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Volumn 18, Issue 9, 2010, Pages 3116-3124
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Structure-activity relationships in the conversion of vitamin K analogues into menaquinone-4. Substrates essential to the synthesis of menaquinone-4 in cultured human cell lines
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Author keywords
Analogues; Conversion; Deuterated compound; Menaquinone 4; Structure activity relationships; Vitamin K
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Indexed keywords
12 IODO 2,6,10 TRIMETHYLDODEC 2 ENE;
12 IODO 2,6,10 TRIMETHYLDODECA 2,6 DIEN;
2',3' PHYTOMENADIONE;
3,7,11 TRIMETHYLDODECA 10 EN 1 OL;
3,7,11 TRIMETHYLDODECA 2,10 DIEN 1 OL;
3,7,11 TRIMETHYLDODECA 6,10 DIEN 1 OL;
3,7,11,15 TETRAMETHYLHEXADECA 2,10,14 TRIEN 1 OL;
3,7,11,15 TETRAMETHYLHEXADECA 2,10,14 TRIENOATE;
3,7,11,15 TETRAMETHYLHEXADECA 2,14 DIEN 1 OL;
3,7,11,15 TETRAMETHYLHEXADECA 2,4 DIENOATE;
6',7' DIHYDROMENATETRENONE;
6',7',10',11' TETRAHYDROMENATETRENONE;
6,10 DIMETHYLUNDEC 9 EN 2 ONE;
6,10,14 TRIMETHYLPENTADEC 13 EN 2 ONE;
6,10,14 TRIMETHYLPENTADECA 9,3 DIEN 2 ONE;
8 IODO 2,6 DIMETHYLOCT 2 ENE;
FARNESOL;
FARNOQUINONE;
GERANIOL;
GERANYLGERANIOL;
HYDROQUINONE;
ISOPRENE;
MENAQUINONE;
MENATETRENONE;
MENATETRENONE EPOXIDE;
NAPHTHOQUINONE;
PHYTOL;
PHYTOMENADIONE;
UNCLASSIFIED DRUG;
VITAMIN K GROUP;
ARTICLE;
CELL CULTURE;
CHEMICAL BOND;
CONTROLLED STUDY;
DRUG STRUCTURE;
DRUG SYNTHESIS;
HIGH PERFORMANCE LIQUID CHROMATOGRAPHY;
HUMAN;
HUMAN CELL;
IN VITRO STUDY;
LIQUID CHROMATOGRAPHY;
PROTON NUCLEAR MAGNETIC RESONANCE;
STRUCTURE ACTIVITY RELATION;
TANDEM MASS SPECTROMETRY;
CELL LINE;
CELL LINE, TUMOR;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
HEMOSTATICS;
HUMANS;
MASS SPECTROMETRY;
MOLECULAR STRUCTURE;
STRUCTURE-ACTIVITY RELATIONSHIP;
SUBSTRATE SPECIFICITY;
VITAMIN K;
VITAMIN K 2;
ANIMALIA;
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EID: 77951205332
PISSN: 09680896
EISSN: None
Source Type: Journal
DOI: 10.1016/j.bmc.2010.03.035 Document Type: Article |
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Times cited : (19)
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References (21)
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