE;

DIMETHYLALLYLTRANSFERASE; EPOXIDE; MENADIONE; MENATETRENONE; PHYTOMENADIONE; UBIA PRENYLTRANSFERASE DOMAIN CONTAINING 1; UNCLASSIFIED DRUG; DRUG DERIVATIVE; ENZYME; FARNOQUINONE; RECOMBINANT PROTEIN; VITAMIN; VITAMIN K GROUP;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BIOASSAY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; EXPERIMENTAL ANIMAL; FEMALE; INTESTINE ABSORPTION; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; PRENYLATION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STRUCTURE ANALYSIS; TISSUE DISTRIBUTION; ANIMAL; CONVERSION; GENETICS; INTESTINE; MENAQUINONE-4; METABOLISM; SPECIES DIFFERENCE; SPRAGUE DAWLEY RAT; UBIAD1; ANALOGS AND DERIVATIVES;

CONVERSION; ENZYMES; INTESTINE; MENADIONE; MENAQUINONE-4; METABOLISM; PHYLLOQUINONE; RAT; UBIAD1; VITAMIN K;

ANIMALS; DIMETHYLALLYLTRANSTRANSFERASE; FEMALE; INTESTINES; MALE; MICE; RATS; RATS, SPRAGUE-DAWLEY; RECOMBINANT PROTEINS; SPECIES SPECIFICITY; VITAMIN K 1; VITAMIN K 2; VITAMIN K 3; VITAMINS;

EID: 84887850766     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M113.477356     Document Type: Article

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