Synthesis and characterization of a pH- and enzyme-sensitive poly(ethylene glycol)-hyaluronic acid-melphalan prodrug

Journal of Bioactive and Compatible Polymers

Volumn 28, Issue 6, 2013, Pages 527-539

  Zhang, Xi ^a   Xu, Haixing ^a,b   Newaz, Zubad ^b   Zhang, Yu ^a   Liu, Ming ^a   Huang, Zhijun ^a   Liu, Hui ^a   Niu, Xiaoqian ^a   Wang, Jianping ^c   Xu, Peihu ^a  

^a WUHAN UNIVERSITY OF TECHNOLOGY   (China)

^b UNIVERSITY OF MICHIGAN   (United States)

^c HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (China)

Author keywords

enzyme sensitive; hyaluronic acid; melphalan; pH sensitive; poly(ethylene glycol); Prodrugs

Indexed keywords

CONTROLLED RELEASE PROPERTIES; FOURIER TRANSFORM INFRA REDS; MELPHALAN; PH SENSITIVE; PHYSICOCHEMICAL PROPERTY; PRODRUGS; PROTON NUCLEAR MAGNETIC RESONANCE; SYNTHESIS AND CHARACTERIZATIONS;

CELL CULTURE; DRUG DELIVERY; DRUG PRODUCTS; ENZYMES; ORGANIC ACIDS; POLYETHYLENE GLYCOLS; SYNTHESIS (CHEMICAL); TRANSMISSION ELECTRON MICROSCOPY; ULTRAVIOLET VISIBLE SPECTROSCOPY;

HYALURONIC ACID;

CYANAMIDE; HYALURONIC ACID; MACROGOL; MELPHALAN;

ARTICLE; CONTROLLED STUDY; CYTOTOXICITY; DRUG RELEASE; DRUG SYNTHESIS; FIBROBLAST; HUMAN; HUMAN CELL; IN VITRO STUDY; INFRARED SPECTROSCOPY; OVARY TUMOR; PARTICLE SIZE; PH; PHYSICAL CHEMISTRY; PROTON NUCLEAR MAGNETIC RESONANCE;

EID: 84887668640     PISSN: 08839115     EISSN: 15308030     Source Type: Journal    
DOI: 10.1177/0883911513507192     Document Type: Article

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