Cognitive function, drusen, and age-related macular degeneration: A cross-sectional study

Eye (Basingstoke)

Volumn 27, Issue 11, 2013, Pages 1281-1287

  Lindekleiv, H ^a   Erke, M G ^a,b   Bertelsen, G ^a,b   Peto, T ^c   Arntzen, K A ^a,b   Schirmer, H ^a,b   Wilsgaard, T ^a   Mathiesen, E B ^a,b   Njolstad, I ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

AMD; cognitive function; drusen

Indexed keywords

AGED; ARTICLE; CEREBROVASCULAR ACCIDENT; COGNITION; CONTROLLED STUDY; DRUSEN; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MALE; RETINA MACULA AGE RELATED DEGENERATION; VERBAL MEMORY;

ADULT; AGED; AGED, 80 AND OVER; COGNITION; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; MACULAR DEGENERATION; MALE; MIDDLE AGED; NORWAY; PROSPECTIVE STUDIES; RETINAL DRUSEN;

EID: 84887646511     PISSN: 0950222X     EISSN: 14765454     Source Type: Journal    
DOI: 10.1038/eye.2013.181     Document Type: Article

References (18)

1. Klaver CC, Wolfs RC, Vingerling JR, Hofman A, de Jong PT. Age-specific prevalence and causes of blindness and visual impairment in an older population: The Rotterdam Study. Arch Ophthalmologica 1998; 116(5): 653-658.
2. Zweifel SA, Spaide RF, Curcio CA, Malek G, Imamura Y. Reticular pseudodrusen are subretinal drusenoid deposits. Ophthalmology 2010; 117(2): 303-312.
3. Curcio CA, Millican CL, Bailey T, Kruth HS. Accumulation of cholesterol with age in human Bruch's membrane. Inves Ophthalmol Visual Sci 2001; 42(1): 265-274.
4. Booij JC, Baas DC, Beisekeeva J, TGMF Gorgels, Bergen AAB. The dynamic nature of Bruch's membrane. Prog Retin Eye Res 2010; 29(1): 1-18.
5. Baker ML,Wang JJ, Rogers S, Klein R, Kuller LH, Larsen EK et al. Early age-related macular degeneration, cognitive function, and dementia: The Cardiovascular Health Study. Arch Ophthalmol 2009; 127(5): 667-673.
6. Wong TY,KleinR, Nieto FJ, Moraes SA,Mosley TH, Couper DJ et al. Is early age-related maculopathy related to cognitive function? The Atherosclerosis Risk in Communities Study. Am J Ophthalmol 2002; 134(6): 828-835.
7. Pham TQ, Kifley A, Mitchell P, Wang JJ. Relation of age-related macular degeneration and cognitive impairment in an older population. Gerontology 2006; 52(6): 353-358.
8. Klaver CC, Ott A, Hofman A, Assink JJ, Breteler MM, de Jong PT. Is age-related maculopathy associated with Alzheimer's Diseasë The Rotterdam Study. Am J Epidemiol 1999; 150(9): 963-968.
9. Anderson DH, Talaga KC, Rivest AJ, Barron E, Hageman GS, Johnson LV. Characterization of beta amyloid assemblies in drusen: The deposits associated with aging and age-related macular degeneration. Exp Eye Res 2004; 78(2): 243-256.
10. Mullins RF, Russel SR, Anderson DH, Hageman GS. Drusen associated with aging and age-related macular degeneration contain proteins common to extracellular deposits associated with atherosclerosis, elastosis, amyloidosis, and dense deposit disease. FASEB J 2000; 14(7): 835-846.
11. Braak H, Braak E. Neuropathological stageing of Alzheimerrelated changes. Acta Neuropathol 1991; 82(4): 239-259.
12. Jacobsen BK, Eggen AE, Mathiesen EB, Wilsgaard T, Njølstad I. Cohort profile: The Tromso Study. Int J Epidemiol 2012; 41(4): 961-967.
13. Tatemichi TK, Desmond DW, Stern Y, Paik M, Sano M, Bagiella E. Cognitive impairment after stroke: Frequency, patterns, and relationship to functional abilities. J Neurol Neurosurg Psychiatry 1994; 57(2): 202-207.
14. Arntzen KA, Schirmer H, Wilsgaard T, Mathiesen EB. Moderate wine consumption is associated with better cognitive test results: A 7 year follow up of 5033 subjects in the Tromsø Study. Acta Neurol Scand Suppl 2010; 190: 23-29.
15. Bird AC, Bressler NM, Bressler SB, Chisholm IH, Coscas G, Davis MD et al. An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol 1995; 39(5): 367-374.
16. Bertelsen G, Erke MG, von Hanno T, Mathiesen EB, Peto T, Sjölie AK et al. The Tromsø Eye Study: Study design, methodology and results on visual acuity and refractive errors. Acta Ophthalmologica 2012, Epub ahead of print 11 September 2010; doi:10.1111/j.1755-3768.2012.02511.x.
17. Erke MG, Bertelsen G, Peto T, Sjölie AK, Lindekleiv H, Njølstad I. Prevalence of age-related macular degeneration in elderly Caucasians: The Tromsø Eye Study. Ophthalmology 2012; 119(9): 1737-1743.
18. Fabrigoule C, Rouch I, Taberly A, Letenneur L, Commenges D, Mazaux JM et al. Cognitive process in preclinical phase of dementia. Brain 1998; 121(Pt 1): 135-141.