Radiosensitization of breast cancer cells by TRAIL-endostatin-targeting gene therapy

Neoplasma

Volumn 60, Issue 6, 2013, Pages 613-619

  Li, Y B ^a   Guo, C X ^a   Wang, Z C ^b   Dong, L H ^c   Guan, F ^c   Liu, Y ^b   Wang, H F ^b   Sun, Z W ^a   Gong, S L ^b  

^a CAPITAL MEDICAL UNIVERSITY   (China)

^b Center for Radiological Research   (China)

^c THE FIRST HOSPITAL OF JILIN UNIVERSITY   (China)

Author keywords

Egr 1; Endostatin; Gene radiotherapy; TRAIL

Indexed keywords

EARLY GROWTH RESPONSE FACTOR 1; ENDOSTATIN; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BREAST CANCER; CANCER GENE THERAPY; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE PROGRESSION; CELL VIABILITY; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; RADIATION DOSE; RADIOSENSITIZATION; TUMOR GROWTH; X IRRADIATION; BREAST TUMOR; CELL CYCLE; CELL PROLIFERATION; FEMALE; GENE THERAPY; GENETICS; PATHOLOGY; PLASMID; PROMOTER REGION; TUMOR CELL CULTURE; WESTERN BLOTTING; X RAY;

APOPTOSIS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL CYCLE; CELL PROLIFERATION; EARLY GROWTH RESPONSE PROTEIN 1; ENDOSTATINS; FEMALE; GENETIC THERAPY; HUMANS; PLASMIDS; PROMOTER REGIONS, GENETIC; RADIATION TOLERANCE; TNF-RELATED APOPTOSIS-INDUCING LIGAND; TUMOR CELLS, CULTURED; X-RAYS;

EID: 84887519429     PISSN: 00282685     EISSN: 13384317     Source Type: Journal    
DOI: 10.4149/neo_2013_079     Document Type: Article

References (32)

