-
1
-
-
0035254858
-
Clinical pharmacogenomics: Aplications in pharmaceutical R&D
-
Norton RM. Clinical pharmacogenomics: aplications in pharmaceutical R&D. Drugs Discov Today. 2001;6(4):180-185.
-
(2001)
Drugs Discov Today
, vol.6
, Issue.4
, pp. 180-185
-
-
Norton, R.M.1
-
2
-
-
79953296501
-
Pharmacogenetic implications of the eNOS polymorphisms for cardiovascular action drugs
-
Silva PS, Lacchini R, Gomes Vde A, Tanus-Santos JE. Pharmacogenetic implications of the eNOS polymorphisms for cardiovascular action drugs. Arq Bras Cardiol. 2011;96(2):e27-34.
-
(2011)
Arq Bras Cardiol
, vol.96
, Issue.2
-
-
Silva, P.S.1
Lacchini, R.2
Gomes Vde, A.3
Tanus-Santos, J.E.4
-
3
-
-
65549115939
-
Genome-wide association studies: Powerful tools for improving drug safety and efficacy
-
Gurwitz D, McLeod HL. Genome-wide association studies: powerful tools for improving drug safety and efficacy. Pharmacogenomics. 2009;10(2):157-159.
-
(2009)
Pharmacogenomics
, vol.10
, Issue.2
, pp. 157-159
-
-
Gurwitz, D.1
McLeod, H.L.2
-
4
-
-
77957946877
-
The role of molecular biology in the diagnosis and treatment of cardiovascular diseases
-
Mariotti S, Capparuccia C, Ripa C, Olivieri F, Lisa R, Procópio A, et al. The role of molecular biology in the diagnosis and treatment of cardiovascular diseases. G Ital Cardiol (Rome). 2010;11(10):730-745.
-
(2010)
G Ital Cardiol (Rome)
, vol.11
, Issue.10
, pp. 730-745
-
-
Mariotti, S.1
Capparuccia, C.2
Ripa, C.3
Olivieri, F.4
Lisa, R.5
Procópio, A.6
-
5
-
-
0023192279
-
Interindividual pharmacokinetic and pharmacodynamic variability of different beta blockers
-
Dayer P, Mérier G, Perrenoud JJ, Marmy A, Leemann T. Interindividual pharmacokinetic and pharmacodynamic variability of different beta blockers. J Cardiovasc Pharmacol. 1986;8 Suppl 6:S20-24.
-
(1986)
J Cardiovasc Pharmacol
, vol.8
, Issue.SUPPL. 6
, pp. 20-24
-
-
Dayer, P.1
Mérier, G.2
Perrenoud, J.J.3
Marmy, A.4
Leemann, T.5
-
6
-
-
79955695436
-
Individual renal hemodynamic response to chronic angiotensin II receptor blockade and the influence on the renin-angiotensin system gene polymorphisms
-
Dragovic T, Ajdinovic B, Ilic V, Magić Z, Andelković Z, Kocev N. Individual renal hemodynamic response to chronic angiotensin II receptor blockade and the influence on the renin-angiotensin system gene polymorphisms. Med Pregl. 2010;63(9-10):630-637.
-
(2010)
Med Pregl
, vol.63
, Issue.9-10
, pp. 630-637
-
-
Dragovic, T.1
Ajdinovic, B.2
Ilic, V.3
Magić, Z.4
Andelković, Z.5
Kocev, N.6
-
7
-
-
77954696448
-
From mechanics to genetics in cardiology
-
Wilkinson E. From mechanics to genetics in cardiology. Eur Heart J. 2009;30(19):2291-2293.
-
(2009)
Eur Heart J
, vol.30
, Issue.19
, pp. 2291-2293
-
-
Wilkinson, E.1
-
8
-
-
0036812536
-
The role of NOS in heart failure: Lessons from murine genetic models
-
Mungrue IN, Husain M, Stewart DJ. The role of NOS in heart failure: lessons from murine genetic models. Heart Fail Rev. 2002;7(4):407-422.
-
(2002)
Heart Fail Rev
, vol.7
, Issue.4
, pp. 407-422
-
-
Mungrue, I.N.1
Husain, M.2
Stewart, D.J.3
-
9
-
-
0033940633
-
Expression of nitric oxide synthases in the pathophysiology of cardiovascular diseases
-
Viaro F, Nobre F, Evora PR. Expression of nitric oxide synthases in the pathophysiology of cardiovascular diseases. Arq Bras Cardiol. 2000;74(4):380-393.
