Chronic vasodilation increases renal medullary PDE5A and α-ENaC through independent renin-angiotensin-aldosterone system pathways

American Journal of Physiology - Regulatory Integrative and Comparative Physiology

Volumn 305, Issue 10, 2013, Pages

  West, Crystal A ^a   Shaw, Stefan ^a   Sasser, Jennifer M ^a   Fekete, Andrea ^a,c   Alexander, Tyler ^a   Cunningham Jr , Mark W ^a   Masilamani, Shyama M E ^d   Baylis, Chris ^a,b  

^a UNIVERSITY OF FLORIDA   (United States)

^b UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^c SEMMELWEIS UNIVERSITY   (Hungary)

^d WEST VIRGINIA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Subunit of the epithelial sodium channel; Arterial underfilling; Phosphodiesterase 5A

Indexed keywords

ANGIOTENSIN 1 RECEPTOR; ENALAPRIL; EPITHELIAL SODIUM CHANNEL; LOSARTAN; NIFEDIPINE; PDE5A PROTEIN; PROTEIN; SODIUM NITRITE; SPIRONOLACTONE; UNCLASSIFIED DRUG;

ALPHA CHAIN; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY WEIGHT; CHRONIC VASODILATION; CONTROLLED STUDY; DIET; FEMALE; HEMODYNAMICS; KIDNEY MEDULLA; MEAN ARTERIAL PRESSURE; NONHUMAN; PLASMA VOLUME; PRIORITY JOURNAL; RAT; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; SIGNAL TRANSDUCTION; VASODILATATION; VIRGINITY;

Α-SUBUNIT OF THE EPITHELIAL SODIUM CHANNEL; ARTERIAL UNDERFILLING; PHOSPHODIESTERASE 5A;

ANGIOTENSIN II TYPE 1 RECEPTOR BLOCKERS; ANGIOTENSIN-CONVERTING ENZYME INHIBITORS; ANIMALS; BLOOD PRESSURE; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 5; DIURETICS; ENALAPRIL; EPITHELIAL SODIUM CHANNELS; FEMALE; KIDNEY MEDULLA; LOSARTAN; NEPHRONS; NIFEDIPINE; PREGNANCY; RATS; RATS, SPRAGUE-DAWLEY; RENIN-ANGIOTENSIN SYSTEM; SODIUM; SODIUM NITRITE; SPIRONOLACTONE; VASODILATION; VASODILATOR AGENTS;

EID: 84887603041     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00003.2013     Document Type: Article

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