1. JEMAL A, SIEGEL R, WARD E, HAO Y, XU J, et al. Cancer statistics, 2009. CA Cancer J Clin 2009; 59: 225-49. http://dx.doi.org/10.3322/caac.20006
2. WEICHSELBAUM RR, HALLAHAN DE, SUKHATME VP, KUFE DW. Gene therapy targeted by ionizing radiation. Int J Radiat Oncol Biol Phys 1992; 24: 565-7. http://dx.doi.org/10.1016/0360-3016(92)91075-X
3. KALIBEROV SA, KALIBEROVA LN, BUCHSBAUM DJ. Combined ionizing radiation and sKDR gene delivery for treatment of prostate carcinomas. Gene Ther 2005; 12: 407-17. http://dx.doi.org/10.1038/sj.gt.3302432
4. KHODAREV NN, PARK JO, YU J, GUPTA N, NODZENSKI E, et al. Dose-dependent and independent temporal patterns of gene responses to ionizing radiation in normal and tumor cells and tumor xenografts. Proc Natl Acad Sci U S A 2001; 98: 12665-70. http://dx.doi.org/10.1073/pnas.211443698
5. MIN FL, ZHANG H, LI WJ. Current status of tumor radiogenic therapy. World J Gastroenterol 2005; 11: 3014-9.
6. YANG J, JIN G, LIU X, LIU S. Therapeutic effect of pEgr-IL18-B7.2 gene radiotherapy in B16 melanoma-bearing mice. Hum Gene Ther 2007; 18: 323-32. http://dx.doi.org/10.1089/hum.2006.133
7. JIN GH, JIN SZ, LIU Y, XU RM, YANG JZ, et al. Therapeutic effect of gene-therapy in combination with local X-irradiation in a mouse malignant melanoma model. Biochem Biophys Res Commun 2005; 330: 975-81. http://dx.doi.org/10.1016/j.bbrc.2005.03.070
8. WILEY SR, SCHOOLEY K, SMOLAK PJ, DIN WS, HUANG CP, et al. Identification and characterization of a new member of the TNF family that induces apoptosis. Immunity 1995; 3: 673-82. http://dx.doi.org/10.1016/1074-7613(95)90057-8
9. PITTI RM, MARSTERS SA, RUPPERT S, DONAHUE CJ, MOORE A, et al. Induction of apoptosis by Apo-2 ligand, a new member of the tumor necrosis factor cytokine family. J Biol Chem 1996; 271: 12687-90. http://dx.doi.org/10.1074/jbc.271.22.12687
10. ASHKENAZI A, HOLLAND P, ECKHARDT SG. Ligandbased targeting of apoptosis in cancer: the potential of recombinant human apoptosis ligand 2/Tumor necrosis factor-related apoptosis-inducing ligand (rhApo2L/TRAIL). J Clin Oncol 2008; 26: 3621-30. http://dx.doi.org/10.1200/JCO.2007.15.7198
11. DUIKER EW, MOM CH, DE JONG S, WILLEMSE PH, GIETEMA JA, et al. The clinical trail of TRAIL. Eur J Cancer 2006; 42: 2233-40. http://dx.doi.org/10.1016/j.ejca.2006.03.018
12. YOO J, PARK SS, LEE YJ. Pretreatment of docetaxel enhances TRAIL-mediated apoptosis in prostate cancer cells. J Cell Biochem 2008; 104: 1636-46. http://dx.doi.org/10.1002/jcb.21729
13. O'REILLY MS, BOEHM T, SHING Y, FUKAI N, VASIOS G, et al. Endostatin: an endogenous inhibitor of angiogenesis and tumor growth. Cell 1997; 88: 277-85. http://dx.doi.org/10.1016/S0092-8674(00)81848-6
14. KISKER O, BECKER CM, PROX D, FANNON M, D'AMATO R, et al. Continuous administration of endostatin by intraperitoneally implanted osmotic pump improves the efficacy and potency of therapy in a mouse xenograft tumor model. Cancer Res 2001; 61: 7669-74.
15. LEE J, HAMPL M, ALBERT P, FINE HA. Antitumor activity and prolonged expression from a TRAIL-expressing adenoviral vector. Neoplasia 2002; 4: 312-23. http://dx.doi.org/10.1038/sj.neo.7900245
16. WEICHSELBAUM RR, KUFE DW, ADVANI SJ, ROIZMAN B. Molecular targeting of gene therapy and radiotherapy. Acta Oncol 2001; 40: 735-8. http://dx.doi.org/10.1080/02841860152619151
17. LI YB, LIANG S, DONG LH, YANG W, GUO CX, et al. Construction and identification of recombinant adenoviral shuttle vector with radiation-inducible TRAIL gene (in Chinese). Journal of Jilin University (Medicine Edition) 2008; 34: 364-368.
18. LI YB, GUO CX, GONG PS, LIU Y, LIANG S, et al. Construction and identification of double-gene co-expression vector with radiation-inducible human TRAIL and endostatin (in Chinese). Journal of Jilin University (Medicine Edition) 2010; 36: 1007-11.
19. LI Z, DULLMANN J, SCHIEDLMEIER B, SCHMIDT M, VON KALLE C, et al. Murine leukemia induced by retroviral gene marking. Science 2002; 296: 497. http://dx.doi.org/10.1126/science.1068893
20. MARSHALL E. Clinical research. Gene therapy a suspect in leukemia-like disease. Science 2002; 298: 34-5. http://dx.doi.org/10.1126/science.298.5591.34
21. TSURUSHIMA H, YUAN X, DILLEHAY LE, LEONG KW. Radiation-inducible caspase-8 gene therapy for malignant brain tumors. Int J Radiat Oncol Biol Phys 2008; 71: 517-25. http://dx.doi.org/10.1016/j.ijrobp.2008.02.002
22. WEICHSELBAUM RR, HALLAHAN DE, BECKETT MA, MAUCERI HJ, LEE H, et al. Gene therapy targeted by radiation preferentially radiosensitizes tumor cells. Cancer Res 1994; 54: 4266-9.
23. YANG W, LI XY. Anti-tumor effect of pEgr-interferon-gammaendostatin gene-radiotherapy in mice bearing Lewis lung carcinoma and its mechanism. Chin Med J (Engl) 2005; 118: 296-301.
24. XIAN J, YANG H, LIN Y, LIU S. Combination nonviral murine interleukin 2 and interleukin 12 gene therapy and radiotherapy for head and neck squamous cell carcinoma. Arch Otolaryngol Head Neck Surg 2005; 131: 1079-85. http://dx.doi.org/10.1001/archotol.131.12.1079
25. MIZUGUCHI H, XU Z, ISHII-WATABE A, UCHIDA E, HAYAKAWA T. IRES-dependent second gene expression is significantly lower than cap-dependent first gene expression in a bicistronic vector. Mol Ther 2000; 1: 376-82. http://dx.doi.org/10.1006/mthe.2000.0050
26. Suliman A, Lam A, Datta R, SRIVASTAVA RK. Intracellular mechanisms of TRAIL: apoptosis through mitochondrialdependent and-independent pathways. Oncogene 2001; 20: 2122-33. http://dx.doi.org/10.1038/sj.onc.1204282
27. GRIFFITH TS, ANDERSON RD, DAVIDSON BL, WILLIAMS RD, RATLIFF TL. Adenoviral-mediated transfer of the TNFrelated apoptosis-inducing ligand/Apo-2 ligand gene induces tumor cell apoptosis. J Immunol 2000; 165: 2886-94.
28. FOLKMAN J. Antiangiogenesis in cancer therapy--endostatin and its mechanisms of action. Exp Cell Res 2006; 312: 594-607. http://dx.doi.org/10.1016/j.yexcr.2005.11.015
29. NYBERG P, XIE L, KALLURI R. Endogenous inhibitors of angiogenesis. Cancer Res 2005; 65: 3967-79. http://dx.doi.org/10.1158/0008-5472.CAN-04-2427
30. JIANG J, CHEN W, ZHUANG R, SONG T, LI P. The effect of endostatin mediated by human mesenchymal stem cells on ovarian cancer cells in vitro. J Cancer Res Clin Oncol 2010; 136: 873-81. http://dx.doi.org/10.1007/s00432-009-0728-8
31. CHINNAIYAN AM, PRASAD U, SHANKAR S, HAMSTRA DA, SHANAIAH M, et al. Combined effect of tumor necrosis factor-related apoptosis-inducing ligand and ionizing radiation in breast cancer therapy. Proc Natl Acad Sci U S A 2000; 97: 1754-9. http://dx.doi.org/10.1073/pnas.030545097
32. DI PIETRO R, SECCHIERO P, RANA R, GIBELLINI D, VISANI G, et al. Ionizing radiation sensitizes erythroleukemic cells but not normal erythroblasts to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)--mediated cytotoxicity by selective up-regulation of TRAIL-R1. Blood 2001; 97: 2596-603. http://dx.doi.org/10.1182/blood.V97.9.2596