-
(2000)
Arq Bras Cardiol
, vol.74
, Issue.4
, pp. 380-393
-
-
Viaro, F.1
Nobre, F.2
Evora, P.R.3
-
10
-
-
0033609027
-
Decreased activity of the L-arginine-nitric oxide metabolic pathway in patients with congestive heart failure
-
Katz SD, Khan T, Zeballos GA, Mathew L, Potharlanka P, Knecht M, et al. Decreased activity of the L-arginine-nitric oxide metabolic pathway in patients with congestive heart failure. Circulation. 1999;99(16):2113-2117.
-
(1999)
Circulation
, vol.99
, Issue.16
, pp. 2113-2117
-
-
Katz, S.D.1
Khan, T.2
Zeballos, G.A.3
Mathew, L.4
Potharlanka, P.5
Knecht, M.6
-
11
-
-
79951602338
-
Nitric oxide and the cardiovascular system: Cell activation, vascular reactivity and genetic variant
-
Dias RG, Negrão CE, Krieger MH. Nitric oxide and the cardiovascular system: cell activation, vascular reactivity and genetic variant. Arq Bras Cardiol. 2011;96(1):68-75.
-
(2011)
Arq Bras Cardiol
, vol.96
, Issue.1
, pp. 68-75
-
-
Dias, R.G.1
Negrão, C.E.2
Krieger, M.H.3
-
12
-
-
61849130045
-
Genetic variations in nitric oxide Synthase 1 adaptor protein are associated with sudden death in US white community-based populations
-
Kao WH, Arking DE, Post W, Rea TD, Sotoodehnia N, Prineas RJ, et al. Genetic variations in nitric oxide Synthase 1 adaptor protein are associated with sudden death in US white community-based populations. Circulation. 2009;119(7):940-951.
-
(2009)
Circulation
, vol.119
, Issue.7
, pp. 940-951
-
-
Kao, W.H.1
Arking, D.E.2
Post, W.3
Rea, T.D.4
Sotoodehnia, N.5
Prineas, R.J.6
-
13
-
-
0027183208
-
Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene
-
Marsden PA, Heng HH, Scherer S W, Stewart RJ, Hall A V, Shi XM, et al. Structure and chromosomal localization of the human constitutive endothelial nitric oxide synthase gene. J Biol Chem. 1993;268(23):17478-17488.
-
(1993)
J Biol Chem
, vol.268
, Issue.23
, pp. 17478-17488
-
-
Marsden, P.A.1
Heng, H.H.2
Scherer, S.W.3
Stewart, R.J.4
Hall, A.V.5
Shi, X.M.6
-
14
-
-
77956632785
-
Association of eNOS E298D polymorphism and the risk of myocardial infarction in the Greek population
-
Dafni C, Drakoulis N, Landt O, Panidis D, Reczko M, Cokkinos D V. Association of eNOS E298D polymorphism and the risk of myocardial infarction in the Greek population. BMC Med Genet. 2010;11:133.
-
(2010)
BMC Med Genet
, vol.11
, pp. 133
-
-
Dafni, C.1
Drakoulis, N.2
Landt, O.3
Panidis, D.4
Reczko, M.5
Cokkinos, D.V.6
-
15
-
-
14844293932
-
A polymorphism of endo thelial nitric oxide synthase promoter is associated with an increase in autonomic imbalance in patients with congestive heart failure
-
Binkley P F, Nunziatta E, Liu-Stratton Y, Cooke G. A polymorphism of endo thelial nitric oxide synthase promoter is associated with an increase in autonomic imbalance in patients with congestive heart failure. Am Heart J. 2005;149(2):342-348.
-
(2005)
Am Heart J
, vol.149
, Issue.2
, pp. 342-348
-
-
Binkley, P.F.1
Nunziatta, E.2
Liu-Stratton, Y.3
Cooke, G.4
-
16
-
-
0002058413
-
A common variant in exon 7 of endothelial constitutive nitric oxide synthase gene: Identification by single strand conformation polymorphism analysis
-
Hingorami AD, Jia H, Stevens P, Monteith P, Brown M, A common variant in exon 7 of endothelial constitutive nitric oxide synthase gene: identification by single strand conformation polymorphism analysis. Clin Sci. 1995;88(suppl):21.
-
(1995)
Clin Sci
, vol.88
, Issue.SUPPL.
, pp. 21
-
-
Hingorami, A.D.1
Jia, H.2
Stevens, P.3
Monteith, P.4
Brown, M.5
-
17
-
-
0037394422
-
Effect of the Asp 298 variant of endothelial nitric oxide synthase on survival for patients with congestive heart failure
-
MacNamara DM, Holubkov R, Postava L, Ramani R, Janosko K, Mathier M, et al. Effect of the Asp 298 variant of endothelial nitric oxide synthase on survival for patients with congestive heart failure, Circulation. 2003;107(12):1598-1602.
-
(2003)
Circulation
, vol.107
, Issue.12
, pp. 1598-1602
-
-
Macnamara, D.M.1
Holubkov, R.2
Postava, L.3
Ramani, R.4
Janosko, K.5
Mathier, M.6
-
18
-
-
26444578461
-
The African-American Heart Failure Trial: A clinical trial update
-
Taylor AL, The African-American Heart Failure Trial: a clinical trial update. Am J Cardiol. 2005;96(7B):44-48.
-
(2005)
Am J Cardiol
, vol.96
, Issue.7
, pp. 44-48
-
-
Taylor, A.L.1
-
19
-
-
62649122885
-
Endothelial nitric oxide synthase (NOS3) polymorphisms in African Americans with heart failure: Results from the A-HeFT trial
-
McNamara DM, Tam SW, Sabolinski ML, Tobelmann P, Janosko K, Venkitachalam L, et al. Endothelial nitric oxide synthase (NOS3) polymorphisms in African Americans with heart failure: results from the A-HeFT trial. J Card Fail. 2009;15(3):191-198.
-
(2009)
J Card Fail
, vol.15
, Issue.3
, pp. 191-198
-
-
McNamara, D.M.1
Tam, S.W.2
Sabolinski, M.L.3
Tobelmann, P.4
Janosko, K.5
Venkitachalam, L.6
-
20
-
-
76949104757
-
Endohelial nitric oxide synthase Glu298Asp gene polymorphism in a multi-ethnical population with heart failure and controls
-
Velloso MW, Pereira S P, Gouveia L, Chermont S, Tardin OM, Gonçalves R, et al. Endohelial nitric oxide synthase Glu298Asp gene polymorphism in a multi-ethnical population with heart failure and controls. Nitric Oxide. 2010;22(3):220-225.
-
(2010)
Nitric Oxide
, vol.22
, Issue.3
, pp. 220-225
-
-
Velloso, M.W.1
Pereira, S.P.2
Gouveia, L.3
Chermont, S.4
Tardin, O.M.5
Gonçalves, R.6
-
21
-
-
3543021425
-
Sociedade Brasileira de Cardiologia. II Diretrizes da Sociedade Brasileira de Cardiologia para o diagnóstico e tratamento da insuficiência cardíaca
-
Barretto AC, Drumond Neto C, Mady C, Albuquerque DC, Brindeiro Filho D, Braile DM, et al. Sociedade Brasileira de Cardiologia. II Diretrizes da Sociedade Brasileira de Cardiologia para o diagnóstico e tratamento da insuficiência cardíaca. Arq Bras Cardiol. 2002;79(suppl.4):1-30.
-
(2002)
Arq Bras Cardiol
, vol.79
, Issue.SUPPL. 4
, pp. 1-30
-
-
Barretto, A.C.1
Drumond Neto, C.2
Mady, C.3
Albuquerque, D.C.4
Brindeiro Filho, D.5
Braile, D.M.6
-
22
-
-
77953648909
-
Frequency of eNOS polymorphisms in the Colombian general population
-
Serrano NC, Díaz LA, Casas J P, Hingorani AD, Moreno de Lucca D, Páez MC. Frequency of eNOS polymorphisms in the Colombian general population. BMC Genet. 2010;11:54.
-
(2010)
BMC Genet
, vol.11
, pp. 54
-
-
Serrano, N.C.1
Díaz, L.A.2
Casas, J.P.3
Hingorani, A.D.4
De Moreno, L.D.5
Páez, M.C.6
-
23
-
-
12144286853
-
Epidemiologia da Insuficiência Cardíaca Descompensada em Niterói - Projeto EPICA - Niterói
-
121-124
-
Tavares LR, Victer H, Linhares JM, de Barros CM, Oliveira MV, Pacheco LC, et al. Epidemiologia da Insuficiência Cardíaca Descompensada em Niterói - Projeto EPICA - Niterói. Arq Bras Cardiol. 2004;82(2):125-128, 121-124.
-
(2004)
Arq Bras Cardiol
, vol.82
, Issue.2
, pp. 125-128
-
-
Tavares, L.R.1
Victer, H.2
Linhares, J.M.3
de Barros, C.M.4
Oliveira, M.V.5
Pacheco, L.C.6
-
24
-
-
77951614170
-
Mortality due to heart failure as a basic or contributory cause of death in three Brazilian states between 1999 and 2004
-
Gaui EN, Klein CH, Oliveira GM. Mortality due to heart failure as a basic or contributory cause of death in three Brazilian states between 1999 and 2004. Rev SOCERJ. 2008;21(3):129-137.
-
(2008)
Rev SOCERJ
, vol.21
, Issue.3
, pp. 129-137
-
-
Gaui, E.N.1
Klein, C.H.2
Oliveira, G.M.3
-
25
-
-
79958172224
-
Chronic non-communicable diseases in Brazil: Burden and current challenges
-
Schmidt MI, Duncan BB, Azevedo e Silva G, Menezes AM, Monteiro CA, Barreto SM, et al. Chronic non-communicable diseases in Brazil: burden and current challenges. Lancet. 2011;377(9781):1949-1961.
-
(2011)
Lancet
, vol.377
, Issue.9781
, pp. 1949-1961
-
-
Schmidt, M.I.1
Duncan, B.B.2
Azevedo Silva, G.3
Menezes, A.M.4
Monteiro, C.A.5
Barreto, S.M.6
-
26
-
-
0031748762
-
Association of missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myocardial infarction
-
Shimasaki Y, Yasue H, Yoshimura M, Nakayama M, Kugiyama K, Ogawa H, et al. Association of missense Glu298Asp variant of the endothelial nitric oxide synthase gene with myocardial infarction. J Am Coll Cardiol. 1998;31(7):1506-1510.
-
(1998)
J Am Coll Cardiol
, vol.31
, Issue.7
, pp. 1506-1510
-
-
Shimasaki, Y.1
Yasue, H.2
Yoshimura, M.3
Nakayama, M.4
Kugiyama, K.5
Ogawa, H.6
-
27
-
-
0345192295
-
A common variant of the endothelial nitric oxide synthase (Glu 298→Asp) is a major risk factor for coronary artery disease in the UK
-
Hingorani AD, Liang C F, Fatibene J, Lyon A, Monteith S, Parsons A, et al. A common variant of the endothelial nitric oxide synthase (Glu 298→Asp) is a major risk factor for coronary artery disease in the UK. Circulation. 1999;100(14):1515-1520.
-
(1999)
Circulation
, vol.100
, Issue.14
, pp. 1515-1520
-
-
Hingorani, A.D.1
Liang, C.F.2
Fatibene, J.3
Lyon, A.4
Monteith, S.5
Parsons, A.6
-
28
-
-
77955868822
-
Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: A prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium
-
Smith NL, Felix J F, Morrison AC, Demissie S, Glazer NL, Loehr LR, et al. Association of genome-wide variation with the risk of incident heart failure in adults of European and African ancestry: a prospective meta-analysis from the cohorts for heart and aging research in genomic epidemiology (CHARGE) consortium. Circ Cardiovasc Genet. 2010;3(3):256-266.
-
(2010)
Circ Cardiovasc Genet
, vol.3
, Issue.3
, pp. 256-266
-
-
Smith, N.L.1
Felix, J.F.2
Morrison, A.C.3
Demissie, S.4
Glazer, N.L.5
Loehr, L.R.6
-
29
-
-
80052186988
-
A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy
-
Villard E, Perret C, Gary F, Proust C, Dilanian G, Hengstenberget C, et al. A genome-wide association study identifies two loci associated with heart failure due to dilated cardiomyopathy. Eur Heart J. 2011;32(9):1065-1076.
-
(2011)
Eur Heart J
, vol.32
, Issue.9
, pp. 1065-1076
-
-
Villard, E.1
Perret, C.2
Gary, F.3
Proust, C.4
Dilanian, G.5
Hengstenberget, C.6
-
30
-
-
79959503826
-
The International HapMap Project
-
International HapMap Consortium
-
International HapMap Consortium. The International HapMap Project. Nature. 2003;426(6968):789-796.
-
(2003)
Nature
, vol.426
, Issue.6968
, pp. 789-796
-
-
|